Navigation Links
Survivors of childhood liver transplant at risk of becoming 'skinny fat'
Date:6/12/2014

New research reports that survivors of childhood liver transplant remain nutritionally compromised over the long-term. Findings published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, indicate that the recipients' return to normal weight post-transplant was due to an increase in fat mass as body cell mass remained low, indicating a slim body composition with little lean muscle mass or "skinny fat."

Children with end-stage liver disease may be malnourished due to inadequate food consumption, abnormal absorption of nutrients, or excessive increase in metabolism (hypermetabolic state). Previous studies suggest that malnutrition may reduce body fat, protein stores, body cell mass, and cause deficiencies in fat soluble vitamins, iron, zinc, and selenium before transplant; and increase mortality after liver transplantation. The "gold standard" for assessing nutritional status is by measuring body cell mass using the total body potassium measurement.

For the present study Dr. Looi Ee and colleagues from The University of Queensland in Brisbane, Australia recruited 32 children aged less than 18 years, who were scheduled for liver transplant at the Royal Children's Hospital. Researchers measured total body mass prior to liver transplant and at follow-up on average seven years post-transplant. Patient age at transplant, growth impairment, biliary atresia diagnosis and steroid use were also examined.

Twenty of the participants were male, 62% had biliary atresia, and the average age at transplant was two years. Results showed the patients' body cell mass for height (BCM/Heightp) was reduced prior to liver transplant, but further reduced after transplant despite height and weight returning to normal. Analyses indicate that older age at transplant predicted reduced post-transplant BCM/Heightp) . Researchers did not find that gender, age at transplant, steroid use, and underlying diagnosis predicted changes in BCM/Heightp).

"Our study found reduced body cell mass in those who underwent childhood liver transplant up to 15 years post-transplant, despite a return to normal height and weight following surgery," said Dr. Ee. "Likely weight recovery was due to increased fat masswhat would be called "skinny fat"since body cell mass did not improve."


'/>"/>
Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert  

Related medicine news :

1. Childhood cancer survivors hospitalized frequently years after cancer treatment
2. Guidelines address long-term needs of prostate cancer survivors
3. New report estimates nearly 19 million cancer survivors in the US by 2024
4. St. Jude researcher honored by ASCO for work in childhood cancer survivorship
5. MRI catches breast cancer early in at-risk survivors of childhood Hodgkin lymphoma
6. Study calls for revisiting cardiac screening guidelines for survivors of childhood cancer
7. Vanderbilt study finds physical signs of depression common among ICU survivors
8. Adjuvant chemotherapy increases markers of molecular aging in the blood of BC survivors
9. Twenty-five percent of breast cancer survivors report financial decline due to treatment
10. Multidisciplinary teams helped marathon bombing survivors rebuild their lives
11. Imprint of chemotherapy linked to inflammation in breast cancer survivors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Survivors of childhood liver transplant at risk of becoming 'skinny fat'
(Date:5/27/2016)... , ... May 27, 2016 , ... Two director-level employees ... YWCA Tribute to Women and Industry (TWIN) 2016 honorees. The award recognizes businesswomen ... For this year, Geri Boone, Director of the MLTSS (Managed Long-Term Services and Supports) ...
(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... ... readers, this installment is bolstered by inspiring human-interest stories, courtesy of awareness-driven celebrities ... within the industry, from leading advocates, associations and industry leaders such as Bioness. ...
(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... ... in scholarships to students studying complementary medicine. Allison Outerbridge is this year’s ... her award on May 18 at the university’s Student Leadership Awards ceremony. , ...
(Date:5/26/2016)... California (PRWEB) , ... May 26, 2016 , ... ... associated with discovery of thousands of defective respirators, according to court documents and ... the case of William and Becky Tyler v. American Optical Corporation, Case No. ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... The ... Project offering a new model of care for living and healing, celebrated its ... values: Meaningful Life in a Real Home provided by Empowered Staff. , “This is ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... , May 25, 2016 Digital ... issuance to it by the US Patent and ... company,s technology includes proprietary processes for electronic opt-­in ... health and wellness programs, HIPAA compliance and otherwise. ... "Our technology allows ...
(Date:5/24/2016)... Niederländische Chirurgen haben eine ... Ärzten erlaubt, ihre Expertise weltweit zu teilen und ... Streaming mit einer Instant-Messaging-Funktion und der Möglichkeit, in ... Europa, Afrika, Asien und den USA ... registriert. Information und Weiterbildung   ...
(Date:5/24/2016)... May 24, 2016  Diana Russell suffers from a ... from the inside out.  This disease has put her ... her children and grandchildren to leave her home.  Because ... family cannot haul the wheelchair.  So if there is ... and Diana is left to wait for the bus. ...
Breaking Medicine Technology: