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Taking tissue regeneration beyond the state-of-the-art
Date:7/6/2012

patients with broken bones that are not healing.

In general, the body's wound repair process works in much the same way regardless of what the condition is or which organ is affected. For instance; the sequence of events that follows a heart attack is similar to the process that takes place following spinal-cord injury. The aim of regenerative medicine is to create a 'seed bed' from which tissue can grow. This technique will lead to more effective and affordable treatments for diseases such as cancer and osteoporosis and for patients who have suffered a heart attack or experienced major trauma.

Nanotechnology for drug delivery

Nottingham and UNMC are developing a new class of injectable material that stimulates stem cells to form new blood vessels, heart and bone tissue.

For more information go to: http://tiny.cc/BioDesign

Professor Shakesheff said: "Biodesign brings together some of the best research groups in Europe to develop new therapies that regenerate human tissue. The opportunity to extend the work through links with our Malaysia Campus opens new opportunities to make an impact on the development of regenerative medicine in the Far East."

UNMC is building on its expertise in nanotechnology for drug delivery. Dr Andrew Morris, an expert in transdermal drug delivery at UNMC, said: "Our understanding of genomics and tissue regeneration means that medicines of the future will be much smarter. We are moving away from simple drugs being given to a patient in a tablet and hoping that they will have the desired effect. Here in Malaysia we are looking at synthesising microparticles which can potentially be injected directly into a patient at the site of injury to promote tissue re-growth. These microparticles would act as a scaffold to encourage regrowth in bone tissue, skeletal muscle and potentially even cardiac muscle."

Dr Nashiru Billa, a
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Contact: Lindsay Brooke
lindsay.brooke@nottingham.ac.uk
44-115-951-5751
University of Nottingham
Source:Eurekalert

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