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TAXUS(R) Liberte(TM) Drug-eluting Coronary Stent System Receives CE Mark for Use in Diabetic Patients
Date:12/21/2007

on Form 10-K filed with the Securities and Exchange Commission, which we may update in Part II, Item 1A - Risk Factors in Quarterly Reports on Form 10-Q we have filed or will file thereafter. We disclaim any intention or obligation to publicly update or revise any forward- looking statements to reflect any change in our expectations or in events, conditions, or circumstances on which those expectations may be based, or that may affect the likelihood that actual results will differ from those contained in the forward-looking statements. This cautionary statement is applicable to all forward-looking statements contained in this document.

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References

(1) For patients with concomitant diabetes mellitus.

(2) Ormiston J, Mahmud E, Mandinov L, et al. TAXUS Liberte attenuates the

risk of restenosis in diabetics: results from the TAXUS ATLAS Program.

Presented at the annual Transcatheter Cardiovascular Therapeutics

symposium, Washington, D.C., 20-25 October 2007.

(3) Wild S, Roglic G, Green A, et al. Global prevalence of diabetes:

estimates for the year 2000 and projections for 2030. Diabetes Care

2004;27(5):1047-53.

(4) Bartnik M, Ryden L, Ferrari R, et al. The prevalence of abnormal

glucose regulation in patients with coronary artery disease across

Europe. The Euro Heart Survey on diabetes and the heart. Eur Heart J

2004;25(21):1880-90.

(5) Ryden L, Standl E, Bartnik M, et al. Guidelines on diabetes, pre-

diabetes, and cardiovascular diseases: executive summar
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