Navigation Links
Tadalafil shows promise for relief of lower urinary tract symptoms associated with BPH
Date:8/18/2008

New York, August 19, 2008 Men with signs of benign prostatic hyperplasia (BPH) can be helped with a daily dose of erectile dysfunction drug tadalafil (Cialis) to relieve associated lower urinary tract symptoms (LUTS), according to a new study published in the October 2008 issue of The Journal of Urology. Researchers from the University of Texas Southwestern Medical Center at Dallas, Northwestern University and Lilly Research Laboratories report on a randomized, double-blind, placebo-controlled study of over 1000 men in ten countries.

Claus G. Roehrborn, MD, Professor of Urology, University of Texas Southwestern Medical Center, states, "Since reports of erectile dysfunction (ED) incidence, pathophysiology and treatment have shown a possible link between BPH LUTS and ED. PDE5 inhibitors like tadalafil (Cialis) have received increased attention for treating BPH LUTS, although they are currently only approved for ED. The half-life of tadalafil is 17.5 hours, making it suitable as once daily therapy. Although the precise mechanism of action by which PDE5 inhibitors may alleviate LUTS is not completely understood, several putative mechanisms are currently under investigation."

Men with signs of BPH may experience LUTS, such as urinary frequency, urgency, intermittence, nocturia, straining, incomplete emptying or a weak urinary stream. LUTS increase with age with an overall prevalence of greater than 50% in men 50 years or older. Drugs currently used to treat these symptoms can produce unwanted side effects, including dizziness, low blood pressure and sexual dysfunction.

Participants in the tadalafil study were required to have at least a 6-month history of LUTS secondary to BPH. Subjects with a high PSA (more than 10 ng/ml) were excluded, as were subjects with other complicating conditions or conflicting drug treatments. Anyone who had undergone treatment for erectile dysfunction or other BPH treatments underwent a 4-week treatment
'/>"/>

Contact: Linda Gruner
l.gruner@elsevier.com
212-633-3923
Elsevier Health Sciences
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. FDA Approves Cialis(R) (tadalafil) for Once Daily Use for the Treatment of Erectile Dysfunction
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. New research shows how chronic stress worsens neurodegenerative disease course
4. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
5. Circulating fats kill transplanted pancreas cells, study shows
6. New Heart Pump Shows Promise in Trial
7. Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
8. New Survey Shows Americans are Still Concerned About Food Safety, Yet Still Not Smart About What They Like to Eat
9. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
10. Amid Improving Life Expectancy Rates, Risk of Premature Death is Still Significant for Americans, New Study Shows
11. Avocados may help prevent oral cancer, OSU study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/18/2013)... The use of a smartphone application significantly ... new research presented today at Digestive Disease Week ... advance of the procedure, includes dietary restrictions and ... at strict intervals. The better the preparation, the ... and precancerous polyps in the colon. The study, ...
(Date:5/18/2013)... Assisted living and retirement communities have ... comfort of their residents. Systems Technologies is well-acquainted ... effective and cost-efficient solution – VisionLink Wireless Nurse ... communications solution that helps nurses provide the highest ... privacy. , The VisionLink nurse call ...
(Date:5/18/2013)... 2013 The Communities of Distinction TV ... we call home. These are the townships, villages and other ... locations where the people are friendly and neighbors are there ... the highways and shares the best in both the United ... an American sports and film celebrity. It airs in May ...
(Date:5/18/2013)... (PRWEB) May 18, 2013 TheBeautyPlace.com answers ... Pattern hair loss is not a result of stress, ... to Men’s Fitness Magazine, 70% of men suffer from ... Strength is renowned for hair transplant surgery, but ... male pattern baldness known as Bosley Professional Strength. Their ...
(Date:5/18/2013)... 18, 2013 Although obesity is associated ... association between obesity and esophageal adenocarcinoma, a type of ... tumors. As reported on Cancer.gov, last reviewed ... twice as likely as those of normal and healthy ... between obesity and esophageal cancer is not well understood, ...
Breaking Medicine News(10 mins):Health News:New smartphone application improves colonoscopy preparation 2Health News:VisionLink Nurse Call System's New Features Serve the Unique Needs of Retirement Communities 2Health News:VisionLink Nurse Call System's New Features Serve the Unique Needs of Retirement Communities 3Health News:Communities of Distinction TV Presents "A Place to Call Home" Segment 2Health News:TheBeautyPlace.com Features the Two New Best-Selling Hairloss Products: Bosley Professional Strength and Nioxin Systems 2Health News:TheBeautyPlace.com Features the Two New Best-Selling Hairloss Products: Bosley Professional Strength and Nioxin Systems 3Health News:hCGtreatments / Diet Doc Hcg Diets & Weight Loss Plans Announces New Prescription Hcg Diet Plans Designed to Trim Inches and Thus Reduce the Risk of Esophageal Cancer 2Health News:hCGtreatments / Diet Doc Hcg Diets & Weight Loss Plans Announces New Prescription Hcg Diet Plans Designed to Trim Inches and Thus Reduce the Risk of Esophageal Cancer 3
... kidney failure in men.// ,The researchers had taken 473 ... a glass a day) and compared their elevated creatinine levels ... than a glass a day of alcohol. The research had ... through a period of 14 years. ,The results of ...
... UCLA had been able to isolate a biomarker for prostate ... the disease. ,The biomarker protein, which was hidden inside ... from where it can go into the blood. This will ... prostate cancer disease with both chemotherapy and immunotherapy, for better ...
... been associated to cardiovascular diseases and recent study says that// ... have always been carried on to find out the effect ... new study was done to find out the effect of ... ,In cocaine users undergoing coronary angiography, there was evidence of ...
... scan reports have suggested that a new gene may ... depression. ,People having the gene that controls depression ... the mood regulating circuit. This gene may be affecting ... the emotion of fear, and cingulated, another part of ...
... in man, a disease called AIDS.// Scientists are now convinced ... do fight back against the virus. ,The new research, ... a small amount of body’s antibodies are successful in fighting ... extent. ,Till date the treatment of AIDS had ...
... the blood can increase the risk of having testicular cancer ... of British Journal of Cancer says that the increase in ... by almost as much as 4.5 % than for people ... from Karolinska University Hospital had looked into the data of ...
Cached Medicine News:
(Date:5/17/2013)... today announced that it will report its 2013 first quarter earnings on ... Ed Borkowski , CFO, will host an analyst and ... To participate in the conference call within the U.S. and ... conference call outside the U.S. and Canada , dial ... Participants should dial in 10 minutes prior to the start of the ...
(Date:5/17/2013)... 17, 2013 Fuse Science, Inc. (OTCQB: DROP), ( ... is developing new, patent-pending technologies poised to redefine how consumers ... will hold a business update teleconference and webcast for shareholders ... 2013 at 4:30 PM ET. Fuse Science, ... the call and will be joined by Rubin ...
(Date:5/17/2013)... SEATTLE , May 17, 2013  Atossa Genetics, Inc. ... today that Kyle Guse , Chief Financial ... Marcum LLP MicroCap Conference on Thursday, May 30, 2013, in ... Hyatt Hotel. The Company,s presentation is scheduled ... via a live webcast. To access the webcast, go to ...
Breaking Medicine Technology:Fuse Science, Inc. to Hold Business Update Webcast and Teleconference on May 22nd 2Atossa Genetics to Present at the Second Annual Marcum LLP MicroCap Conference 2Atossa Genetics to Present at the Second Annual Marcum LLP MicroCap Conference 3
The SportStat Pulse Oximeter shines red and infrared light through a finger and detects the fluctuating signals caused by blood flow. Pulse rate is determined from the signals received by a light det...
The reliable and easy-to-use 3900/P pulse oximeter is now more advanced - featuring TruTrak+ technology, the proprietary clinical motion algorithm from Datex+-Ohmeda....
... The Invacare Digital Pulse ... and pulse strength. It is ... measurements on challenging patients. The ... other artifacts, informs the operator ...
... The 8600FO is designed ... of MRI users for patient ... Nonin;s Fiber Optic Sensors and ... burns is eliminated, as well ...
Medicine Products: