Navigation Links
Synthetic Marijuana Use Linked to Kidney Damage
Date:2/12/2013

TUESDAY, Feb. 12 (HealthDay News) -- Synthetic marijuana products, also known as Spice or K2, are potentially very dangerous for the kidneys, new research suggests.

Case studies analyzed by doctors from the University of Alabama at Birmingham found that this designer drug, which mimics the effects of marijuana, has been directly linked to serious kidney damage.

The researchers suggested that doctors should suspect the use of synthetic marijuana when patients, particularly young adults, have unexplained acute kidney damage. They pointed out these man-made drugs can't be detected in routine drug screenings.

"Cases of acute coronary syndrome associated with synthetic marijuana use have been reported, but our publication is the first to associate use with acute kidney injury," study co-author Dr. Gaurav Jain, an assistant professor in the nephrology division, said in a university news release. Abnormally rapid heart rate and seizures have also been reported with synthetic marijuana use, he noted.

The doctors examined four cases of acute kidney damage that were linked to the use of synthetic marijuana. In each case, an otherwise healthy young man went to the emergency room due to nausea, vomiting and abdominal pain after using the drug. All of the men, the researchers noted, lived in the same town in northeastern Alabama, and all of the cases occurred within a nine-week period.

Three of the men had an acute kidney injury that caused their volume of urine to be abnormally low. The fourth man had a drop in effective blood flow to the kidney. Three of the men had a kidney biopsy that showed the death of cells in the kidney that secrete, reabsorb, collect and transport urine. Although this condition can lead to kidney failure, in these cases the men regained their kidney function and did not need dialysis, the study authors noted in the news release.

Because all of the men had used synthetic marijuana, the doctors suggested that how the drug is manufactured may have played a role in its dangerous effects to the kidneys. They pointed out that synthetic marijuana is made with certain additives, which may be toxic to the kidneys.

However, the investigators could not confirm that the drug's preparation causes kidney damage because they couldn't analyze samples of the synthetic marijuana the men took or the men's blood and urine samples, which were no longer available.

"There is very little information regarding the ingredients in synthetic cannabinoids that are sold on the streets, although it is known that additional compounds are added to the preparations," said Jain. He suggested that it is "very likely" that a substance that is toxic to the kidney was added to the drug used by the patients.

The doctors concluded that patients with acute kidney injury should be asked about use of designer drugs, such as synthetic marijuana. "If they don't get to a physician in time, the damage to their kidneys could be permanent, and they could end up on dialysis," cautioned Jain.

The researchers pointed out that synthetic marijuana has become increasingly popular over the past few years because it's relatively cheap and difficult to detect with drug screening tests.

The research was released online in advance of publication in the March print issue of the Clinical Journal of the American Society of Nephrology.

More information

The U.S. National Institute on Drug Abuse has more about synthetic marijuana.

-- Mary Elizabeth Dallas

SOURCE: University of Alabama at Birmingham, news release, Feb. 8, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Biosynthetic grape-derived compound prevents progression of Alzheimers disease in mice
2. Stimulant marketed as natural in sports supplement actually of synthetic origin
3. Synthetic stimulants called bath salts act in the brain like cocaine
4. Scientists explore new class of synthetic vaccines
5. Boston University researchers expand synthetic biologys toolkit
6. Synthetic Skin Heals Itself With a Touch, Study Shows
7. Researchers build synthetic membrane channels out of DNA
8. Probiotic Action Issues a Response to an Article on Medical News Today About Synthetic Skin Research
9. Synthetic Pot Sending Thousands of Young People to ER: Report
10. Strange behavior: New study exposes living cells to synthetic protein
11. Synthetic corkscrew peptide kills antibiotic-resistant Gram-negative bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Synthetic Marijuana Use Linked to Kidney Damage
(Date:2/8/2016)... ... February 08, 2016 , ... ... today that nominations will be accepted February 8, 2016 through May 8, ... Awards include the Information Security Executive® of the Year, which recognizes executives ...
(Date:2/8/2016)... , ... February 08, 2016 , ... ... wide variety of organizations. DocuSyst provides a cloud hosted environment for FileHold ... installations include integration with various 3rd party applications using the FileHold web services ...
(Date:2/8/2016)... Gaithersburg, MD (PRWEB) , ... February 08, 2016 ... ... (AHCC) is excited to share this important news! AHCC and the Home Health ... (AHA) Coding Clinic, CMS' designee for official ICD coding guidance and clarifications, to ...
(Date:2/8/2016)... ... ... Guruji Mahendra Kumar Trivedi is offering 3 days of accelerated personal growth ... on February 10th. During this time, people can achieve better health, greater wealth, ... from over 40 different countries as an “ordinary man with an extraordinary gift.” ...
(Date:2/7/2016)... Clarkston, Metamora, Michigan (PRWEB) , ... February 07, ... ... correct pelvic organ prolapse with the latest techniques and the most minimally invasive ... for pelvic organ prolapse, particularly after menopause. Other risk factors include surgery to ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... EAST NORRITON, Pa. , Feb. 8, 2016 ... acquisition of November Research Group (NRG),s pharmacovigilance ... of pharmacovigilance system-related consulting services and an Oracle ... regulatory compliance services to Life Sciences companies. ... acquisition strengthens and expands HighPoint,s life sciences capabilities ...
(Date:2/8/2016)... Pa. , Feb. 8, 2016  As part of ... has announced today the appointment of Lori Chmura ... than 20 years in the industry, Chmura,s extensive experience in ... the advancement of Dune Medical Devices. ... will be responsible for leading all sales, marketing and operational ...
(Date:2/8/2016)... Velano Vascular, a medical technology company transforming ... their practitioners, announced today that the company has raised ... the proceeds from this financing, an extension of a ... to support the development and commercialization of the company,s ... Philadelphia , and a number ...
Breaking Medicine Technology: