Navigation Links
Taking Statins Faithfully Lengthens Life
Date:2/9/2009

But experts note finding colored by fact that these folks take better care of themselves generally

MONDAY, Feb. 9 (HealthDay News) -- A massive Israeli study finds that people with high cholesterol levels who faithfully take statins are less likely to die over four to five years than those who neglect the therapy.

But that finding is not necessarily a tribute to the effectiveness of the cholesterol-lowering therapy, American experts said. Previous studies have shown that people who follow doctors orders about taking drugs are more likely to follow other rules of good health, they said.

The Israeli study of almost 230,000 middle-aged people enrolled in a health maintenance organization found a 45 percent lower death rate among those who took the drugs at least 90 percent of the time, compared to those taking the statins less than 10 percent of the time, according to a report in the Feb. 9 issue of the Archives of Internal Medicine by researchers at Maccabi Healthcare Services in Tel Aviv.

The risk reduction was true for both people who were prescribed a statin for secondary prevention, because they already had heart disease, and for primary prevention, to reduce the chance of having a first coronary event.

"The observed benefits from statins were greater than expected from randomized clinical trials, emphasizing the importance of promoting statin therapy and increasing its continuation over time for both primary and secondary prevention," the researchers wrote.

But it's not necessarily the statins that were responsible for all of the benefit, said Dr. Mark A. Hlatky, a professor of health research policy and medicine at Stanford University. He cited the Coronary Drug Project, done more than three decades ago, which showed an apparent benefit from faithfully taking a placebo.

"People who took placebo did much better than people who didn't take placebo," Hlatky said. They also did just about as well as people who took active drugs in the study.

For example, the five-year death rate for study participants who took the lipid-lowering drug clofibrate at least 80 percent of the time was 15 percent, compared to 24.6 percent of those who didn't follow orders.

But the numbers were virtually identical for those taking what they didn't know was a placebo -- a 15.1 percent mortality rate for those following the rules about taking the pill regularly, 28.3 percent for those not taking the pills as recommended, Hlatky said.

"It is definitely a very important observation that people who take their drugs always do better than people who don't, even if the drug is not terribly effective, because they tend to take better care of themselves better in a lot of ways," Hlatky said.

"While guidelines support the use of lipid-lowering medication in people with diabetes and other risk factors for coronary heart disease, they fall short in stipulating which class of lipid-lowering medication to use," said Dr. Erica Spatz, a fellow in the Robert Wood Johnson Clinical Scholars Program at Yale University.

More information

Statins and other cholesterol-lowering drugs are described by the American Heart Association.



SOURCES: Mark A. Hlatky, M.D., professor, health research policy and medicine, Stanford University, Stanford, Calif.; Erica Spatz, M.D., fellow, Robert Wood Johnson Clinical Scholars Program, Yale University, New Haven, Conn.; Feb. 9, 2009, Archives of Internal Medicine


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Depression Taking Toll on Returning U.S. Vets
2. 13 percent of women stop taking breast cancer drug because of side effects, U-M study finds
3. Study finds drug spending caps cause some seniors to quit taking key medicines
4. The Nutrition-Conscious Are Taking a Bite Out of Fast Food
5. New Resource for Taking Care of Aging Parents Available in Beta
6. Study finds drug spending caps cause some seniors to quit taking key medicines
7. Blue Cross And Blue Shield Association Survey Shows Consumer Driven Health Plan Enrollees Are Taking More Control of Their Healthcare
8. Taking the stress out of choosing the right stress test
9. Better Prostate Cancer Survival for Men Taking Statins
10. Multi-talented Entertainer Chris Brown Goes Back to School, Taking on a Starring Role in the St. Jude Math-A-Thon (R) Video
11. Mayo Clinic study finds that after heart attack most patients stop taking life-saving drugs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Taking Statins Faithfully Lengthens Life
(Date:7/26/2017)... PITTSBURGH, PA (PRWEB) , ... July 26, 2017 , ... ... braces,” said Dr. Ahmed Mauassra, from San Jose, Calif., “so we invented the MAGNETIC/ ... remove the bracket portion of orthodontic braces. In doing so, it offers an effective ...
(Date:7/26/2017)... ... July 26, 2017 , ... Team Type 1 Foundation, a nonprofit organization ... affected by diabetes, is excited to announce the 106 college athletes with type 1 ... Established in 2005, the Team Type 1 Foundation has bestowed a total of 271 ...
(Date:7/26/2017)... ... July 26, 2017 , ... Isodiol International ... cannabis innovator, specializing in the development of pharmaceutical and consumer products, announces the ... to June 30, 2017. Iso International LLC recorded unaudited fiscal Q1 profits of ...
(Date:7/26/2017)... ... , ... The number of adults 65 years or older is expected to ... control in the population are not well described. In a study published in The ... of the American Academy of Allergy, Asthma & Immunology (AAAAI), researchers identified factors associated ...
(Date:7/25/2017)... ... July 25, 2017 , ... Creative Pharmacist ... to provide the Pharmacist eCare Plan to Computer-Rx pharmacies through the ... the ability to develop the Pharmacist eCare Plan, a shared document detailing a ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... 13, 2017  Centurion Medical Products, a leader in medical product ... fecal impaction removal device for hospice patient care. ... Centurion Medical Products ... Patient pain management and emotional comfort are part ... alleviate patient pain while preventing unneeded emergency department admission due to ...
(Date:7/12/2017)... July 12, 2017  Eli Lilly and Company (NYSE: ... generic companies to resolve pending patent litigation in the U.S. ... regarding the Cialis ® (tadalafil) unit dose ... 26, 2020. As part of the agreement, Cialis exclusivity is ... 2018. "The unit dose patent for Cialis is ...
(Date:7/11/2017)... , July 11, 2017  Sysmex America, Inc., ... diagnostic testing equipment as well as middleware information ... way to make quality assurance easier and more ... is well known for the innovation that it ... Monitor elevates quality assurance processes to a new ...
Breaking Medicine Technology: