Navigation Links
Survival in metastatic breast cancer directly linked to circulating tumor cells
Date:5/6/2010

Brussels, 6 May 2010 -- A new study of metastatic breast cancer shows that the number of circulating tumor cells patients have in their blood directly correlates with the length of their survival. Reported at the IMPAKT Breast Cancer Conference in Brussels, Belgium, the results have the potential to improve the delivery of personalized therapy to these patients.

Circulating tumor cells --cancer cells found in a patient's bloodstream-- are detected in 50% to 80% of patients with metastatic breast cancer. Since 2004, doctors have known that patients with 5 or more of these cells in 7.5 ml of blood survive on average for less time than those with fewer than 5 cells.

Dr Antonio Giordano from MD Anderson Cancer Center in Houston, USA, and colleagues set out to refine this prognostic test using a sophisticated computer model known as an artificial neural network.

"We chose to use an artificial neural network model to analyze 516 consecutive metastatic breast cancer patients at the University of Texas MD Anderson Cancer Center because, unlike more typical statistical methods, it can estimate the complex interactions between different factors over time," said Dr Giordano. "Our model, designed at the University of Naples Federico II, simply represents a dynamic time-related analysis of survival, taking into account all prognostic factor correlations."

Using the artificial neural network, the researchers studied the relationship between increasing numbers of circulating tumor cells and survival for different subgroups of breast cancer.

"We found that there was a linear relationship between the number of circulating tumor cells and the risk of death in patients with metastatic breast cancer. Most importantly, the risk of death after 1 year for patients with 40 circulating tumor cells in 7.5 ml of blood was about twice that for patients with none."

"These results show that the simple cutoff number of 5 circulating tum
'/>"/>

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. One Sigmoidoscopy Boosts Colon Cancer Survival Odds
2. Youngest Preemies Survival Rate Unchanged
3. Researchers Boost Post-Heart Attack Survival in Mice
4. Beta-blockers help reduce metastasis and improve survival in breast cancer patients
5. Survival in metastatic breast cancer patients is improving: targeted therapies have contributed
6. Pregnancy for breast cancer survivors: Meta-analysis reveals it is safe and could improve survival
7. Accepting Help Improves Survival Among Diabetics
8. New therapies increase survival rates in post-transplant liver cancer patients
9. Chemo May Boost Survival After Lung Cancer Surgery
10. Recurrence of breast cancer after more than 10 years is an important indicator of survival
11. Mammograms May Not Boost Survival, Danish Study Suggests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... CA (PRWEB) July 24, 2014 The ... new online training course designed to help users generate ... public generating a buzz of excitement throughout the internet ... caught the attention of HonestyFirstReviews.com’s Tiffany Hendricks prompting a ... anyone who’s been involved in internet marketing will tell ...
(Date:7/24/2014)... (PRWEB) July 24, 2014 Ticket Down ... Roma Tickets in Denver at the Sports Authority Field on ... (or World Football Challenge) has brought some of the best club ... With the World Cup still being raved about weeks after its ... chance to see some of the biggest stars in the world ...
(Date:7/24/2014)... The report, “Content Delivery Networks (CDN) Market”, ... sub-segments with an in-depth analysis and forecasting of ... for this market with insights on trends, opportunities, ... and 36 figures spread through 157 pages and ... at http://www.marketsandmarkets.com/Market-Reports/content-delivery-networks-cdn-market-657.html . , Early buyers ...
(Date:7/24/2014)... York, New York (PRWEB) July 24, 2014 ... GranuFlo lawsuits ( http://www.injurybeacon.com/granuflo-dialysis/lawsuit/ ) in the ... a qualified protective order for plaintiff medical information ... Accountability Act. According to the July 16th Order, ... granted attorneys for Fresenius Medical Care the ...
(Date:7/24/2014)... In a July 9th article in the Money ... Lotus Blossom Consulting LLC , was quoted in a Family ... Cut the High Cost of Infertility . Her advice began ... maximize your chance of success from the first attempt.” The ... “I am always happy to talk with the media ...
Breaking Medicine News(10 mins):Health News:Traffic And Leads Training Academy - Review Examining Jeff Johnson’s New IM Course Released 2Health News:Manchester United vs. AS Roma Tickets Denver Sports Authority Field at Mile High: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match 2Health News:Manchester United vs. AS Roma Tickets Denver Sports Authority Field at Mile High: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 2Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 4Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuits Move Forward in Federal Court, With Issuance of Protective Order for HIPAA Information, Bernstein Liebhard LLP Reports 4Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 2Health News:Mindy Berkson, Infertility Expert and Founder, Lotus Blossom Consulting LLC: Leading the Pathway to Parenthood 3
... ... A valuing parent/child relationship is required, not just discipline. , ... (PRWEB) May 20, 2010 -- There’s a dangerous parenting trend ... discipline (to spank or not to spank, etc.) with little to no attention on a ...
... The Swanson ... with unique benefits. , ... ND (Vocus) May 19, 2010 -- Friendly bacteria may seem like an oxymoron—we have been ... everyone needs bacteria to survive. Bacteria are responsible for the digestion of food, for ...
... Hands-On Care ... Manual Physical Therapy have been producing pain relief in otherwise unresolved chronic pain cases. ... (PRWEB) May 20, 2010 -- ... Myofascial Pain examine and treat chronic pain sufferers from all over the world. “I ...
... population of middle-aged cystic fibrosis patients contains significantly more ... lived for decades without a diagnosis or specialized care, ... Health. The comprehensive analysis of this over-40 cohort, published ... Respiratory and Critical Care , may help guide future ...
... are still being prescribed for extended periods to British Columbian ... warnings against long-term use, according to a University of British ... Policy , the study by researchers at UBC,s Centre for ... its kind to examine the use of benzodiazepines such as ...
... , WEDNESDAY, May 19 (HealthDay News) -- Two common ... equally effective, a new study reveals, but each option ... slings, the techniques are often used to address stress ... as coughing, sneezing or laughing. , Urinary incontinence affects ...
Cached Medicine News:Health News:Celebrate Mental Health Month with Your Child; Make Sure a Valuing Relationship is in Place 2Health News:FemFlora Reformulated with New Complex of Probiotic Bacteria 2Health News:New Laser Technology Combined with Manual Physical Therapy Offer Pain Relief to Chronic Pain Sufferers 2Health News:Older patients offer insight into the future of cystic fibrosis 2Health News:Older patients offer insight into the future of cystic fibrosis 3Health News:Long-term use of anti-anxiety drugs continues in B.C. despite known health risks: UBC study 2Health News:Female Incontinence Surgeries Look Equally Effective 2
(Date:7/24/2014)... -- IGI Laboratories, Inc. (NYSE MKT: IG), a New Jersey based ... results for the second quarter ended June 30, 2014. ... of $6.5 million in the second quarter of 2014, an ... , Total revenues of $13.3 million for the six months ... same period in 2013 , Total revenues generated from ...
(Date:7/24/2014)... RALEIGH-DURHAM, N.C. , July 24, 2014 /PRNewswire/ ... company has signed an Agreement with Kineticos, a ... sciences consulting company. Kineticos will support LSI Medience ... in sepsis management, to demonstrate utility in clinical ... has shown potential utility in diagnosis of sepsis, ...
(Date:7/24/2014)...  The American Association for Homecare (AAHomecare) yesterday ... help address audit issues in the HME industry ... the information technology lead in shaping its HME ... billing and business management solutions for nearly 3,000 ... support this important initiative on behalf of all ...
Breaking Medicine Technology:IGI Laboratories Announces Second Quarter 2014 Results 2IGI Laboratories Announces Second Quarter 2014 Results 3IGI Laboratories Announces Second Quarter 2014 Results 4IGI Laboratories Announces Second Quarter 2014 Results 5IGI Laboratories Announces Second Quarter 2014 Results 6IGI Laboratories Announces Second Quarter 2014 Results 7LSI Medience Corporation and Kineticos Sign Agreement Related to the Presepsin Biomarker in Sepsis Management and Treatment 2Brightree Joins AAHomecare as Corporate Partner and IT Lead on HME Audit Key 2
... China , July 22 /PRNewswire-Asia-FirstCall/ -- ... developing and producing botanical extracts and other raw ... receipt of its,European order for approximately 80 metric ... pharmaceutical company. This order is valued at,approximately ...
... A total joint replacement registry based on carefully designed and ... according to a paper published online in Clinical Orthopaedics and Related ... , , ... Permanente,s Total Joint Replacement Registry -- the nation,s largest such registry -- ...
Cached Medicine Technology:Huifeng Bio-Pharmaceutical Technology Announces a New Spain Order 2Huifeng Bio-Pharmaceutical Technology Announces a New Spain Order 3Kaiser Permanente Demonstrates Success of Large-Scale Total Joint Replacement Registry 2Kaiser Permanente Demonstrates Success of Large-Scale Total Joint Replacement Registry 3Kaiser Permanente Demonstrates Success of Large-Scale Total Joint Replacement Registry 4
... fume containment system is ... equipment. Even large benchtop ... the Hyperclean 2. The ... unit comes complete with one ...
Reusable shielded cable...
... OIA test features a dual-detection technology to ... for children under age 5 with a ... in just over 15 minutes. This combination ... to decrease costs for unnecessary ancillary testing, ...
... OIA A/B test combines performance equivalence to 14-day ... A or B with a simple, easy-to-use test ... test has all the same procedural steps as ... enable you decrease costs for unnecessary ancillary testing, ...
Medicine Products: