Munich, Germany August 28 2012: Transcatheter aortic valve implantation (TAVI) leads to meaningful improvements in health-related quality of life in patients with severe aortic stenosis that are maintained for at least 1 year, according to a study presented at ESC Congress 2012. The results from the German transcatheter aortic valve interventions registry were presented by Professor Till Neumann, MD, from Essen, Germany.
Aortic stenosis is the most common valvular heart disease with increasing incidence especially with regard to the ageing of the population. Today, the prevalence of aortic stenosis is estimated at about 2.5% of 75 year olds and 8.1% of people aged 85 years.
TAVI, introduced in 2002 by Dr Alain Cribier from France and 2005 by Dr John Webb from Canada, has been shown to improve survival compared with standard therapy in patients with severe aortic stenosis who cannot have surgery. In particular, older patients with aortic stenosis cannot always be offered conventional surgical aortic valve replacement at an acceptable risk. As a consequence, about 30% of these patients are presently not operated. Therefore TAVI is currently an alternative treatment option.
The prospective multicentre German transcatheter aortic valve interventions registry includes patients with symptomatic, severe aortic stenosis since January 2009. "The registry was designed to monitor current use and outcome of transcatheter aortic valve interventions, including TAVI, in daily clinical routine, and to evaluate safety, effectiveness and health economic data," said Professor Neumann. "Therefore, the registry gives insight into a real world setting of using the TAVI procedure."
Health-related quality of life was assessed at baseline, at 30 days and 12 months with the EQ-5D questionnaire, a prominent instrument to measure health-related quality of life. The study used quality of life data for a total of 415 patients who survived 12 months after
|Contact: European Society of Cardiology|
European Society of Cardiology