Navigation Links
Surviving Mesothelioma Examines the Future of the Mesothelioma Drug Whose Clinical Trial Was Stopped Early This Week
Date:9/30/2015

Although a clinical trial of defactinib (VS-6063) for mesothelioma was shut down this week because of “futility”, the jury is still out on whether the drug may work better in combination than by itself. Surviving Mesothelioma has more on the company’s plans for defactinib. Click here to read the full article.

Verastem, the makers of the FAK-inhibitor defactinib, said in a statement that the trial of the drug as a single agent for mesothelioma was not having enough impact to justify its continuation.

“With the aggressiveness of this disease, the use of single agent VS-6063 as a maintenance treatment following chemotherapy where all patients had residual disease was not sufficient,” explains Verastem Chief Medical Officer Lou Vaickus, MD.

But another mesothelioma trial that pairs defactinib with an FAK-inhibitor called VS-5584 is still recruiting patients and the company says there is evidence that the two agents may work “synergistically” to fight mesothelioma.

“Although this particular drug does not appear to prevent mesothelioma relapse by itself, it should be encouraging for patients and families to know that other similar drugs and drug combinations are still in the pipeline,” says Surviving Mesothelioma Managing Editor Alex Strauss.

For more on this week’s announcement and a better understanding of how FAK-inhibitors like defactinib are thought to work against mesothelioma, see Scrubbed Trial May Not Be the End for Mesothelioma Drug, now available on the Surviving Mesothelioma website.

“Verastem Stops Enrollment Due to Futility in the COMMAND Study of VS-6063 for the Treatment of Malignant Pleural Mesothelioma”, Company Statement, Verastem website, September 28, 2015, http://phx.corporate-ir.net/phoenix.zhtml?c=250749&p=irol-newsArticle&ID=2090793

Read the full story at http://www.prweb.com/releases/2015/10/prweb12991891.htm.


'/>"/>
Source: PRWeb
Copyright©2015 Vocus, Inc.
All rights reserved

Related medicine news :

1. Patients and Advocates Raise Awareness for Deadly Preventable Cancer, According to Surviving Mesothelioma
2. Surviving Mesothelioma Shines a Spotlight on World’s Longest-Living Mesothelioma Survivor in Advance of Mesothelioma Awareness Day
3. Study Finds Combination Therapy Produces Long-Term Mesothelioma Survival in Small Group of Patients, According to Surviving Mesothelioma
4. New Study Finds Trimodal Treatment Approach for Mesothelioma Prolongs Survival, According to Surviving Mesothelioma
5. Doctors Highlight “Learning Curve” for Mesothelioma Surgery in New Report, According to Surviving Mesothelioma
6. Swiss Team Proposes Prognostic Score for Mesothelioma Surgical Candidates, According to Surviving Mesothelioma
7. New Study Appears to Validate the Safety of Mesothelioma Surgery for Older Patients, According to Surviving Mesothelioma
8. Researchers Say Mesothelioma Not the Only Cancer Linked with Asbestos Exposure, According to Surviving Mesothelioma
9. Top Mesothelioma Researchers Highlight Targeted Therapies in New Report, According to Surviving Mesothelioma
10. Surviving Mesothelioma Puts New Orphan Drug into Perspective in New Article
11. Scientists Say Enzymes May Influence Chemotherapy Response in Mesothelioma, According to Surviving Mesothelioma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/3/2020)... ... September 03, 2020 , ... MemoryCare.com, a ... the Best Memory Care Facilities in Louisville, KY. The guide identifies 17 memory ... , According to the Alzheimer’s Association , 5.6 million people age 65 ...
(Date:9/1/2020)... , ... September 01, 2020 , ... ... new practice in Glendale. While the office will be the first to ... augmentation, tummy tucks, buttock augmentation (Brazilian butt lift), as well as rhinoplasty, facial ...
(Date:9/1/2020)... Calif. (PRWEB) , ... September 01, 2020 , ... As ... “safe side”, the Cohn Health Institute has taken this time to expand ... celebration of its 30th Anniversary, the Cohn Health Institute will be relaunching its brand ...
(Date:8/31/2020)... ... 2020 , ... The Lymphoma Research Foundation (LRF) ... and serving the lymphoma community through a comprehensive series of education programs, outreach ... Awareness Month (BCAM) and its international Light it Red for Lymphoma ...
(Date:8/31/2020)... ... , ... Want to get moving, break up your routine, and make a ... to launch its fourth annual STEPtember campaign in the United States to raise funds ... they are at this moment — encouraging people to move in the ways that ...
Breaking Medicine News(10 mins):
(Date:9/3/2020)... ... September 03, 2020 , ... In response to the ... schools and classrooms across the United States, IntraLogic Solutions , a leading ... TEMPE is a non-contact, wall-mounted scanning thermometer that rapidly checks body temperatures. When ...
(Date:9/2/2020)... and ROCKWALL, Texas (PRWEB) , ... ... ... Powerful Preventative in the Fight Against Covid-19 , Advanced Penetration Technology, LLC, ... innovative healthcare solutions for patients utilizing non-prescription, Over The Counter (OTC) products, ...
(Date:9/1/2020)... ... September 01, 2020 , ... Agilent, a global leader in ... and Technology Virtual Symposium 2020 (ASTVS 2020) on September 10-11, opening at ... Live webinars and Networking sessions, with a vast array of on-demand presentations to ...
Breaking Medicine Technology: