Navigation Links
Systems biologist receives $2.5 million Pioneer Award for genome research
Date:9/19/2012

Systems biologist Edward Marcotte has received a $2.5 million grant from the National Institutes of Health to pursue cutting-edge research in the area of genome sequencing technology.

The five-year grant is one of 10 NIH Director's Pioneer Awards given this year. The Pioneer Award, established in 2004, challenges investigators at all career levels to develop innovative approaches that have the potential to produce a high impact on a broad area of biomedical or behavioral research.

Marcotte's project focuses on what he sees as the next step in "next-generation" genome sequencing technology, which can currently sequence more than a billion short DNA molecules per analysis.

"This technology has recently transformed biology," said Marcotte, professor in the Department of Chemistry and Biochemistry. "Unfortunately, no method of similar scale and throughput yet exists to identify and quantify specific proteins in complex mixtures, representing a critical bottleneck in many biochemical, molecular diagnostic and biomarker discovery assays."

Marcotte aims to change that by developing highly parallel strategies for identifying and quantifying individual peptides or proteins in a sample. If successful, the resulting technology would be directly applicable to cancer diagnosis, characterization and protein cancer biomarker discovery.

"It will have broad applications across biology and medicine," said Marcotte.

Marcotte, who is co-director of the Center for Systems and Synthetic Biology in the College of Natural Sciences, has been a pioneer in the development of strategies for sifting through the massive amounts of genetic data that the new sequencing technology is generating.

He uses networks such as those that might illustrate the connections among Facebook users to create maps of the hundreds of thousands of millions of potential relationships among genes and proteins within an organism.

Such an approach has paid off, most recently, in the identification of a potential anti-tumor drug for humans by noting the similarity between genes that grow cell walls in human blood vessels and genes that respond to stress in single-celled yeast.


'/>"/>
Contact: Daniel Oppenheimer
daniel.oppenheimer@utexas.edu
512-745-3353
University of Texas at Austin
Source:Eurekalert

Related medicine news :

1. Study looks at efforts to improve local food systems through policy
2. Fitness 4 Home Online Introduces the Saber Strength Adjustable Weight Systems
3. Cancers with disorganized traffic systems more difficult to treat: U of A research
4. Researchers call for obesity prevention efforts to focus on community-wide systems
5. A systems approach to preventing obesity in early life
6. Program to coordinate regional systems to speed heart attack care
7. Is it time for regional cardiovascular emergency care systems across the US?
8. UC Riverside Biologist named a Leadership Fellow
9. UCI microbiologists find new approach to fighting viral illnesses
10. Texas A&M biologists prove ZOLOFT packs potential to fight fungal meningitis
11. President Obama selects Rutgers cell biologist Nihal Altan-Bonnet to receive prestigious award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... ... health professionals, announced today its affiliation with Tennessee Counseling Association. This ... the network of the Tennessee Counseling Association, adding exclusive benefits and promotional offers. ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A ... 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the ... history as home to some of the world’s leading providers of cereal and other ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Research and ... Market for Companion Diagnostic Tests" report to their offering. ... for Companion Diagnostics The World Market for ... personalized medicine diagnostics. Market analysis in the report includes the ... Market (In Vitro Diagnostic Kits) by Region (N. America, EU, ...
(Date:6/23/2016)... , June 23, 2016  MedSource announced ... as its e-clinical software solution of choice.  This ... best possible value to their clients by offering ... The preferred relationship establishes nowEDC as the EDC ... for MedSource,s full-service clients.  "nowEDC has long been ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
Breaking Medicine Technology: