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TGen Drug Development partners with Horizon Discovery for integrated personalized medicine service
Date:4/12/2010

SCOTTSDALE, Ariz., and Cambridge, U.K. April 12, 2010 A strategic alliance announced today between TGen Drug Development (TD2) and Horizon Discovery Limited will significant advance personalized medicine.

The partnership will create a beginning-to-end solution for pharmaceutical and biotechnology companies to more rationally design and tailor their drugs to specific patient populations based on the unique genetic variations that define a given disease.

TD2 will use Horizon's panel of more than 200 genetically-defined human isogenic cell-lines designed to accurately mirror cancer patient genetics in its comprehensive pre-clinical service as a prelude to performing selected in-house clinical trials. This will provide clients with a fully integrated drug discovery service that will accelerate the isolation and optimization of appropriately targeted therapeutic agents and attain their rapid market approval. And it will save time and money in the development of more effective cancer treatments.

"The future of oncology drug development will require us to predict which patients will respond to what drug," said Dr. Stephen Gately, TD2's President and Chief Scientific Officer, referring to the goal of personalized medicine treating patients with drugs tailor-made for their specific diseases.

"This partnership is the engine that will actually make this work and allow for the design of shorter and less-costly clinical trials that enroll the patients most likely to respond to a given drug," Gately said.

Today's agreement between TD2 and Horizon builds on another agreement announced Feb. 2 between Horizon and TD2's parent organization, the Translational Genomics Research Institute (TGen), to develop new human disease models for TGen's cancer research.

"Working with TD2 will enable us to broaden the impact of our GENESIS and X-MAN technologies in the quest for therapies that target the genetic causes of cancer in e
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Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

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