Navigation Links
TAVI is safe alternative to redo cardiac surgery

Use of bioprosthetic heart valves has dramatically increased (from 18% in 1991 to 59% in 2003), mainly in older patients with comorbidities. This is due to the increased risk of bleeding complications associated with lifelong use of anticoagulation for mechanical prostheses.

But structural valve deterioration is one the main complications associated with bioprosthetic heart valves. In large registries including more than 300 000 patients undergoing aortic valve replacement the reoperation rate for patients receiving a bioprosthesis was 3.1% at 11-13 years of follow-up compared with 2.3% reoperation rate for recipients of an aortic mechanical prosthesis.1

Dr Katsanos said: "Reoperation for failed bioprostheses, also called redo cardiac surgery, is associated with increased rates of mortality and morbidity. Less invasive treatments have emerged such as transcatheter valve-in-valve implantation, a type of TAVI operation which is a safe therapeutic option for patients with failed bioprostheses and contraindications for surgery. But until now there has not been a direct comparison of survival between high risk patients treated with either reoperation or a TAVI operation."

The current study assessed the prognosis of patients with failed bioprosthetic aortic and mitral valves and high predicted operative risk who underwent transcatheter valve-in-valve intervention with the Edwards Sapien (23 or 26 mm) valve. They were compared with a historical cohort of patients who underwent elective redo cardiac surgery for failing mitral and aortic prostheses and failing mitral valve annuloplasty.

The TAVI group (age 802 years, 25% men) included 12 patients with failing aortic bioprostheses, 2 with failing mitral bioprostheses and 2 with failed mitral valve annuloplasty. The redo cardiac surgery group (age 701 years, 50% men) had 15 patients with failing aortic bioprostheses and 1 with failing mitral bioprostheses. The reason for valve dysfunction was stenosis in 11 patients, regurgitation in 14 patients and mixed pathology in 7 patients. Patients with endocarditis were excluded. Both groups had similar operative risk, New York Heart Association functional class, and left ventricular ejection fraction.

After a median follow up of 21 (range 7-44) months, 10 (30%) patients died. As shown in the figure, 3-year survival did not differ between patients treated with transcatheter valve-in-valve implantation and those treated with redo cardiac surgery (log-rank p=0.939).

Dr Katsanos said: "We have shown for the first time that the long term survival of high risk patients with failing bioprostheses treated with transcatheter valve-in-valve implantation is comparable to high risk patients treated with redo cardiac surgery."

He concluded: "Transcatheter valve-in-valve implantation is a minimally invasive procedure performed through transfemoral or transapical approach under fluoroscopic guidance and does not require sternotomy and cardiopulmonary bypass. Elderly patients deemed not operable and also high risk patients with failing bioprostheses may have a treatment alternative to redo cardiac surgery."


Contact: Celine Colas
European Society of Cardiology

Related medicine news :

1. Procedure gives patients with A-fib who cant take blood thinners alternative to reduce stroke
2. Study Supports Value of Sigmoidoscopy, an Alternative to Colonoscopy
3. Approval of Safer Alternative to Pradaxa Delayed by FDA
4. Smokers Drop Pricey Cigarettes for Cheaper Alternatives: CDC
5. Alternatives to Medicares fee-for-service payment system examined
6. NHS should replace traditional autopsies with non-invasive alternative
7. Complementary and alternative therapy improved lives of arthritis patients
8. Water Workouts a Great Alternative: Study
9. Controversial Alternative Heart Treatment Shows Hint of Benefit
10. GW researcher receives $4.1 million grant to find alternative treatment for kidney stones
11. Potential new technique for anticancer radiotherapy could provide alternative to brachytherapy
Post Your Comments:
(Date:11/24/2015)... ... November 24, 2015 , ... Cold Shoulder , LLC launched their Pro Vest, the ... and hit their goal of $20,000 in under 10 hours. , The ... new PRO Weight Loss Vest to the market. , The PRO Vest provides consumers with ...
(Date:11/24/2015)... ... November 24, 2015 , ... Chiropractic student Katie Benson ... (CU-KC), in Overland Park, Kansas. Benson, a fifth-trimester student in the university’s College ... III on October 16. , “Katie is very excited and greatly appreciative to ...
(Date:11/24/2015)... ... November 24, 2015 , ... Sir Grout ... service: the TrustDale certification. The award recognizes good companies for excellence in service ... tile and grout, and hard surface restoration company earned this recognition after a ...
(Date:11/24/2015)... MA (PRWEB) , ... November 24, 2015 , ... ... Henry Ford and Detroit Taught Me about Reinvention and Diversity by Nancy M. ... Watching people suffer, with hospitals failing to adequately address the needs of patients and ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... Dr. Kevin ... office to help the community stress less this holiday season. During the Indiana ... stress in people's lives and the team at AlignLife want to help provide the ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , November 25, 2015 - Will ... Medical Education (CME) --> - Will ... Continuing Medical Education (CME) --> ... Continuing Medical Education (CME) ... products and services, will feature latest diagnostic imaging textbooks and decision ...
(Date:11/25/2015)... , November 25, 2015 ... the addition of the  "Global Drug ...  report to their offering.  --> ... addition of the  "Global Drug Device ... to their offering.  --> ...
(Date:11/24/2015)... FRANCISCO , Nov. 24, 2015  Thanks to ... Dignity Health St. Mary,s Medical Center,s Sister Diane Grassilli ... breast imaging capabilities in San Francisco ... an anonymous friend, stepped forward with a gift of ... for Breast Digital Mammography with Tomosynthesis and Whole Breast ...
Breaking Medicine Technology: