Navigation Links
Sustained virological response linked with improved survival for patients with chronic HCV infection
Date:12/25/2012

Among patients with chronic hepatitis C virus infection and advanced hepatic fibrosis (development of excess fibrous connective tissue), sustained virological response (SVR) to interferon-based treatment was associated with a lower risk of all-cause mortality compared with patients without SVR, according to a study in the December 26 issue of JAMA.

"Chronic hepatitis C virus (HCV) infection is a major cause of cirrhosis, hepatocellular carcinoma (HCC), and end-stage liver disease. The incidence of HCV-related cirrhosis and its complications is expected to increase in upcoming years. Davis et al estimated that currently 25 percent of the approximately 3.5 million U.S. patients with chronic HCV infection have cirrhosis and that the proportion of patients with cirrhosis is likely to increase up to 45 percent by 2030," according to background information in the article.

"Sustained virological response is defined as absence of viremia [the presence of a virus in the blood] 24 weeks after cessation of all antiviral medication. Although SVR has long-term durability, data on the relationship with improved survival to support its use as a surrogate end point of antiviral therapy is scarce. Demonstrating direct clinical benefits would better justify the use of intensive and costly antiviral therapy " the authors write.

Adriaan J. van der Meer, M.D., of Erasmus MC University Medical Center, Rotterdam, the Netherlands and colleagues conducted a study to examine whether achievement of SVR vs. without SVR is associated with a prolonged overall survival in patients with chronic HCV infection and advanced hepatic fibrosis. The study, conducted at five tertiary care hospitals in Europe and Canada, included 530 patients with chronic HCV infection who started an interferon-based treatment regimen between 1990 and 2003, following histological proof of advanced hepatic fibrosis or cirrhosis. Complete follow-up ranged between January 2010 and Octo
'/>"/>

Contact: Harry L. A. Janssen
h.janssen@erasmusmc.nl
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Renal denervation achieves significant and sustained blood pressure reduction
2. Cancer cells co-opt immune response to escape destruction
3. NIH scientists reflect on gains in emerging infectious disease awareness, research and response
4. Investigational agent targets gene signaling pathways to improve response for patients with CLL
5. Probiotic Action Issues a Response to an Article on Medical News Today About Synthetic Skin Research
6. Study Tracks Brain Gene Response to Territorial Aggression
7. Researchers develop non-invasive technique for predicting patients response to chemotherapy
8. Genetically-engineered preclinical models predict pharmacodynamic response
9. Feeding microbials to chickens leads to mysterious immune response
10. Adding bavituximab to second-line chemotherapy doubles response rate
11. Trudeau researchers identify unforeseen regulation of the anti-bacterial immune response
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... Dallas, Texas (PRWEB) April 22, 2015 ... Pipeline Review, H1 2015” provides comparative analysis ... The report strengthens R&D pipelines by identifying ... and best-in-class products. Complete report with TOC ... , The report also reviews key players ...
(Date:4/21/2015)... TX (PRWEB) April 21, 2015 The ... announced today it is opening its first freestanding emergency ... in Chandler, Arizona and will be licensed under Dignity ... the Dignity Health and Adeptus Health joint venture. , ... Regional and Mercy Gilbert Medical Centers said the new ...
(Date:4/21/2015)... & New York, NY (PRWEB) April 21, 2015 ... global provider of advanced delivery technologies and development ... today announced the launch of ADVASEPT™ Lock, a ... and efficient delivery of injectable medications. Easily opened, ... a safe, convenient and functional container closure with ...
(Date:4/21/2015)... Carinsurancehints.com has released a new blog post presenting ... auto insurance prices . , Commuting on ... should review their insurance options before deciding what plan ... forms. Some of the popular policies provide liability, collision ... rates and find the best prices in their area ...
(Date:4/21/2015)... April 21, 2015 This year, in ... Skin Types, Inc.® (FIRST) will publish a unique awareness ... will run throughout the month of May and carry ... to Someone." The positioning was chosen to encourage ... skin disorder and to help support our mission of ...
Breaking Medicine News(10 mins):Health News:Pulmonary Embolism Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 2Health News:Pulmonary Embolism Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 3Health News:Pulmonary Embolism Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 4Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 2Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 3Health News:Catalent Announces the Expansion of its Advanced, Aseptic, Glass-Free Injectable Platform with New ADVASEPT™ Lock Delivery Technology 2Health News:Heavily Circulated Roads Can increase Auto Insurance Costs 2Health News:May is Ichthyosis Awareness Month. Use Your Voice. 2
... /Xinhua-PRNewswire/ -- WuXi PharmaTech,(Cayman) Inc. (NYSE: ... device research and development outsourcing company with ... announced it has reached an agreement,with Johnson ... of,Janssen Pharmaceutica, N.V. (J&JPRD) to expand its ...
... ST. LOUIS, Oct. 15 Young Innovations, Inc.,(Nasdaq: ... third quarter,earnings results with a live and on-demand web ... Central Time. A live audio broadcast of the,call will ... the live audio broadcast will also be available through ...
... Options,(CCO), a leader in the development of innovative online, ... agreement with,the American Association for the Study of Liver ... unique Conference Coverage of AASLD,s,Liver Meeting(R) 2008, which will ... 4, 2008., "Clinical Care Options has a proven ...
... DUBLIN, Ohio, Oct. 15 Foresight Corporation ... Debra Strickland has joined the,company,s Development division ... http://www.newscom.com/cgi-bin/prnh/20081015/CLW134 ), In this role, ... customers to,propose and design new technical solutions, ...
... 15 Darwin,Professional Underwriters, Inc. (the "Company") (NYSE: ... meeting of the Company,s stockholders held on October ... Plan of Merger,(the "Merger Agreement"), dated as of ... Company Holdings, Ltd ("Allied World") and Allied,World Merger ...
... a sentry guarding the castle walls, a molecular messenger inside ... that could allow the invasion of an insidious enemy: Cancer. ... in its tracks, preventing an error that could lead to ... suggests that to be able to prevent abnormal cell proliferation, ...
Cached Medicine News:Health News:WuXi PharmaTech Expands Collaboration for Fully Integrated Services 2Health News:Young Innovations, Inc. Provides Third Quarter Conference Call Details 2Health News:American Association for the Study of Liver Diseases Enters Into Agreement With Clinical Care Options as Its Authorized Online Conference Coverage Provider for the Liver Meeting(R) 2008 2Health News:Debra Strickland joins Foresight Corporation in time for HIPAA 5010 Mandate 2Health News:Darwin Stockholders Adopt Merger Agreement with Allied World 2Health News:Darwin Stockholders Adopt Merger Agreement with Allied World 3Health News:Stem-cell sentry sounds the alarm to maintain balance between cancer and aging, U-M researchers find 2
(Date:4/21/2015)... 21. April 2015  CorTechs Labs, der ... Analyse des Hirnvolumens freut sich, eine Partnerschaft ... bekannt geben zu können. Die Unternehmen werden ... Hirnvolumens zusammenarbeiten, der die Identifizierung, Messung und ... mit multipler Sklerose als Ziel hat. ...
(Date:4/21/2015)... , April 21, 2015 Gary A. ... National Minority Quality Forum (NMQF), today will present ... the Pharmaceutical Research and Manufacturers of America ... clinical trials. On behalf of PhRMA, and in conjunction ... campaign to build awareness, start conversations, and increase diversity ...
(Date:4/21/2015)... LOS ANGELES , April 21, 2015 ... symptomatic uterine fibroids known as the Acessa™ procedure is ... Southern California women aged 25-55 who ... Lee , MD, FACOG, the inventor and world,s leading ... to hysterectomy and myomectomy, has helped establish two new ...
Breaking Medicine Technology:CorTechs Labs kündigt Partnerschaft für die Bereitstellung umfassender Lösungen zur Quantifizierung des Verlustes von Hirnvolumen bei multipler Sklerose an 2National Minority Quality Forum to Award PhRMA President John Castellani for Leadership in Increasing Clinical Trial Diversity 2National Minority Quality Forum to Award PhRMA President John Castellani for Leadership in Increasing Clinical Trial Diversity 3New Minimally Invasive Treatment for Uterine Fibroids Offers Life-Changing Relief, Without a Hysterectomy, to 1 Million Southern California Women 2New Minimally Invasive Treatment for Uterine Fibroids Offers Life-Changing Relief, Without a Hysterectomy, to 1 Million Southern California Women 3New Minimally Invasive Treatment for Uterine Fibroids Offers Life-Changing Relief, Without a Hysterectomy, to 1 Million Southern California Women 4
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: