Navigation Links
Swiss Institute of Bioinformatics announces major breakthrough
Date:9/24/2008

Speaking at the 10th anniversary conference of the Swiss Institute of Bioinformatics in Berne, Switzerland, its director Professor Ron Appel described his institute as a "Swiss success story". He said that he was proud that as pioneers at the heart of science one of the SIB's 25 working groups was today able to announce the completion of the annotation of human proteins.

Professor Amos Bairoch, head of the SIB's Swiss-Prot group said: "If human DNA is the script of life, proteins are its actors, its living embodiment."

He added that the human genome-sequencing project produced a dictionary. This new encyclopaedia takes one major step further by looking at life as it is really organised in our body at the molecular level. The results will speed up the scientific work which aims to improve our quality of life. Particularly when it comes to understanding what life is, and how we can combat genetic-based diseases.

While proteins are the essence of life, when they become defective they can cause much suffering and often early death. Man's knowledge of proteins such as insulin and haemoglobins is crucial to combating diseases such as cancer, Alzheimer's, cystic fibrosis and haemophilia.

Professor Bairoch said, "The general public would understand some of the entries in our protein encyclopaedia. Insulin, for instance, is a small protein that controls glucose levels in our blood. The performance-booster EPO is the protein used illegally by some cyclists. In the human body it takes many forms. But we detect its use in sport because competitors use a manufactured form which is not natural."

The new protein encyclopaedia, which will evolve further as our knowledge is refined, now informs a major part of the work of thousands of health researchers around the word. The data covers 20,325 human proteins. The information could ultimately be used for developing exact treatments for individual patients based on an understanding of their specific protein set.

The breakthrough can be seen as one of the 21st century's major life science outcomes. It can help improve our chances of defeating a variety of diseases, by enabling researchers to model the interaction between individual patients, diseases and drugs.

Progress on the Human Protein Initiative (HPI) project has been rapid. Ten years ago, we had good data on less than 1000 proteins. Two years ago, we had good entries for 15,000, now the collection is complete. But one of the remaining challenges, though, is still to complete the same encyclopaedia of proteins for other animals.

Professor Bairoch said, "More than 45,000 scientific papers were read. We examined databases that were out there to get a picture of the knowledge which existed. We had to go out and find the material."

This new protein encyclopaedia is published online and available for free to users. In printed form, it would correspond to 57 volumes of about 1,000 pages each.

SIB director praise donors, scientists and working groups

The Swiss Institute of Bioinformatics director Professor Ron Appel closed the press conference praising the collaboration between five universities and two institutes of technology across the length and breadth of Switzerland.

He said: "Their collective success shows what can be achieved when experts pool their knowledge and vision.

"The SIB is a pioneering institute. More successes can be expected in future. These will add to what is already an impressive track record in all the fields of bio-informatics technology research we work in."

He also emphasised that without the support of the Swiss government and international partners, none of this would be possible, "so we owe a big thanks to them", he added.

In addition, Professor Bairoch thanked the Swiss government, international funding agencies and all the scientists who contributed to their recent breakthrough. He said, "ours is just one of the 25 SIB groups working at the frontiers of scientific knowledge for the benefit of mankind".


'/>"/>

Contact: Janice Blondeau
janice.blondeau@isb-sib.ch
41-216-924-054
Swiss Institute of Bioinoformatics
Source:Eurekalert

Related medicine news :

1. Swiss study suggests surgery may offer best chance of long-term prostate cancer survival
2. First Pharmaceutical Company Comes to Hoboken, NJ: Swiss-Based Octapharma to Move U.S. Headquarters to SJP Properties Waterfront Corporate Center II
3. Swiss Systems Biology Initiative announces Flagship Projects
4. The Risk Management and Patient Safety Institute Announces Annual Health Care Risk Conference Dates
5. Mayo Clinic Multidisciplinary Simulation Center Receives Distinction as an ACS-Accredited Education Institute
6. LifeNet Health Establishes The Skin & Wound Allograft Institute
7. Statement from Employment Policies Institute on Senator Hillary Clintons Health Care Plan
8. CAS Medical Systems, Inc. Awarded $2.8 Million Grant by National Institutes of Health
9. Portico Systems to Share Provider Network Management Best Practices at Institute for International Research
10. The Integrated Benefits Institute Offers Largest Benchmarking Database in U.S. Spanning Disability and Workers Compensation Programs
11. The Cooper Institutes FITNESSGRAM Selected as Statewide Physical Fitness Assessment Tool
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... Bruton Memorial Library on June 21 due to a possible lice infestation, as reported by ... lice: the parasite’s ability to live away from a human host, and to infest common ... the event that lice have simply gotten out of control. , As lice are a ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for ... $12 an hour by 2020 and then adjusting it yearly to increase at the same ... wage, assure the wage floor does not erode again, and make future increases more predictable. ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... is actively feeding the Frederick area economy by obtaining investment capital for emerging ... the past 2½ years that have already resulted in more than a million ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  MedSource announced today ... its e-clinical software solution of choice.  This latest ... possible value to their clients by offering a ... preferred relationship establishes nowEDC as the EDC platform ... MedSource,s full-service clients.  "nowEDC has long been a ...
(Date:6/23/2016)... 2016 Roche (SIX: RO, ROG; OTCQX: RHHBY) ... Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated testing ... With this clearance, Roche is the first IVD company ... for sepsis risk assessment and management. PCT ... PCT levels in blood can aid clinicians in assessing ...
(Date:6/23/2016)... , , , WHEN: , , ... , , , LOCATION: , , , Online, with free registration ... PANELISTS:  , , , Frost & Sullivan,s Global Vice President of ... Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... witnessing an exceptional era. Several new demand spaces, such as innovative ...
Breaking Medicine Technology: