Navigation Links
Swine Flu Shots Safe for People With Weak Immune Systems: Experts
Date:9/18/2009

Another study outlines risks of catching H1N1 from various routes

FRIDAY, Sept. 18 (HealthDay News) -- The H1N1 swine flu vaccines approved this week by the U.S. Food and Drug Administration can be safely used by people with compromised immune systems, according to new recommendations from the American Academy of Allergy, Asthma & Immunology.

These would include people whose immune responses are weakened by medical treatments (such as for cancer or organ transplant) and those infected with HIV, the experts said.

Influenza vaccines can be made from live -- but modified and weakened -- virus, or they can be made from the harmless byproducts of the virus (so-called "killed" virus vaccines). According to the experts at the American Academy of Allergy, Asthma & Immunology (AAAAI), all of the injected H1N1 vaccines so far approved by the FDA are of the "killed" variety.

"There's never any harm with giving killed influenza vaccine" to immuno-compromised individuals, said Dr. Kenneth Bromberg, director of the Vaccine Research Center at The Brooklyn Hospital Center in New York City.

There is one vaccine out there that those with weakened immune systems should avoid: the nasal spray form of the seasonal ("regular") flu vaccine, FluMist.

FluMist is derived from live (but very weakened) virus, so it could pose a problem for people with poor immune systems. The recommendation to avoid FluMist extends to people living in close proximity to an immune-compromised person, such as family members, because they could pass on the live virus to that individual, the AAAAI said.

No such threat exists for average Americans with robust immune responses, the experts said.

One question for some people with compromised immune systems is whether the flu shot will actually help them, given their poor immune defenses.

People with so-called "primary" immune deficiency -- rare immune deficiencies inherited at birth -- can take the H1N1 vaccine, the academy said. "Although the antibody response may be poor or low [in these individuals], the cell-mediated response may be a helpful immune response to [fight] the virus," AAAAI President-elect Dr. Mark Ballow said in a news release issued Thursday.

But, depending on their level of immune cell function, certain HIV-infected individuals may not be able to mount enough of an immune response to make flu vaccination worthwhile, the experts said.

"The issue is whether the compromised immune response might result in insufficient protection, not whether the inactivated H1N1 or seasonal influenza vaccine is excessively harmful," said Dr. Paul Greenberger, president of AAAAI.

"The CDC (U.S. Centers for Disease Control and Prevention) notes that most HIV patients can receive the immunization, and from earlier studies with seasonal flu shots, [it appears] there may be a reduced response if the number of CD4+ lymphocytes is less than 100/mm3," Greenberger said. "Better responses occurred if patients had CD4+ lymphocyte counts of at least 400."

He added that "studies haven't been published yet of H1N1 vaccination in HIV patients."

In other swine flu news, a study published in the September issue of the journal Risk Analysis seeks to quantify the risk from various routes of transmission of the swine flu virus. Researchers from the University of California, Berkeley, and the University of Illinois used sophisticated modeling and pored over the available data on four key means of person-to-person H1N1 transmission.

They speculate that hand contact with a contaminated surface brings a 31 percent risk of actual infection; inhaling tiny particles laden with virus in a room brings a 17 percent likelihood of infection; close contact where coughs spray viral-laden droplets onto the eyes, nostrils or lips brings a 52 percent chance of infection. Inhaling relatively large particles carrying virus when three feet or nearer to an infected person carries only a 0.52 percent risk for infection, the research team said.

According to the researchers, the study strengthens current recommendations to cover the mouth when coughing and to disinfect commonly touched surfaces.

More information

There's more on H1N1 flu at the U.S. Centers for Disease Control and Prevention.



SOURCE: Paul Greenberger, M.D., president, American Academy of Allergy, Asthma & Immunology; Kenneth Bromberg, M.D., director, Vaccine Research Center, The Brooklyn Hospital Center, New York City; Sept. 17, 2009, news release, American Academy of Allergy, Asthma & Immunology; Sept. 16, 2009, news release, Society for Risk Analysis


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Swine Flu Loves a Crowd
2. FDA Approves 4 Swine Flu Vaccines
3. People With Swine Flu May Be Contagious Longer Than Thought
4. Small Businesses Urged to Prepare for Swine Flu
5. Swine Flu Trials Continue to Point to 1-Dose Vaccine
6. One Dose of Swine Flu Vaccine Offers Protection: Studies
7. H1N1 Swine Flu Preparedness Uncertainty Results in Higher Business Disruption Risk
8. Insite Security Hosts Webinar on Swine Flu Preparedness
9. Swine Flu Burrows Into Lungs: Study
10. Swine Flu Shots May Come Too Late to Stem Fall Outbreak: Study
11. With All Eyes On Swine Flu, Thousands of Parents Ask President Obama How Much Longer Until Autism Gets Similar Attention
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Swine Flu Shots Safe for People With Weak Immune Systems: Experts
(Date:6/27/2016)... ... , ... TopConsumerReviews.com recently awarded their highest five-star rating to Best Buy Eyeglasses, ... the United States and Canada wear eyeglasses. Once considered to be a purely functional ... a fashion statement. Even celebrities use glasses as a way of creating an iconic ...
(Date:6/26/2016)... Creek, Michigan (PRWEB) , ... June 26, 2016 , ... ... joined as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in ... in honor of the city’s history as home to some of the world’s leading ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... ... fertility once they have been diagnosed with endometriosis. These women need a treatment ... also require a comprehensive approach that can help for preservation of fertility and ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Key Pharma News Issue 52" report to their offering. ... need in influenza treatment creates a favourable commercial environment for ... and growing patient base that will serve to drive considerable ... flu vaccine would serve to cap sales considerably, but development ...
(Date:6/23/2016)... Ill. and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment ... Astellas Farma Brasil as the company,s second affiliate in Latin America . ... ... General Manager of Astellas Farma Colombia ... ...
(Date:6/23/2016)... June 23, 2016 Research and ... Procedure Volumes: Global Analysis (United States, China, Japan, Brazil, ... report to their offering. ... for healthcare business planners, provides surgical procedure volume data ... trends with an in-depth analysis of growth drivers and ...
Breaking Medicine Technology: