Navigation Links
Tafamidis: Approval denotes proven added benefit
Date:4/5/2012

rove the quality of life, for instance the treatment of pain in polyneuropathy with other drugs (e.g. amitriptyline, gabapentin).

Positive effect in neurological disorders only limited

Only one of the two relevant studies (Fx-005) provided reliable data - and only for patients with a particular genetic defect (Val30Met). The second study (Fx1A-201) in adults with different genetic defects was not controlled, i.e. here the effect of tafamidis was not directly compared with another treatment. It remains unclear how the results of the reliable study can be applied to the patients with genetic defects other than Val30Met.

Assessment of the study data according to the methods of IQWiG produced a hint of a positive effect of tafamidis in respect of the progression of nerve damage. However the effect was only minor.

With regard to other patient-relevant outcomes (other symptoms and side effects, mortality, quality of life), the Institute was unable to identify any further statistically significant advantages or disadvantages of tafamidis compared with the comparator treatment.

G-BA decides on the extent of added benefit

The dossier assessment is part of the overall procedure for early benefit assessment conducted by the G-BA. After publication of the manufacturer's dossier and its assessment by IQWiG, the G-BA initiates a formal commenting procedure which provides further information and can result in a change to the benefit assessment. The G-BA then decides on the extent of the added benefit, thus completing the early benefit assessment.


'/>"/>

Contact: Anna-Sabine Ernst
presse@iqwig.de
49-022-135-6850
Institute for Quality and Efficiency in Health Care
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Neuralstems NSI-189 trial in major depressive disorder receives FDA approval to advance to Phase Ib
2. FDA Revokes Approval of Avastin for Breast Cancer
3. St. Michaels echocardiology lab awarded international seal of approval
4. Mayo Clinic receives FDA approval for ovarian and breast cancer vaccines
5. Pioneering stem cell bandage receives approval for clinical trial
6. FDA predictability a top concern for medtech firms; EU preferred for product approval
7. New Hepatitis C Drugs Close to Gaining FDA Approval
8. New Hepatitis C Drug Close to Gaining FDA Approval
9. Sanofi Pasteur announces FDA approval of menactra meningococcal conjugate vaccine indication for infants
10. FDA approval of brain aneurysm device gives Jefferson neurosurgeons another life-saving tool
11. Novel immunotherapy drug receives FDA approval for the treatment of metastatic melanoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... CA (PRWEB) April 24, 2015 On ... sitting down in an interview with ItsNotAboutMe.TV contributor Karen ... Recovery, a holistic treatment center for addiction, of which ... ceremonies and festivals throughout the year, the EcoLuxe Lounge ... providers of eco-friendly and socially conscious products and services. ...
(Date:4/24/2015)... Carinsurancequotesinfo.com has released a new blog post has ... qualify for auto insurance as a single parent. ... online, without having to follow a special process. The ... reduce their auto insurance expenses. The tips are presented ... , Clients can now visit an insurance brokerage website ...
(Date:4/24/2015)... Vancouver, BC (PRWEB) April 24, 2015 ... Albert Yuzpe, Olive Fertility co-founder and co-director, has been ... Fertility Preservation at the Evening of Hope Gala. ... to recognize Dr. Albert Yuzpe, who has been at ... past 43 years,” says Jessica Séguin, Executive Director of ...
(Date:4/24/2015)... Insuranceautoquote.info has released a new blog ... . , Lowering auto insurance prices is not ... find better offers for their financial budget. Comparing prices ... not require any registration. , Comparing quotes can ... multiple agencies that sell coverage and this means that ...
(Date:4/24/2015)... 24, 2015 “ Opera ” was featured ... features the latest and coolest technology products available to consumers. ... conducted the review and shared with viewers how this is ... browsers, surfing the internet would not be in existence. But ... the Opera browser is no different. Celebrating their 20th anniversary ...
Breaking Medicine News(10 mins):Health News:Karen Salkin Talks with Per Wickstrom at the 2015 EcoLuxe Lounge and the "Salute to the Oscars" Celebration 2Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2Health News:Olive Fertility Centre Co-founder, Dr Al Yuzpe, Recognized as a Pioneer in Fertility Preservation 2Health News:Car Insurance Quotes Can Help Drivers Lower Their Premiums 2Health News:A Web Browser That Connects over 350 Million People was Featured on NewsWatch Television 2
... N.Y. -- Increases in young womens drinking during the ... college can have dangerous physical, sexual and psychological implications, ... Buffalos Research Institute on Addictions. , The good news ... many young women increase their drinking, the majority (78 ...
... Despite Difficulties, States Rise Against the Status Quo ... - A new report from the,Robert Wood Johnson ... 2008: Rising to the Challenge, outlines 2007 efforts ... to address health care,reform at the state level. ...
... Feb. 8 Corbett Worldwide Healthcare,Communications launched a ... glimpse of how the Chicago agency combines passion, ... soar. The new site was announced,today at the ... http://www.newscom.com/cgi-bin/prnh/20080208/AQF005 ), "Our Web site reflects ...
... Study finds spouses die sooner in unions where anger is ... the secret to a long marriage is communication, and new ... life. , A lengthy study of Midwestern couples finds that ... than the perennially resentful. The couples with the most unexpressed ...
... be the only one if its kind in the ... Cancer Care Alliance (SCCA),and Northwest Hospital & Medical Center ... explore the development of a new, state-of-the-art,cancer treatment facility ... its intention to develop a proton-therapy,facility in September 2006 ...
... Symmetry Medical Inc.,(NYSE: SMA ), a leading ... and other medical markets, today announced it,will provide a ... 14, 2008 before the opening of the U.S. financial ... 8:00 a.m. ET on,February 14, 2008., A live ...
Cached Medicine News:Health News:A dangerous transition: High school to the first year of college 2Health News:A dangerous transition: High school to the first year of college 3Health News:A dangerous transition: High school to the first year of college 4Health News:Report Lists Key Policy Questions Facing State, National Health Reform 2Health News:Report Lists Key Policy Questions Facing State, National Health Reform 3Health News:Report Lists Key Policy Questions Facing State, National Health Reform 4Health News:Corbett Worldwide Healthcare Communications' New Web Site Demonstrates How Fresh Ideas 'Blow In' From Chicago 2Health News:Mutual Resentment in Marriage Can Be Deadly 2Health News:Mutual Resentment in Marriage Can Be Deadly 3Health News:Seattle Cancer Care Alliance and Northwest Hospital Sign Letter of Intent to Develop Proton Therapy Center for Cancer Treatment 2Health News:Seattle Cancer Care Alliance and Northwest Hospital Sign Letter of Intent to Develop Proton Therapy Center for Cancer Treatment 3Health News:Symmetry Medical to Provide Fourth Quarter 2007 General Business Update on February 14, 2008 2
(Date:4/24/2015)... Spain , April 24, 2015  Elekta has ... Monaco® treatment planning system , enabling European clinics ... supports major treatment techniques including advanced 3D planning, IMRT, ... system. Monaco ... as well improved workflow efficiency. Advancements in 3D planning ...
(Date:4/23/2015)... 2015  ResMed Inc. (NYSE: RMD ) today ... Revenue for the quarter was $422.5 million, a 6 ... 2014 (a 13 percent increase on a constant currency ... 1 percent compared to the quarter ended March 31, ... $0.64, an increase of 2 percent compared to the ...
(Date:4/23/2015)... , April 23, 2015 Nektar Therapeutics (Nasdaq: ... first quarter ended March 31, 2015 on Thursday, April 30, ... Robin , president and chief executive officer, will host a ... Eastern Time (ET)/2:00 p.m. Pacific Time (PT). ... conference call can be accessed through a link that is ...
Breaking Medicine Technology:Elekta CE marks for Monaco v5.10 treatment planning system 2ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 2ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 3ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 4ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 5ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 6ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 7ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 8ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 9ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 10ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 11ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 12ResMed Inc. Announces Results for the Third Quarter of Fiscal Year 2015 13Nektar to Announce Financial Results for the First Quarter 2015 on Thursday, April 30, 2015, After Close of U.S.-Based Financial Markets 2
... SAN FRANCISCO, Calif., Nov. 9 Anesiva, Inc. (Nasdaq: ... received a letter from The NASDAQ Stock Market LLC ("Nasdaq") ... for continued listing on The NASDAQ Global Market subject to ... December 31, 2009, the proposed merger (the "Merger") contemplated by ...
... Nov. 7 Patients reported C1-esterase inhibitor (C1-INH) concentrate ... at any body location for HAE, a rare and ... the 2009 American College of Allergy, Asthma & Immunology ... survey of patients conducted in parallel with the ongoing, ...
Cached Medicine Technology:Anesiva Receives Positive Nasdaq Hearing Panel Determination for Continued Listing 2Anesiva Receives Positive Nasdaq Hearing Panel Determination for Continued Listing 3Hereditary Angioedema Patients Report: C1-Esterase Inhibitor Concentrate Effective in Treating Acute Attacks, Helps Them Avoid Emergency Care 2Hereditary Angioedema Patients Report: C1-Esterase Inhibitor Concentrate Effective in Treating Acute Attacks, Helps Them Avoid Emergency Care 3
50L...
... precision, ergonomics, and value!, Comfortable ... soft non-slip, contoured handle , Finer ... plunger spring action , Completely autoclavable ... the need for recalibration , Easy-to-read ...
... Series 2000 Pipette is a synonym for ... and robust design, and superior operating comfort. ... operate the measuring stroke and blow-out as ... "pipette/tip" system ensures utmost accuracy and precision. ...
250L...
Medicine Products: