Navigation Links
Taking a break from osteoporosis drugs can protect bones
Date:11/18/2010

MAYWOOD, Ill. -- Taking time off from certain osteoporosis drugs may be beneficial to bone health, according to a study conducted at Loyola University Health System. Researchers found that bone density remained stable for three years in patients who took a drug holiday from bisphosphonates, a popular class of osteoporosis drugs that can cause fractures in the thigh bones and tissue decay in the jaw bone.

"These drugs are potentially harmful when taken for long durations, yet little has been known until now about the length of time osteoporosis patients should go without treatment for this debilitating condition," said Pauline Camacho, MD, study investigator and director of the Loyola University Osteoporosis and Metabolic Bone Disease Center. "Our study demonstrated that bones can remain stable for a number of years after these drugs are discontinued."

Doctors recommend that patients take drug holidays from bisphosphonates after four to five years. These drugs continue to stabilize bones and reduce the risk for bone loss after treatment ceases.

The study's goal was to identify the optimal drug holiday length after prolonged use of bisphosphonates based on changes in bone mineral density and bone loss. The study evaluated 139 patients (123 females, 16 males) with osteoporosis and osteopenia, the precursor to the disease. Patients took a bisphosphonate an average of 6.8 years before beginning a drug holiday from 2005 to 2010. Over three years, five fractures occurred, but bone mineral density did not change significantly. However, bone loss did start to increase at six months. The type of bisphosphonate and the duration of treatment did not affect bone mineral density.

"While further research is needed to adequately assess the optimal duration of the drug holiday, we do know that patients can relatively safely discontinue their treatment for at least three years," Dr. Camacho said. "However, patients who fracture during their drug holiday should notify their physician right away so osteoporosis therapy can be resumed. Patients also should continue to see their physician to regularly monitor their bone health."


'/>"/>

Contact: Nora Plunkett
nplunkett@lumc.edu
708-216-6268
Loyola University Health System
Source:Eurekalert

Related medicine news :

1. Celebrate National Childrens Dental Health Month by Taking Care of Tiny Teeth
2. People with prediabetes not taking adequate precautions to avoid diabetes
3. Binge drinking doesnt affect next-day student test-taking
4. Taking Care of Your 'Girls': A Fun and Open Forum for Young Women Hosted by Abington Memorial Hospital
5. Triple Heart Valve Replacement Saves Local Women's Life at Portneuf Medical Center: Woman Gets a Second Chance at Life After Taking Fen-Phen
6. Taking Flu Drugs While Pregnant Appears to Be Safe: Study
7. Harmony Information Systems to Host Free Webcast: Learn How Vermont and Pennsylvania Are Taking Control of Medicaid Waivers Management
8. A Womans Touch Encourages Financial Risk-Taking
9. Taking the final step from the bench to the hospital or clinic bedside
10. Robin Leedy & Associates Hires Digital Content Producer, Taking Social Media for Drugstore Brands Digital Capability to the Next Level
11. Genetic differences may influence joint pain among women taking lifesaving breast cancer drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2016)... ... ... In a part of the city where’s it’s easy to spot the neon lights of ... hoping to attract diners with a taste for real food. , On May 13, ... Cornerstone Grill, an urban casual restaurant focusing on dishes made by hand with wholesome, organic ...
(Date:5/27/2016)... ... May 27, 2016 , ... W.S. Badger Co. Inc ., ... it has been recognized as one of the best small businesses for new dads ... one of nine small businesses providing progressive benefits to new parents on the organization’s ...
(Date:5/27/2016)... ... 27, 2016 , ... An educational campaign aimed at everyone ... courtesy of awareness-driven celebrities and thought leaders. It also provides insight to the ... leaders such as Bioness. , As patients feel increasingly concerned about the ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed at nurses and ... stories, which come courtesy of leaders in the nursing and health care industry. It ... advocates and associations—namely Abilene Christian University. , As the nursing industry is coming ...
(Date:5/26/2016)... ... May 26, 2016 , ... There are many ways ... and Sausage Council (NHDSC) suggests that Americans prefer their dogs straight off the grill. ... say grilling is their favorite way to cook a hot dog, far outpacing other ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... NASHVILLE, Tenn. , May 26, 2016 ... provider of software and analytics, network solutions ... healthcare, today announced it entered into a ... leading provider of outpatient software solutions and ... surgery centers, specialty hospitals and rehabilitation clinics ...
(Date:5/25/2016)... and GERMANTOWN, Maryland , May 25, 2016 ... ; Frankfurt Prime Standard: QIA) today announced that the company ... Diagnostics GmbH to develop and commercialize predictive assays in oncology. ... as a marker to predict effectiveness of anthracycline treatment in ... "We are pleased to partner with Therawis, which developed the ...
(Date:5/25/2016)... , May 25, 2016  Granger Diagnostics today ... test for wounds and infections. This test ensures ... and select viruses. The test requires only a ... David G. Bostwick , MD, ... to facilitate wound healing: "We are excited to ...
Breaking Medicine Technology: