Navigation Links
Survival rates appear lower for scalp and neck melanoma than for other sites
Date:4/21/2008

Individuals with melanoma on their scalp or neck appear less likely to survive for five or 10 years than those with melanoma at other sites, according to a report in the April issue of Archives of Dermatology, one of the JAMA/Archives journals.

Melanoma rates continue to increase while rates for most other cancers decline, according to background information in the article. The significance of tumor location in determining cancer prognosis has been debated for decades, the authors note. Understanding the role of anatomic site in melanoma survival is important for public health messages on skin awareness and sun protection, they write. Moreover, because the role of screening in melanoma is considered important for early detection, it is useful to clarify those characteristics with prognostic significance.

Anne M. Lachiewicz, M.P.H., of the University of North Carolina School of Medicine, Chapel Hill, and colleagues analyzed data from U.S. cancer registries for 51,704 individuals first diagnosed with melanoma between 1992 and 2003. Of those, 43 percent had melanomas on their arms or legs, 34 percent on the trunk, 12 percent on the face or ears, 6 percent on the scalp or neck and 4 percent at an unspecified site.

Survival rates were lower among those with scalp and neck melanoma than among those with melanoma at other sites both five years (83.1 percent vs. 92.1 percent) and 10 years (76.2 percent vs. 88.7 percent) after diagnosis. Fourteen percent of those with scalp/neck melanoma and 44 percent of those with melanomas at unknown sites died compared with only 6 percent of those with extremity [arm or leg] melanoma, 8 percent with trunk melanomas and 6 percent with face/ear melanomas, the authors write. After controlling for other factorsincluding age, tumor thickness and sexpatients with melanoma on their neck or scalp died at 1.84 times the rate of those with melanoma on their arms or legs.

The reason for worse survival among patients with scalp/neck melanomas is unclear, the authors write. The blood supply and lymphatic drainage systems serving these areas are rich and complex, which may make it easier for melanoma cells to penetrate and circulate. In addition, such patients are more likely to have cancer that spreads into their brain than those with melanoma on their arms, legs or trunk. Finally, the skin lesions may be hidden by hair and therefore diagnosed later than those at other sites.

The recognition that scalp/neck location is associated with poorer melanoma survival has implications for screening and public health recommendations, the authors conclude. We suggest that all full-skin examinations and future screening studies include a careful inspection of the scalp/neck.


'/>"/>

Contact: Leslie H. Lang
919-843-9687
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Gestational Age Not Sole Predictor of Preemie Survival
2. Interleukin-12 indicates survival prospects for melanoma patients
3. Combining liver cancer treatments doubles survival rates, UVA researchers find
4. Mayo Clinic identifies treatment target for liver cancer recurrence and survival
5. High-intensity chemotherapy does not improve survival in small cell lung cancer
6. State Report Ranks LIJ as New Yorks Best Hospital for Angioplasty Survival
7. Home Defibrillators Fail to Boost Survival Rates
8. Drug Therapy Boosting Heart-Attack Survival Rates
9. Molecular science could further improve leukemia survival, say St. Jude researchers
10. Frying Tumors Can Boost Lung Cancer Survival
11. Combo Treatment Ups Survival When Cancer Spreads to Abdominal Lining
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2017)... ... July 25, 2017 , ... Therachat , a smart ... and providing demos of its smart journaling platform at the 125th American Psychological ... D.C. from August 3-6, 2017. , The APA Annual Convention is one of ...
(Date:7/25/2017)... WI (PRWEB) , ... July 25, 2017 , ... ... Aloria Health, as medical director. Dr. Negrette has more than a decade of ... She has worked closely with individuals fighting addictions, eating disorders, psychotic and manic ...
(Date:7/25/2017)... TX (PRWEB) , ... July 25, 2017 , ... SignatureCare ... emergencies in the Austin, TX area 24 Hours a day. , The ... Austin, TX. , “We’ve been open four months now and things are running ...
(Date:7/24/2017)... ... 2017 , ... Cheerag D. Upadhyaya , M.D., M.Sc., FAANS has been ... (SLMBNI), part of Saint Luke’s Health System . Dr. Upadhyaya has served in ... M.Sc., FAANS joins Stanley P. Fisher, M.D., who has served as medical ...
(Date:7/24/2017)... ... July 24, 2017 , ... BayMark Health Services ... Health Services Administration’s (SAMHSA) State Targeted Response to the Opioid Crisis program. ... will facilitate the development of a hub and spoke model for opioid treatment ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... , July 13, 2017 RK Logistics Group, ... of Pharmacy certification for its Fremont, CA ... solutions in the Tri-Valley and San Jose ... City of Fremont , with its Fremont Innovation ... to provide such a powerful resource to the hundreds of ...
(Date:7/12/2017)... INDIANAPOLIS , July 12, 2017  Eli Lilly and ... settlement agreement with generic companies to resolve pending patent litigation ... Virginia regarding the Cialis ® ... expire on April 26, 2020. As part of the agreement, ... on September 27, 2018. "The unit dose patent ...
(Date:7/11/2017)... 2017  The global market for liquid biopsy diagnostic ... million in 2016.  Although in early stages, the global ... particular as a result of the gradual shift towards ... introduction of a significant number of new liquid biopsy ... tumor biomarkers to guide treatment decisions. ...
Breaking Medicine Technology: