Navigation Links
Synthetic Platelets Put the Brakes on Blood Loss
Date:12/16/2009

In animals, they cut bleeding time in half, but use in humans is still far off

WEDNESDAY, Dec. 16 (HealthDay News) -- Hoping to improve on nature, researchers have built and tested synthetic versions of the blood-clotting cells called platelets, to be used in trauma or other cases where blood just won't stop flowing.

"We start by making a core, with material that is used in degradable stitches, which dissolve in the body," said Erin B. Lavik, a professor of biomedical engineering at Case Western Reserve University, and lead author of a report published Dec. 16 in Science Translational Medicine. "Then we attach a polymer that is soluble in water and is used in the pharmaceutical industry. Then we attach a molecule that interacts with activated platelets and helps them clot more quickly."

The hope is that the artificial platelets can replace or augment the activity of the currently used clotting medication, known as factor VIIa, Lavik explained.

Factor VIIa is a protein that plays a central role in blood clotting. A genetically engineered version of the protein is now available for medical use. It was introduced for use in people with hemophilia, a genetic condition in which normal clotting does not occur, and it is being increasingly used against uncontrollable hemorrhage.

But factor VIIa must be kept in refrigerated form and has a short shelf life, Lavik said. And it cannot be used for head or spinal cord injuries, for fear of complications.

"The reason we developed this synthetic platelet is that it is stable at all temperatures," Lavik said. "It is a fine powder that can be administered intravenously. The faster you can control bleeding, the better the outcome."

In animal tests, injured rats given injections of the artificial platelets stopped bleeding in half the time of those that went untreated. Rats that got injections 20 seconds after an injury stopped bleeding in 23 per
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Synthetic Red Blood Cells Developed
2. Using synthetic evolution to study the brain: Researchers model key part of neurons
3. Recent Article Reveals Medical Ghostwriting Suppressed Links Between Synthetic Hormones and Breast Cancer
4. Synthetic Protein Thwarts HIV Infection in Lab
5. Thomson Reuters Launches New Developments to Support Synthetic Chemists
6. Sigma-Aldrich Offers Customizable Synthetic Extracellular Matrix for Stem Cell Research
7. Synthetic biology -- opportunities and risks
8. New Study Finds Yet Another Link to Cancer, Synthetic Hormones
9. CPC Files Patent for Synthetic Sealant for the MedClose(TM) Vascular Closure System (VCS)
10. Quark Pharmaceuticals Presents Data on Synthetic siRNAs for Prevention of Ocular and Inner Ear Sensory Cell Damage
11. Organic Left Standing as the Gold Standard for Consumers Looking to Avoid Food Produced With Synthetic Growth Hormones
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... Dallas, TX (PRWEB) December 26, 2014 ... Analysis to 2023” focuses on the current treatment landscape, ... colorectal cancer market. TS-1 is an anti-cancer drug which ... administered orally and is also used for treating gastric ... gimestat and otastat potassium. The drug was first approved ...
(Date:12/25/2014)... December 25, 2014 The short film “Color ... created in honor of a true 9/11 hero, Welles Remy ... festivals including the 24 hours of Nuremberg International Short Film ... , Actress, screenwriter and director Luciana Lagana ... film together with her husband, Gregory Graham - ...
(Date:12/25/2014)... 25, 2014 Recently, LunaDress.co.uk has updated its blog ... related accessories. Now, all of the models at LunaDress.co.uk come with ... groom lifts the wedding veil can turn out to be a ... A wedding veil can always bring surprise to a wedding. On ... how to choose veils for a big day . , ...
(Date:12/25/2014)... HealthDay Reporter WEDNESDAY, Dec. 24, ... a "fountain of youth" drug that can delay the effects ... new study suggests. Seniors received a significant boost to ... genetic signaling pathway linked to aging and immune function, researchers ... experimental medication, a version of the drug rapamycin, improved the ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 Residents ... Retirement Community, recently showed their generous spirit by ... the Catawba County Parenting Network- Grandparents Raising Grandchildren ... children gathered around the largest Christmas tree on ... presents purchased by residents of the Abernethy Village ...
Breaking Medicine News(10 mins):Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 3Health News:Retirement Community Residents Make Impact During Holiday Season 2
... cancer treatment center in Houston stated yesterday that ultrasound is ... cancer in pregnant woman. // ,Dr. Wei ... are hoping to educate young women that the symptomatic breast ... treated while pregnant, and so they should not wait to ...
... launched by the UK Government has been blamed for putting ... process. The Department of Health had proposed to introduce a ... 69 year olds. ,A significant delay has been ... funding and preparation, according to reports of the Cancer Research ...
... neurologist, co-director of the Muscular Dystrophy Association (MDA) ... neurology and pathology at Ohio State University College ... Program and Gene Therapy Center at Columbus Children’s ... Biopharmaceutical Inc (AskBio’s) Biostrophin, which contains a functional ...
... Kartar Singh have been sentenced to two years in jail for ... it if it was female.// This is the first time that ... determination tests and abortions. ,The perpetrators were found out ... Sabani was caught on audio and video telling one of the ...
... the heart and making a correct diagnosis cardiologists are ... students, residents, and other practicing physicians at performing a ... sounds. This was revealed by the findings of two ... ,The study was performed by Dr. Jasminka M. Vukanovic-Criley, ...
... be used for easing the debilitating pain from arthritis. // ... Shulov Institute of Sciences (SIS) in Israel where the research ... snake venom could be on sale within five years. ... most common snake in Israel - and said people suffering ...
Cached Medicine News:Health News:Delay In Life-Saving Bowel Cancer Screening Programme In UK 2Health News:Trial Of DMD Gene Therapy Initiated At Ohio 2
(Date:12/24/2014)... Wis. , Dec. 23, 2014 PuraMed ... marketer of over-the-counter (OTC) medicinal and healthcare products, announced ... of MigraPure® H, a hemp-based, advanced headache relief product, ... dispensaries in Colorado , ... . With the MigraPure H Advanced headache ...
(Date:12/24/2014)... , Dec. 23, 2014  Advanced Medical Isotope ... engaged primarily in the development of brachytherapy devices ... today announced that it has filed a ... Drug Administration ("FDA") for marketing clearance for its ... of the U.S. Food, Drug and Cosmetic Act ...
(Date:12/24/2014)... , December 24, 2014 ... Report on Global Disposable Syringe Industry of ... its online business intelligence library. ... Disposable Syringe Industry is a professional and ... market.  For overview analysis, the report introduces ...
Breaking Medicine Technology:PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 2PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 3Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 2World Disposable Syringe Market 2014 Report: China and Regional Analysis 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 4World Disposable Syringe Market 2014 Report: China and Regional Analysis 5
... WOONSOCKET, R.I., Dec. 11 CVS Caremark (NYSE: ... Senior Vice President and Chief Human Resources Officer, effective January ... announced his retirement. , (Logo: http://www.newscom.com/cgi-bin/prnh/20090226/NE75914LOGO ) ... Caremark, has more than 30 years of human resources experience. ...
... , OXFORD, England, December 11 ... Ii Clinical Results With cat,Allergy T-cell Vaccine , ... Into,Late-Stage Development , Circassia Ltd, a ... completed a GBP15 million ($25 million),fundraising. The investment round, which ...
Cached Medicine Technology:CVS Caremark Names New Chief Human Resources Officer 2Circassia Raises GBP15 Million ($25 Million) in Oversubscribed Investment Round 2
... The SourceLink™ Delivery System offers ... implants. It addresses the challenges associated ... as provides the flexibility of seed ... Seeds packaged per customers desired quantity ...
... EXPRESS Seeding Cartridge System is a single-use, ... seeds and spacers into a Bard BrachyStar ... has a(n): outer radiation safety shield, inner ... spacers, integrally molded fitting that connects the ...
... to bring efficiency and quality to routine ... superior technology of fluorescent flow cytometry with ... sampling or batch processing are easily accommodated ... in high volume laboratories. Fluorescent flow ...
... The Quinton Q-Track II Holter Monitoring System ... that produced the worlds first true 12-lead ... 12-lead presentation of any beat contained in ... analysis. , ,The preprocessing work done by ...
Medicine Products: