Navigation Links
Sustained virological response linked with improved survival for patients with chronic HCV infection
Date:12/25/2012

Among patients with chronic hepatitis C virus infection and advanced hepatic fibrosis (development of excess fibrous connective tissue), sustained virological response (SVR) to interferon-based treatment was associated with a lower risk of all-cause mortality compared with patients without SVR, according to a study in the December 26 issue of JAMA.

"Chronic hepatitis C virus (HCV) infection is a major cause of cirrhosis, hepatocellular carcinoma (HCC), and end-stage liver disease. The incidence of HCV-related cirrhosis and its complications is expected to increase in upcoming years. Davis et al estimated that currently 25 percent of the approximately 3.5 million U.S. patients with chronic HCV infection have cirrhosis and that the proportion of patients with cirrhosis is likely to increase up to 45 percent by 2030," according to background information in the article.

"Sustained virological response is defined as absence of viremia [the presence of a virus in the blood] 24 weeks after cessation of all antiviral medication. Although SVR has long-term durability, data on the relationship with improved survival to support its use as a surrogate end point of antiviral therapy is scarce. Demonstrating direct clinical benefits would better justify the use of intensive and costly antiviral therapy " the authors write.

Adriaan J. van der Meer, M.D., of Erasmus MC University Medical Center, Rotterdam, the Netherlands and colleagues conducted a study to examine whether achievement of SVR vs. without SVR is associated with a prolonged overall survival in patients with chronic HCV infection and advanced hepatic fibrosis. The study, conducted at five tertiary care hospitals in Europe and Canada, included 530 patients with chronic HCV infection who started an interferon-based treatment regimen between 1990 and 2003, following histological proof of advanced hepatic fibrosis or cirrhosis. Complete follow-up ranged between January 2010 and Octo
'/>"/>

Contact: Harry L. A. Janssen
h.janssen@erasmusmc.nl
JAMA and Archives Journals
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Renal denervation achieves significant and sustained blood pressure reduction
2. Cancer cells co-opt immune response to escape destruction
3. NIH scientists reflect on gains in emerging infectious disease awareness, research and response
4. Investigational agent targets gene signaling pathways to improve response for patients with CLL
5. Probiotic Action Issues a Response to an Article on Medical News Today About Synthetic Skin Research
6. Study Tracks Brain Gene Response to Territorial Aggression
7. Researchers develop non-invasive technique for predicting patients response to chemotherapy
8. Genetically-engineered preclinical models predict pharmacodynamic response
9. Feeding microbials to chickens leads to mysterious immune response
10. Adding bavituximab to second-line chemotherapy doubles response rate
11. Trudeau researchers identify unforeseen regulation of the anti-bacterial immune response
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... The current residents of Back2Basics - Long Term ... staff all came together Saturday, May 18th to celebrate the ... Cuisine, the residents got up to thank Roy Duprez, CEO ... road to recovery, and giving them a second chance at ... 2010 after realizing the need for a long-term facility. ...
(Date:5/25/2013)... CA (PRWEB) May 25, 2013 ... news of a judge's overturning of a jury's award ... in the first trial* in the country over allegations ... according to court files. , The judge in the ... evidence to show his cancer was caused by the ...
(Date:5/25/2013)... AdvantaClean of Pikes Peak recently opened and ... healthy home and business in Colorado Springs and surrounding ... inspections, mold testing, mold removal , air ... , With over 120 offices nationwide, AdvantaClean is a ... full suite of services for commercial, institutional, and governmental ...
(Date:5/24/2013)... A recent study by research group Harris ... upcoming bathing suit season. Almost 138 million people are fearful ... due to weight issues and a quarter admit they feel ... Labs recommends that those anxious about their size consider the ... of an overall effort to improve diet and exercise habits ...
(Date:5/24/2013)... Part guidebook, part memoir, Peter Amato, ... and true approach to meditation for the recovery community. ... 11th Step, the book outlines a comprehensive method for ... 11th step in any 12-step recovery programs such as ... an ever-growing global health problem affecting the physical and ...
Breaking Medicine News(10 mins):Health News:Back2Basics Drug and Alcohol Rehabilitation Center Celebrates Their 3rd Anniversary 2Health News:Alleged Actos Bladder Cancer Lawsuits Update: $6.5 Million Verdict Overturned as Resource4thePeople Attorneys Continue to Accept Cases 2Health News:Alleged Actos Bladder Cancer Lawsuits Update: $6.5 Million Verdict Overturned as Resource4thePeople Attorneys Continue to Accept Cases 3Health News:Alleged Actos Bladder Cancer Lawsuits Update: $6.5 Million Verdict Overturned as Resource4thePeople Attorneys Continue to Accept Cases 4Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 2Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 3Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 4Health News:PhenObestin 37.5 Can Help Make Bathing Suit Season Less Stressful 2Health News:PhenObestin 37.5 Can Help Make Bathing Suit Season Less Stressful 3Health News:Guidebook for Recovery Published by Meditation Master Peter Amato 2Health News:Guidebook for Recovery Published by Meditation Master Peter Amato 3
... ANGELES, Oct. 3 Pink tags will be ... the supermarket chain partners,with vendors and suppliers to ... Throughout the month, pink tags can be found ... identify participating products,customers can purchase to support breast ...
... Interested in Stopping their Periods, But Unsure,About Medical Implications, ... of,women in a national survey say that they are ... aren,t sure if it,s safe. Yet when,physicians are polled, ... menstruation is, in fact, medically safe and,acceptable. The survey ...
... than the two thirds of the women in a ... their menstrual periods but many of them arent sure ... percent say that continuous oral contraceptive therapy to suppress ... survey results were presented by Kurt Barnhart MD, MSCE ...
... QUINCY, Mass., Oct. 3 The Stop & Shop Supermarket,Company, ... $75,000 to,Susan G. Komen for the Cure with the Pink ... Month," said Stop & Shop/Giant,Consumer Advisor Andrea Astrachan, "and by ... Giant, customers can support the fight against,breast cancer and help ...
... Inverness Medical,Innovations (Amex: IMA ) today announced ... both core laboratory and point of care,diagnostic testing products ... Inverness will pay an earn out up to a ... had,revenues of approximately $29.5m in 2006 and has been ...
... Workers in PA, MI, IL, FL, OH, MD, WI, WA Join Forces in, ... Equity ... Buyout, WASHINGTON, Oct. 3 ... union today,is launching a multi-state grassroots campaign calling on global buyout,giant the Carlyle ...
Cached Medicine News:Health News:Ralphs 'Pink Tag' Campaign to Raise $170,000 for Breast Cancer Awareness in October 2Health News:Safe to Stop the Flow?: Differing Attitudes Found Between Women and Doctors Concerning Menstrual Suppression 2Health News:Safe to Stop the Flow?: Differing Attitudes Found Between Women and Doctors Concerning Menstrual Suppression 3Health News:Differing attitudes found between women and doctors concerning menstrual suppression 2Health News:Stop & Shop and Giant Food Join General Mills in Pink for the Cure 2Health News:Inverness Medical Innovations Acquires Bio-Stat Healthcare Group 2Health News:SEIU Launches Multi-State Grassroots Campaign Calling on the Carlyle Group to Put Care Above Profits in Buyout of Nation's Largest Nursing Home Chain 2
(Date:5/24/2013)... May 24, 2013  An international roster of experts ... 18, in Santa Monica, Calif. , ... therapies for MPM, a rare form of cancer that ... pleura, the lining of the chest. Hosted ... Institute, the 3rd Annual International Symposium on Lung-Sparing Therapies ...
(Date:5/24/2013)... May 24, 2013 China Biologic Products, Inc. ... fully integrated plasma-based biopharmaceutical company in China ... learned from a public announcement issued by Shanghai RAAS ... listed on Shenzhen Stock Exchange, that on May 21, ... ("Ms. Chan"), one of the shareholders of the Company, ...
(Date:5/24/2013)... 24, 2013 In accordance with Rule 17.1 and ... of the United States Exchange Act, Echo Pharma Acquisition Limited ... Elan Corporation (NYSE: ELN). Background On ... an offer for the entire of the issued and to ... "Original Offer").  On 20 May 2013, Royalty ...
Breaking Medicine Technology:International Mesothelioma Experts Present Promising New Research Findings at the 3rd Annual International Symposium on Lung-Sparing Therapies for Malignant Pleural Mesothelioma 2International Mesothelioma Experts Present Promising New Research Findings at the 3rd Annual International Symposium on Lung-Sparing Therapies for Malignant Pleural Mesothelioma 3China Biologic Comments on the Proposed Shanghai RAAS Transaction 2China Biologic Comments on the Proposed Shanghai RAAS Transaction 3China Biologic Comments on the Proposed Shanghai RAAS Transaction 4Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 2Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 3Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 4Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 5Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 6Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 7Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 8Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 9
... Masimo (Nasdaq: MASI ... showcasing Masimo noninvasive patient monitoring technologies were presented last ... Annual Meeting in San Diego, California.  The largest ... Meeting provides an important platform for previewing the latest ...
... Wash., Oct. 27 The International Foundation for ... announce the forthcoming release of the mSCAN (mobile ... (Sonography Clinical Assessment Notebook), was developed by IFSER ... for clinical assessment tools in sonography. Based on ...
Cached Medicine Technology:Over 20 New Clinical Studies Presented on Masimo Noninvasive Patient Monitoring Technologies at the American Society of Anesthesiologists Annual Meeting 2Over 20 New Clinical Studies Presented on Masimo Noninvasive Patient Monitoring Technologies at the American Society of Anesthesiologists Annual Meeting 3Over 20 New Clinical Studies Presented on Masimo Noninvasive Patient Monitoring Technologies at the American Society of Anesthesiologists Annual Meeting 4Over 20 New Clinical Studies Presented on Masimo Noninvasive Patient Monitoring Technologies at the American Society of Anesthesiologists Annual Meeting 5Over 20 New Clinical Studies Presented on Masimo Noninvasive Patient Monitoring Technologies at the American Society of Anesthesiologists Annual Meeting 6Over 20 New Clinical Studies Presented on Masimo Noninvasive Patient Monitoring Technologies at the American Society of Anesthesiologists Annual Meeting 7Over 20 New Clinical Studies Presented on Masimo Noninvasive Patient Monitoring Technologies at the American Society of Anesthesiologists Annual Meeting 8Over 20 New Clinical Studies Presented on Masimo Noninvasive Patient Monitoring Technologies at the American Society of Anesthesiologists Annual Meeting 9IFSER: Introducing the mSCAN 2
... This antimicrobial skin cleanser will not leave ... with frequent washings. With persistent Antimicrobial action, ... of microorganisms, including gram-negative and gram-positive bacteria, ... as a 15 second hand wash. The ...
... Prep Pads prepares the skin for improved ... dry, it leaves a thin film on ... surface and a barrier for natural body ... a dressing or tape. Skin Protectant is ...
... Povidone Iodine Prep Pads ... surface pathogens including bacteria, ... yeast. Povidone Iodine is ... wounds or mucus membranes. ...
Aplicare's Prep Pads offer convenience, low cost, ease of use. The medium size is appropriate for most applications. Each package is terminally sterilized, ensuring the safest possible product for th...
Medicine Products: