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Survival matching should be used to allocate donated kidneys to transplant recipients
Date:3/17/2011

ient.
  • Allocating the 20% highest quality kidneys to the 20% of candidates with the longest expected post-transplant survival.
  • Allocating the remaining 80% of kidneys such that candidates who are within 15 years (older or younger) of the donor's age have highest priority.

    Because of the current system and the aging of the candidate pool, post-transplant life span following kidney transplantation in the United States has declined on average by 18 months since 1995, Leichtman says.

    The authors say that computer simulations based on the current donor pool suggest that more than 35,000 years of post-transplant survival are lost each year under the current system. Additionally, more than 10,000 years of incremental post-transplant survival -- extra years of life that would not have been achieved without the benefit of transplant also are lost each year.

    "We are wasting hundreds of thousands of potential years of life," Leichtman says. "The proposal for survival matching as described in the concept document has the potential to reclaim many of these lost years of life, and therefore warrants serious consideration."

    The authors also support using the proposed Kidney Donor Profile Index. The new index provides a more granular and accurate survival estimate for organs.

    "We suspect that utilization rates of shorter-lived kidneys will increase with accurate information about their survival potential and reduced opportunity for potentially short-lived candidates to be allocated kidneys with long estimated post-transplant survival," the authors wrote.

    About 80,000 people are listed nationwide for a kidney transplant. Demand continues to increase, some of it driven by an unnecessarily high rate of repeat transplantations because kidneys and recipients weren't well matched, says Leichtman.

    Kidney transplants are the most common transplants done at the University of Michigan Transplant Center and nationwide. But more than half of t
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  • Contact: Mary F. Masson
    mfmasson@umich.edu
    734-389-5381
    University of Michigan Health System
    Source:Eurekalert

    Page: 1 2 3

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