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Susan G. Komen for the Cure(R) and Triple Negative Breast Cancer Foundation Unite to Fight Aggressive Form of Breast Cancer
Date:1/12/2009

TNBCF's initial $500,000 contribution marks the first time a nonprofit partner has co-funded one of Komen's groundbreaking Promise Grants. Worth $7.5 million over five years, Promise Grants are designed to bring clinical researchers and basic scientists together to deliver new treatments for patients as quickly as possible.

To date, doctors know that most breast cancers are characterized by the presence of three receptors (proteins found inside or on the surface of breast cells): estrogen, progesterone and HER2. These receptors are not "expressed" in women with triple negative breast cancer - hence the name. Since most treatments available today are aimed at those receptors, TNBC is difficult to treat, and the tumors are often more aggressive. TNBC represents only 15 percent of all breast cancer cases but accounts for as many as 25 percent of all breast cancer deaths.

To accelerate our understanding of this rare form of the disease, a "think tank" of 31 researchers from leading cancer institutions worldwide was convened by Komen and TNBCF at the symposium in December.

Led by Dr. Eric Winer, Komen chief scientific advisor and TNBCF advisory board member, as well as Drs. Lisa Carey and George Sledge, also of the TNBCF advisory board, the symposium focused on topics ranging from how well TNBC responds to traditional chemotherapy to the unique ways TNBC spreads through the body.

"This unprecedented partnership with TNBCF is critical in the drive to better understand this difficult-to-treat type of breast cancer," Moddelmog said. "The more resources we devote to triple negative breast cancer, the sooner we'll find a cure."

About Susan G. Komen for the Cure(R)

Nancy G. Brinker promised her dying sister, Susan G. Komen, she would do everything in her power to end breast cancer forever. In 1982, that promise became Susan G. Komen for the Cure and launched the globa
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SOURCE Susan G. Komen for the Cure
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