Navigation Links
Taking a break from osteoporosis drugs can protect bones
Date:11/18/2010

MAYWOOD, Ill. -- Taking time off from certain osteoporosis drugs may be beneficial to bone health, according to a study conducted at Loyola University Health System. Researchers found that bone density remained stable for three years in patients who took a drug holiday from bisphosphonates, a popular class of osteoporosis drugs that can cause fractures in the thigh bones and tissue decay in the jaw bone.

"These drugs are potentially harmful when taken for long durations, yet little has been known until now about the length of time osteoporosis patients should go without treatment for this debilitating condition," said Pauline Camacho, MD, study investigator and director of the Loyola University Osteoporosis and Metabolic Bone Disease Center. "Our study demonstrated that bones can remain stable for a number of years after these drugs are discontinued."

Doctors recommend that patients take drug holidays from bisphosphonates after four to five years. These drugs continue to stabilize bones and reduce the risk for bone loss after treatment ceases.

The study's goal was to identify the optimal drug holiday length after prolonged use of bisphosphonates based on changes in bone mineral density and bone loss. The study evaluated 139 patients (123 females, 16 males) with osteoporosis and osteopenia, the precursor to the disease. Patients took a bisphosphonate an average of 6.8 years before beginning a drug holiday from 2005 to 2010. Over three years, five fractures occurred, but bone mineral density did not change significantly. However, bone loss did start to increase at six months. The type of bisphosphonate and the duration of treatment did not affect bone mineral density.

"While further research is needed to adequately assess the optimal duration of the drug holiday, we do know that patients can relatively safely discontinue their treatment for at least three years," Dr. Camacho said. "However, patients who fracture during their drug holiday should notify their physician right away so osteoporosis therapy can be resumed. Patients also should continue to see their physician to regularly monitor their bone health."


'/>"/>

Contact: Nora Plunkett
nplunkett@lumc.edu
708-216-6268
Loyola University Health System
Source:Eurekalert

Related medicine news :

1. Celebrate National Childrens Dental Health Month by Taking Care of Tiny Teeth
2. People with prediabetes not taking adequate precautions to avoid diabetes
3. Binge drinking doesnt affect next-day student test-taking
4. Taking Care of Your 'Girls': A Fun and Open Forum for Young Women Hosted by Abington Memorial Hospital
5. Triple Heart Valve Replacement Saves Local Women's Life at Portneuf Medical Center: Woman Gets a Second Chance at Life After Taking Fen-Phen
6. Taking Flu Drugs While Pregnant Appears to Be Safe: Study
7. Harmony Information Systems to Host Free Webcast: Learn How Vermont and Pennsylvania Are Taking Control of Medicaid Waivers Management
8. A Womans Touch Encourages Financial Risk-Taking
9. Taking the final step from the bench to the hospital or clinic bedside
10. Robin Leedy & Associates Hires Digital Content Producer, Taking Social Media for Drugstore Brands Digital Capability to the Next Level
11. Genetic differences may influence joint pain among women taking lifesaving breast cancer drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2017)... ... June 20, 2017 , ... Caduceus International Publishing (CIP), a ... a new online course entitled Personal & Community Health for the ... for achieving optimal well-being and teaches students how to apply them in their ...
(Date:6/20/2017)... ... June 20, 2017 , ... Kenneth Mayer, MD, has been appointed ... , Dr. Mayer, who joined the JIAS Editorial Board in 2016, has co-authored more ... Director of Fenway Health and Co-Chair of The Fenway Institute, a member ...
(Date:6/20/2017)... (PRWEB) , ... June 20, 2017 , ... AMC ... continued expansion and success in the clinical trials market. Similar to its approach in ... record in the clinical trials marketplace by proving the value of eVisits to support ...
(Date:6/20/2017)... Ohio (PRWEB) , ... June 20, 2017 , ... ... gum disease in Cincinnati, OH for leading-edge care, whether or not ... in laser dentistry. Using the BIOLASE WaterLase® iPlus™ laser, she targets bacteria and ...
(Date:6/20/2017)... PA (PRWEB) , ... June 20, 2017 , ... ... at Allegheny Health Network’s (AHN) Jefferson Hospital is providing physicians with advanced capabilities ... scanner provides higher-resolution images than traditional MRIs, enabling doctors to get a more ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... 6, 2017  Diplomat Specialty Infusion Group, a brand of Diplomat ... its Iowa location. The ... now features an ISO 7 cleanroom—the standard needed to compound intravenous ... low level of pollutants. "Our ... and better serve our Iowa patients," said ...
(Date:6/1/2017)... Nutriceutical Holdings (NH), parent company of Physician ... KD Pharma Group have decided to join forces through ... Group. KD Pharma Group will become the largest shareholder ... entire company. "We believe we have found ... growing the NH companies by providing us with supply ...
(Date:5/26/2017)... International plc (NASDAQ: ENDP ) announced today that ... Company in a fireside chat at Goldman Sachs, 38 th ... at 10:40 a.m. PT / 1:40 p.m. ET. The conference ... Palos Verdes, CA. A live webcast ... the Company,s website at http://www.endo.com/investors/overview . Participants should allow ...
Breaking Medicine Technology: