Navigation Links
TAG-1 induces apoptosisrelated gene expression without triggering glioma apoptosis

A recent study reported by Haigang Chang and co-workers from the First Affiliated Hospital of Xinxiang Medical University in China verified the effects of transient axonal glycoprotein-1 (TAG-1) on cell viability and p53, epidermal growth factor receptor (EGFR), and amyloid precursor protein (APP) intracellular C-terminal domain (AICD) expression in U251 glioma cells. Their pilot study showed that the signaling pathways induced by TAG-1, TAG-1/APP/AICD/p53 and TAG-1/APP/AICD/EGFR, did not inhibit glioma development by inhibiting cell proliferation or by inducing apoptosis. Instead, these signaling pathways enhanced proliferation. These findings, which were published in the Neural Regeneration Research (Vol. 9, No. 5, 2014), provide novel insight into the mechanisms of glial tumorigenesis.


Contact: Meng Zhao
Neural Regeneration Research

Page: 1

Related medicine news :

1. Mayo Clinic: Drug induces morphologic, molecular and clinical remissions in myelofibrosis
2. CNIO scientists decipher how the immune system induces liver damage during hepatitis
3. Discovered a mechanism that induces migration of tumor cells in liver cancer
4. Dendritic cell vaccine for relapsed neuroblastoma patient induces complete remission
5. Neurological Wellness Center's Novel Neuro-Inflammation Inhibition Procedure that Induces Rapid Recovery from Alzheimer's, Stroke and Brain Injury is Now Being Taught in a Newly Released Video
6. Tension on gut muscles induces cell invasion in zebrafish intestine, mimicking cancer metastasis
7. Shuganjieyu capsule increases neurotrophic factor expression in a rat model of depression
8. Variable gene expression in zebrafish
9. Occludin and connexin 43 expression in the pathogenesis of traumatic brain edema
10. Gene-expression-based biomarker predicts long-term risk of breast cancer recurrence
11. Researchers report a complete description of gene expression in the human retina
Post Your Comments:
Related Image:
TAG-1 induces apoptosisrelated gene expression without triggering glioma apoptosis
(Date:11/27/2015)... ... November 27, 2015 , ... CBD College is proud ... Education Programs (CAAHEP) awarded accreditation to its Diagnostic Medical Sonography program. CBD College is ... only one of twelve colleges and universities in the state of California make the ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... located in central Michigan, have come together on Thanksgiving Day to share the ... available for viewing on the Serenity Point YouTube channel, patients displayed what they ...
(Date:11/26/2015)... ... ... Jobs in hospital medical laboratories and in the imaging field lead the many ... Medical Group . These fields, as well as travel nursing, ranked at ... through the company’s website, , The leading healthcare staffing agency released ...
(Date:11/26/2015)... ... ... Indosoft Inc., developer and distributor of the world-class Asterisk based contact center software Q-Suite, ... The new Q-Suite 6 platform is based on the latest Java Enterprise standards. By ... piece of software for many key components of the suite. Much of the suite ...
(Date:11/25/2015)... ... 2015 , ... Medical Solutions, one of the nation’s top ... culture with the company’s Cincinnati office being named a finalist among greater Cincinnati’s ... a finalist in Cincinnati Business Courier’s 13th annual Greater Cincinnati Best Places to ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015  The American ... and Gynecologists (ACOG), and the March of Dimes ... Protecting Our Infants Act of 2015 ... number of newborns born exposed to drugs, such ... the bill,s introduction, all three organizations have worked ...
(Date:11/25/2015)... On Tuesday, November 24, 2015, the ... Wright Medical Technology, Inc. for product liability and ... implant device, awarded $11 million in favor of ... and three days of deliberations, the jury found ... designed and unreasonably dangerous, and that Wright Medical ...
(Date:11/25/2015)... AVIV, Israel , November 25, 2015 ... (NASDAQ: KTOV ) (TASE: KTOV), a biopharmaceutical company ... simultaneous treatment of various clinical conditions, today announced the ... 3,158,900 American Depository Shares ( ADSs ), each representing ... purchase up to 3,158,900 ADSs. The ADSs and warrants ...
Breaking Medicine Technology: