Navigation Links
Taiho Pharmaceutical unveils data on 8 novel anticancer compounds
Date:11/6/2012

colorectal cancer. Taiho took the encouraging results from this Phase II study and completed the required western Phase I studies to initiate a global Phase III program within a 15 month period.

Exploring New Treatment Options Alone and in Combination

Taiho has established a seamlessly connected research network, consisting of Tsukuba Research Center, Tokushima Research Center, the Taiho Clinical Development Center, and Taiho Pharma USA. The integrated network supports the discovery and development of numerous treatments. The Company's research achieves the highest standards of drug discovery by letting science guide its development path, and then applying modern technology and innovation to achieve that end. Investigational drugs stemming from this research are being examined as potential stand-alone products, or ones that can be used in combination with existing therapies to potentially enhance the safety and efficacy profile of current cancer options.

Highlights of the preclinical results of Taiho's investigational drugs being presented at the EORTC-NCI-AACR Symposium include:

  • TAS-114, a first-in-class dUTPase (deoxyuridine 5'-triphosphate nucleotidehydrolase) and DPD (dihydropyrimidine dehydrogenase) dual inhibitor, was evaluated in three preclinical data sets in combination with a capecitabine-based chemotherapy as well as with S-1, and showed an impact on key pathway regulation and improvements in cytotoxicity of FU in vitro. Phase I studies are underway to explore the use of TAS-114 in combination with capecitabine, and separate studies examining the compound in combination with S-1. TAS-114 is being developed for potential use in treating solid tumors.
  • TAS-115, a dual inhibitor of hepatocyte and vascular endothelial growth factor receptors, suppressed prostate cancer cell proliferation and osteoclast differentiation following bone resportion. Additionally, the combination of hepatocyte growth facto
    '/>"/>

Contact: Kerry Sinclair
kerry.sinclair@gcihealth.com
310-967-2952
GCI Health
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Medical care presents update on pharmaceutical health services research
2. Scientists use sound waves to levitate liquids, improve pharmaceuticals
3. Pharmica Consulting to Hold HIT Conference for the Pharmaceutical Industry
4. Is it constitutional for states to regulate pharmaceutical gifts and meals to doctors?
5. 5 more pharmaceutical companies join NIH initiative to speed therapeutic discovery
6. Nobel laureate to keynote international pharmaceutical conference at URI
7. MSU invention could help pharmaceutical industry save money
8. Global, common approach to pharmaceutical supply chain integrity the focus of workshop
9. 'EMT Exam Ace' Unveils Free Sample EMT Practice Quizzes
10. DRE Medical Equipment Unveils FX-300+ Surgical Headlight and Light Source
11. CustomerCentric Selling® Unveils New Client Testimonial Videos to Showcase Significant Sales Success
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2014)... Locks-Magnetic.com, a notable magnetic locks maker, has ... new products are available at low rates up to ... of the new emergency doors. The emergency door adopts ... choose from several colors. All of the products are ... release is not as easy as many people think. ...
(Date:11/23/2014)... AngelWeddingDress.com has recently updated its ... beach wedding dresses. “If you are looking for gorgeous ... soon as possible. Here you can enjoy 70% off ... , Holding a big marriage ceremony is the most ... beach wedding dress is uppermost priority. Ophelia, one of ...
(Date:11/23/2014)... November 23, 2014 Wright & Schulte ... of Ohio and West Virginia residents who allege that ... health disorders due to drinking C8 contaminated water ... West Virginia. According to the C8 complaints, the plaintiffs ... worked or lived in at least one of the ...
(Date:11/22/2014)... (PRWEB) November 23, 2014 Cancer researchers ... a connection between intercellular communication tunnels and the growth ... the full story on the Surviving Mesothelioma website. ... and the University of Minnesota have just released their ... information and materials between cells. They found that ...
(Date:11/22/2014)... 2014 BambooFlooringChina.com is a famous ... proudly released its new collection of bamboo mats ; ... to 29% off. , According to the sales ... grass, making it a highly renewable resource. Their bamboo mats ... mixing color which comes from natural bamboo with caramel bamboo ...
Breaking Medicine News(10 mins):Health News:Beach Wedding Dresses Added to Outstanding Online Dress Company AngelWeddingDress.com 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 3Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 4Health News:Study Links Cellular ‘Tunnels’ to Mesothelioma Proliferation, According to Surviving Mesothelioma 2Health News:Trendy Bamboo Mats Online Now By BambooFlooringChina.com 2
... One in eight parents reported that his or ... laboratory testing and/or appointments with specialists during the ... payment, according to a study, presented Sunday, Oct. 3, ... and Exhibition in San Francisco. For the ...
... , FRIDAY, Oct. 1 (HealthDay News) -- Doctors who take ... lifestyle habits to their patients than doctors who gobble down ... hit the gym, according to new research. Additionally, the ... they,d been well-trained to counsel their patients on lifestyle changes ...
... identify obscure cartoon characters than the native plants and animals ... connection to the natural world can have a profound impact ... author who coined the phrase, "nature-deficit disorder," will address this ... Pediatrics (AAP) National Conference & Exhibition Saturday, Oct. 2. His ...
... department at a mid-sized hospital were able to increase ... for measuring general technologist productivity, according to a study ... American College of Radiology ( www.jacr.org ). ... priorities that may be difficult to achieve simultaneously," said ...
... Johns Hopkins scientists have discovered a way to turn off ... mice, a discovery that could have implications for the millions ... peanuts and milk. The findings, published online in the ... could be trained to tolerate food allergies that lead to ...
... review article published in the October issue of ... Clinic physicians differentiate the ethical and legal permissibility ... comfort measures, specifically palliative sedation, from that of ... that palliative sedation has an important place on ...
Cached Medicine News:Health News:1 in 8 parents forgoes pediatrician-recommended care 2Health News:Doctors' Health, Well-Being Affect Patient Counseling 2Health News:Doctors' Health, Well-Being Affect Patient Counseling 3Health News:Johns Hopkins researchers turn off severe food allergies in mice 2
(Date:11/21/2014)... DUBLIN, Ohio and MELVILLE, N.Y. ... (NYSE: CAH ), one of the world,s ... (NASDAQ: HSIC ), the world,s largest provider ... animal health and medical practitioners, today announced that the ... provide one of the most comprehensive service and product ...
(Date:11/21/2014)... Nov. 20, 2014  RedRick Technologies, a provider ... reading room environment guidance, has helped the new ... reading room, which may also serve as a ... Medicine. "In line with the ... of Radiology,s Imaging 3.0 ™ initiative, the ...
(Date:11/21/2014)... 20, 2014 Depomed, Inc. (NASDAQ: DEPO ) ... 26 th Annual Healthcare Conference in New York ... conference is scheduled for 8:00 am EST (5:00 am PST) on ... webcast can be accessed via the Investor Relations page of the ... will be archived for 30 days on the company,s website. ...
Breaking Medicine Technology:Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 2Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 3Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 4Cardinal Health And Henry Schein Enter Into Long-Term Strategic Agreement To Serve Physician Offices 5RedRick Technologies Helps Penn Radiology Implement New Radiology Reading Room Concepts 2RedRick Technologies Helps Penn Radiology Implement New Radiology Reading Room Concepts 3Depomed To Present At Piper Jaffray 26th Annual Healthcare Conference 2
... DALLAS, Nov. 1 Death resulting from,influenza, often referred ... heart disease than among patients with any other chronic ... heart disease,patients conducted by Harris Interactive on behalf of ... with the American Heart,Association (AHA), more than one in ...
... The U.S. Department of,Health and Human Services (HHS), ... of Health of the United Mexican States today ... surveillance,prevention, and control of infectious diseases for the ... of their peoples. The Memorandum of Understanding ...
Cached Medicine Technology:Despite Serious Health Risks, One in Three Adults with Heart Disease Does Not Believe They Need a Flu Shot This Year 2Despite Serious Health Risks, One in Three Adults with Heart Disease Does Not Believe They Need a Flu Shot This Year 3Despite Serious Health Risks, One in Three Adults with Heart Disease Does Not Believe They Need a Flu Shot This Year 4United States, Canada and Mexico Agree to Mutual Assistance During Public Health Emergencies 2
DePuy 2 Bone Cement is a unique fast-set digital cement that is the excellent choice for small joint procedures such as the patella, glenoid or other extremity joints....
... Sir John Charnley and CMW, Inc. ... develop bone cements exclusively for orthopaedic ... 40 years of performance and excellence ... offers one of the first proven ...
... Blood Flow Analyzer is a fast, clinically ... diagnosis of low and normal-tension glaucoma., ,The ... fast, clinically proven measurement that improves detection ... the management of glaucoma, and detection of ...
Occu-Flo Plugs Offer: , Easy Insertion , A polished, smooth, transparent finish which creates immediate patient comfort and adaptation , High tolerance by patients , No discomfort should removal be ...
Medicine Products: