Navigation Links
TGen analysis identifies biomarkers for diabetic kidney failure
Date:12/30/2009

ic DNA from more than 500 cases of those with ESRD and compared that to more than 500 patients who had Type I diabetes for at least 20 years with no sign of ESRD. Scientists performed a whole genome association scan to look for single nucleotide polymorphisms (SNPs), which are the individual letters of DNA that vary among individuals. They sought SNPs that indicate a susceptibility to ESRD.

Experiments identified at least eight locations along the nearly 3-billion-base human genome that are ripe for further investigation of their ties to ESRD, according to the paper, Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetes.

The study found at least six markers that may be associated with Type 1 diabetes, a lifelong disease that occurs when the pancreas does not produce enough insulin to properly control blood-sugar levels. There currently is no way to prevent Type 1, which is caused by autoimmune, genetic or environmental factors.

The study found two markers that may be associated with Type 2 diabetes, the most common form of diabetes. Type 2 develops when the body fails to produce enough insulin, which helps turn glucose from the sugars and starches we eat into energy. The failure to process glucose starves cells of energy and over time can damage the eyes, nerves, heart or kidneys. Type 2 diabetes can be prevented or treated with proper diet and exercise.

Using a similar pooled DNA analysis, TGen researchers, working with collaborators at the University of California Los Angeles, last year developed a way to identify an individual's DNA from among a mixture of DNA of hundreds or even thousands of individuals.

"This technique will increasingly be used in identifying the genetic origins of many Types of disease,'' predicted Dr. David Craig, Associate Director of TGen's Neurogenomics Division, who co-developed the tech
'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. Latest DES Analysis Stresses Importance of Physicians Well-Trained in Implantation Technique and Patient Follow-Up
3. Consumer Reports Analysis: Drugs for Nerve Pain, Fibromyalgia Effective, But Not Always Best
4. Takeda statement on ACTOS meta-analysis published in the Journal of the American Medical Association
5. Takeda Statement on ACTOS(R) (Pioglitazone HCl) Meta-Analysis Published in the Journal of the American Medical Association
6. Physical Therapist Provides Injury Analysis for Fantasy Football
7. Sanofi-Aventis renews licenses for Genomatix chip analysis pipeline
8. Meta-Analysis of Blood Phe Levels and Clinical Outcomes in PKU Published
9. OCS and Press Ganey Partner to Create Joint Analysis of Outcomes and Satisfaction
10. New Analysis Underscores Legality of Physician Ranking and Public Reporting Systems When Used by Health Insurers to Improve Health Care Quality
11. Barta joins Conseco as Senior Vice President, Financial Planning & Analysis; Barra named Senior Vice President, Internal Audit; Clarke to head Investor Relations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... WI (PRWEB) September 22, 2014 ... in the United States, promotes National Self-Improvement ... believes that all individuals should have access to ... in aging. , The demand for products that ... longer than ever before. For over six years, ...
(Date:9/22/2014)... Va. (PRWEB) September 22, 2014 ... the nation’s leading nonprofit authority on the ... healthcare information exchange, announced findings from its recent ... Health Plan Identifier (HPID) within electronic transactions adopted ... (HIPAA). WEDI conducted the survey from August 20 ...
(Date:9/22/2014)... MONDAY, Sept. 22, 2014 (HealthDay News) -- Two new ... Administration (FDA) may provide some relief for people with ... to a new study. One device -- the ... other device -- the Cerena -- is meant to ... FDA news release. "Patients have been looking for ...
(Date:9/22/2014)... 22, 2014 Pain does not need to ... a user- and reader-friendly book designed to guide the individual ... living. This inspirational book is written to help the reader ... a way to regain a pain-free life — a daily ... pain. , Chronic pain has become an epidemic, with over ...
(Date:9/22/2014)... 22, 2014 PCI (Project Concern ... to equip women around the world with tools and ... the Women Empowered (WE) Initiative announced at the CGI ... groups to pool their savings, invest in their own ... solution to ending poverty in the world, and through ...
Breaking Medicine News(10 mins):Health News:Quincy Bioscience Promotes National Self-Improvement Month 2Health News:WEDI Announces Survey Results from Unique Health Plan Identifier (HPID) Industry Poll 2Health News:WEDI Announces Survey Results from Unique Health Plan Identifier (HPID) Industry Poll 3Health News:Noninvasive Devices May Help Migraines, FDA Says 2Health News:Naturopathic Doctor Inspires and Guides Those Who Suffer with Chronic Pain, Pointing the Way Back to Pain-free Living 2Health News:PCI Announces New Effort to Empower 250,000 Women Worldwide at 2014 Clinton Global Initiative (CGI) Annual Meeting 2Health News:PCI Announces New Effort to Empower 250,000 Women Worldwide at 2014 Clinton Global Initiative (CGI) Annual Meeting 3
... a young Indian American is hard put to find a ... South Asians are listed in the US Bone Marrow registry. ... a disease known as Acute Myelogenous Leukemia (or AML), a ... Asian community has come together nationwide to help him and ...
... International Diabetes Federation (IDF) today called for projects that ... with diabetes and to implement practical solutions for improving ... as BRIDGES (Bringing Research in Diabetes to Global Environments ... Congress in Cape Town, South Africa and was officially ...
... ice sheet to break up, even though the air over ... at least a century, according to a new study ... ,As part of their study, the team led by ... how high the ice had deposited boulders in Antarctica's Framnes ...
... Echinacea, a medicinal herb that came to prominence thanks to its ... catching a cold, a wide-scale study has confirmed. ,Taking ... percent and may also shorten the duration of a cold almost ... Sunday in the July issue of the journal The Lancet Infectious ...
... studies have found that new adjuvant treatments for breast ... Published in the August 1, 2007 issue of Cancer, ... studies looked at the cost-effectiveness of different drugs for ... ,In a Canadian economic study of estrogen ...
... Six World Heritage sites, including Mount Everest, could be at ... experts and groups . ,Urging the United Nations ... the Climate Justice Programme have petitioned the global body to ... that have signed the UN World Heritage Convention have a ...
Cached Medicine News:Health News:South Asians Seek Bone Marrow for Young Indian American 2Health News:The International Diabetes Federation Launches US$ 10 Million Grant to Improve Diabetes Care 2Health News:The International Diabetes Federation Launches US$ 10 Million Grant to Improve Diabetes Care 3Health News:Sioux Herb Confirmed as Shield Against Colds 2Health News:New Adjuvant Breast Cancer Treatments Found Cost-effective 2Health News:Everest, Five Other World Heritage Sites Face Climate Change Risk 2
(Date:9/22/2014)... , Sept. 22, 2014 /CNW/ - T-Bird Pharma ... focused on developing premium quality medical marijuana products, is ... Biomedical Inc. ("Thunderbird"), has signed a definitive lease agreement ... , BC.  The facility has 28,966 square feet ... 14,500 square feet of mezzanine space for a total ...
(Date:9/22/2014)... Pa. , Sept. 22, 2014  Inovio ... today it has initiated a phase I clinical ... will evaluate the safety, tolerability, and immunogenicity of ... (HPV-6), which causes most aerodigestive cancers. ... throat, vocal cords, and parts of the esophagus ...
(Date:9/22/2014)... NEW YORK , Sept. 22, ... has signed an exclusive, global license agreement with ... commercialization of its proprietary plasma fractionation process. Concurrently, ... and its intention to strategically refocus and rebrand ... plans to pursue a national listing for its ...
Breaking Medicine Technology:T-Bird Pharma Inc. to Increase Growing Capacity with Expansion into a 43,500 square feet Second Facility 2T-Bird Pharma Inc. to Increase Growing Capacity with Expansion into a 43,500 square feet Second Facility 3Inovio Pharmaceuticals Expands HPV Immunotherapy Development to Aerodigestive Cancers 2Inovio Pharmaceuticals Expands HPV Immunotherapy Development to Aerodigestive Cancers 3Inovio Pharmaceuticals Expands HPV Immunotherapy Development to Aerodigestive Cancers 4Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 2Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 3Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 4Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 5Access Pharmaceuticals Announces Exclusive Global Plasma Therapeutics License, New Management And New Corporate Name 6
... $300,000 as Title Sponsor of ZENPEP(R) CF Cycle for Life , ... BETHESDA, Md. , May 3 Thousands of cyclists will take ... tour in 18 cities across the country to support research to find new therapies and a ... San Francisco on June 26 . , ...
... American Pacific Corporation ( APFC) ("AMPAC") ... on Thursday, May 6, 2010 , immediately after the market closes, followed ... , , , ... invites you to participate in the teleconference to discuss the financial results ...
Cached Medicine Technology:Cystic Fibrosis Foundation Launches National Cycling Series to Benefit Critical Research and Care 2Cystic Fibrosis Foundation Launches National Cycling Series to Benefit Critical Research and Care 3American Pacific to Release Financial Results and Hold Fiscal 2010 Second Quarter Investor Teleconference 2
Indications For Usage: ,Airway management during anesthesia or short-term surgical procedures....
Indications For Usage: , When patient's head is in an extended or flexed position When patient will be turned over. , Long-term cases where maintenance of an airway is critical. , Neurosurgical pr...
Indications For Usage: ,Airway management during pediatric surgical procedures and intensive care....
... Detector/Clamp adds air detection and automatic clamping capability ... Fluid Warmer., ,The potential of air embolism ... known. Currently, health care professionals rely primarily on ... has lead to the safe use of the ...
Medicine Products: