Navigation Links
Taiho Pharmaceutical unveils data on 8 novel anticancer compounds
Date:11/6/2012

colorectal cancer. Taiho took the encouraging results from this Phase II study and completed the required western Phase I studies to initiate a global Phase III program within a 15 month period.

Exploring New Treatment Options Alone and in Combination

Taiho has established a seamlessly connected research network, consisting of Tsukuba Research Center, Tokushima Research Center, the Taiho Clinical Development Center, and Taiho Pharma USA. The integrated network supports the discovery and development of numerous treatments. The Company's research achieves the highest standards of drug discovery by letting science guide its development path, and then applying modern technology and innovation to achieve that end. Investigational drugs stemming from this research are being examined as potential stand-alone products, or ones that can be used in combination with existing therapies to potentially enhance the safety and efficacy profile of current cancer options.

Highlights of the preclinical results of Taiho's investigational drugs being presented at the EORTC-NCI-AACR Symposium include:

  • TAS-114, a first-in-class dUTPase (deoxyuridine 5'-triphosphate nucleotidehydrolase) and DPD (dihydropyrimidine dehydrogenase) dual inhibitor, was evaluated in three preclinical data sets in combination with a capecitabine-based chemotherapy as well as with S-1, and showed an impact on key pathway regulation and improvements in cytotoxicity of FU in vitro. Phase I studies are underway to explore the use of TAS-114 in combination with capecitabine, and separate studies examining the compound in combination with S-1. TAS-114 is being developed for potential use in treating solid tumors.
  • TAS-115, a dual inhibitor of hepatocyte and vascular endothelial growth factor receptors, suppressed prostate cancer cell proliferation and osteoclast differentiation following bone resportion. Additionally, the combination of hepatocyte growth facto
    '/>"/>

Contact: Kerry Sinclair
kerry.sinclair@gcihealth.com
310-967-2952
GCI Health
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Medical care presents update on pharmaceutical health services research
2. Scientists use sound waves to levitate liquids, improve pharmaceuticals
3. Pharmica Consulting to Hold HIT Conference for the Pharmaceutical Industry
4. Is it constitutional for states to regulate pharmaceutical gifts and meals to doctors?
5. 5 more pharmaceutical companies join NIH initiative to speed therapeutic discovery
6. Nobel laureate to keynote international pharmaceutical conference at URI
7. MSU invention could help pharmaceutical industry save money
8. Global, common approach to pharmaceutical supply chain integrity the focus of workshop
9. 'EMT Exam Ace' Unveils Free Sample EMT Practice Quizzes
10. DRE Medical Equipment Unveils FX-300+ Surgical Headlight and Light Source
11. CustomerCentric Selling® Unveils New Client Testimonial Videos to Showcase Significant Sales Success
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... (PRWEB) May 23, 2013 Studies show that ... times per week are less likely to be overweight, less ... perform better academically, and have better relationships with their parents. ... in danger, according to family dinner expert and advocate ... have declined by 33 percent. When families do eat together, ...
(Date:5/23/2013)... Santa Monica, CA (PRWEB) May 23, 2013 ... to announce that their condition specific remedies are now ... Rd., Laguna Niguel, CA 92677. The line of ... the Whole Foods Market Chain. , Represented by Brandstorm ... available in Whole Foods Markets throughout California, Nevada and ...
(Date:5/23/2013)... CA (PRWEB) May 23, 2013 Brad ... today announced that the already sizzling Palm Springs ... boost thanks to the immense popularity of the Annual ... Museum on Monday, May 27, 2013. , Culminating the ... day of programs and events along with flight exhibitions. ...
(Date:5/23/2013)... Antonio, Texas (PRWEB) May 23, 2013 ... into their daily routines, Walkingspree is pleased to ... with Fitbit pedometer devices. This new upgrade ... Walkingspree dashboard members use to track their company’s ... and chart calories and fat burned. , Walkingspree ...
(Date:5/23/2013)... 23, 2013 FindUrgentCare.com launched updates to ... search option for patients. The new advanced feature ... including payment preferences, offered services, insurances accepted and hours ... way to narrow their search and receive targeted results ... provide ambulatory care to walk-in patients in a non-emergency, ...
Breaking Medicine News(10 mins):Health News:Family Dinner Expert and Cookbook Author Announces “Family Dinner Challenge” 2Health News:Dr. Garber's Natural Solutions Now Available at Whole Foods Market, Laguna Niguel, CA 2Health News:Annual Memorial Day Flower Drop Honors Veterans in Palm Springs California by Brad Schmett 2Health News:Walkingspree Expands Device Options with Fitbit to Increase Member Engagement in Corporate Wellness Programs 2Health News:Walkingspree Expands Device Options with Fitbit to Increase Member Engagement in Corporate Wellness Programs 3Health News:Find Urgent Care Launches New Site Design and Functionality to Provide Advanced Search Options for Users in Need of an Urgent Care Clinic 2Health News:Find Urgent Care Launches New Site Design and Functionality to Provide Advanced Search Options for Users in Need of an Urgent Care Clinic 3
... and Peru are working towards developing a vaccine against ... assassin bug. It is found to infect an estimated ... thousands each year. ,To date, no vaccine ... includes Trypanosoma cruzi — the causative agent of Chagas ...
... type 2 (AAV2) can kill cancer cells of cervical, breast, ... conditions. ,Penn State College of Medicine researchers who had ... of cancer cells and yet is not known to cause ... virus type 2 resides harmlessly in the human body and ...
... profiles and functional analyses of Wnt-related genes// in human joint ... Journal of Pathology. The article revolves around the protein, Wnt. ... to cancer in various organs. But current evidence might show ... ,At present a through analysis of the Wnt gene family ...
... Scientists have reported that the incidence of leukemia and infections ... cells. ,Stem cells are undifferentiated cells that have ... of specialized cells types that may form various types of ... ,Researchers working in the Stanford University School of Medicine have ...
... scientists have reportedly succeeded in generating sperm// and ovarian ... Center for Stem Cell Biology in Sheffield said that ... produce sperm and eggs to use in assisted conception ... couples with infertility. This research will allow embryonic stem ...
... diagnosed for diabetes type 2 may have increased risk ... the disease. ,A study done by the researchers ... among the children who are newly diagnosed for diabetes ... have showed tendencies of being afflicted by psychiatric illness ...
Cached Medicine News:Health News:Arthritis and the Wnt Factor 2
(Date:5/22/2013)... , May 22, 2013 Advanced Prenatal ... medical device that will help alleviate the high blood ... apheresis cartridge is expected to be the first medical ... of maternal and fetal death. Every year, ... the United States . It is characterized by ...
(Date:5/22/2013)... 22, 2013 /PRNewswire-iReach/ -- World markets are constantly ... latest trends and events, companies now need a ... an industry is headed next, so that they ... http://photos.prnewswire.com/prnh/20130522/CG19099 ) Global Information ... publisher GlobalData, offer decision makers and executives integrated ...
(Date:5/22/2013)... 2013  Viral hepatitis is an asymptomatic disease affecting more ... with hepatitis C are unaware they have the virus. ... in the U.S. House of Representatives will take place at ... the Rayburn House Office Building in Washington, D.C. ... Study of Liver Diseases ( AASLD ) is pleased to ...
Breaking Medicine Technology:Advanced Prenatal Therapeutics - Using Targeted Apheresis to Treat Preeclampsia 2Adapt, React, Evolve: Staying Ahead in the Breast Cancer Gene Testing, Solar Energy, and Oil & Gas Markets with Reliable Analytics and Actionable Insights from GlobalData's 700 Market Analysts 2Adapt, React, Evolve: Staying Ahead in the Breast Cancer Gene Testing, Solar Energy, and Oil & Gas Markets with Reliable Analytics and Actionable Insights from GlobalData's 700 Market Analysts 3Adapt, React, Evolve: Staying Ahead in the Breast Cancer Gene Testing, Solar Energy, and Oil & Gas Markets with Reliable Analytics and Actionable Insights from GlobalData's 700 Market Analysts 4Hepatitis Awareness: Bringing Attention to a Silent Epidemic 2
... The ACCU-Beam® line of Surgical ... beam splitters, objective lenses, fiber optic ... Surgical Microscope Dual Adaptor allows the ... quality images through either video or ...
... Femoral Compression System consists of a ... FemoStop Femoral Compression System.,Both devices work ... Hemostatic Dressing achieves topical hemostasis by ... while FemoStop Femoral Compression System provides ...
... has been specifically designed to ... perform safe and successful wavefront ... components such as the user ... been optimized to work in ...
... Absolute precision demands absolute ... Bausch & Lomb Zyoptix Diagnostic ... Zywave II Wavefront Aberrometer and ... System. Individually they supply critically ...
Medicine Products: