Navigation Links
TGen, Tecan and ASU Biodesign Institute develop sample preparation solution for proteomic research
Date:6/23/2011

PHOENIX, Ariz. June 23, 2011 A new automated sample preparation system based on Tecan's Freedom EVO 200 liquid handling platform has been developed for proteomic biomarker discovery and validation in collaboration with the Translational Genomics Research Institute (TGen) and the Biodesign Institute at Arizona State University.

The fully automated, integrated, high-throughput system is a key tool in the research institutes' goal of establishing an industrial-scale biomarker validation facility.

The platform can prepare nearly 1,000 samples in less than 24 hours in the SISCAPA (Stable Isotope Standards with Capture by Anti-Peptide Antibody) workflow, from receiving samples in cryovials, to eluting selected peptides into 96-well plates ready for analysis by mass spectrometry.

The scientific leadership for the integrated system specification and multi-vendor competition included: Dr. Konstantinos Petritis (TGen); and Dr. Mark Holl and Dr. Deirdre Meldrum (Biodesign Institute).

"During biomarker discovery, we work with 20 to 100 samples but, once we have identified potential biomarkers, verification and clinical validation must be performed, where the challenge is to process hundreds, perhaps thousands, of samples," said Dr. Petritis, Associate Professor and Laboratory Head at TGen's Center for Proteomics.

"One of Tecan's greatest strengths was undoubtedly the ease with which it seamlessly brought everything together. Sample preparation is a critical yet extremely long, multi-stage and labor-intensive process that must be performed reproducibly. The Tecan system is a comprehensive and flexible proteomic sample preparation platform that successfully integrates and controls many different modules from a range of vendors."


'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1

Related medicine news :

1. TGen, UA student-researcher extends string of coveted scholarships
2. Adding topotecan to standard treatment for ovarian cancer does not improve progression-free survival
3. Biodesign hosts international consortium on screening for lung cancer
4. Stanford Woods Institute awards Environmental Venture Projects
5. UC Riverside botanist receives high honor from Howard Hughes Medical Institute
6. Van Andel Research Institute finding is potential predictor of deadly cancer common in Asia
7. Crime Victims Institute studies adolescent sex and laws
8. NIH awards Salk Institute $5.5 million grant to study Williams syndrome
9. CHEO Research Institute develops secure protocol for data disclosure
10. Weizmann Institute scientists show: How adversity dulls our perceptions
11. Cryoablation used to successfully treat atrial fibrillation at the Montreal Heart Institute
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... , ... June 27, 2016 , ... TopConsumerReviews.com recently awarded ... Eyeglasses . , Millions of individuals in the United States and Canada wear ... a way to both correct vision and make a fashion statement. Even celebrities use ...
(Date:6/26/2016)... ... ... legally blind and certified personal trainer is helping to develop a weight loss fitness plan ... fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily ... of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures ... . Simply select a ProHand generator and drag it above media or text in ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... ... 2016 , ... The Pulmonary Hypertension Association (PHA) learned during ... two significant new grants to support its work to advance research and patient ... recognizing patients, medical professionals and scientists for their work in fighting pulmonary hypertension ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016 /PRNewswire/ ... pulmonary function testing company, is now able to perform sophisticated lung ... ndd Medical Technologies , Inc. Patients are ... labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients like ... any needed testing done in the comfort of her own home. ...
(Date:6/24/2016)... 24, 2016   Pulmatrix, Inc ., (NASDAQ: ... inhaled drugs, announced today that it was added to ... its comprehensive set of U.S. and global equity ... an important milestone for Pulmatrix," said Chief Executive Officer ... of our progress in developing drugs for crucial unmet ...
(Date:6/23/2016)... HOUSTON , June 23, 2016  MedSource ... platform as its e-clinical software solution of choice.  ... the best possible value to their clients by ... nowEDC.  The preferred relationship establishes nowEDC as the ... pricing for MedSource,s full-service clients.  "nowEDC has long ...
Breaking Medicine Technology: