Survival differences by race most apparent in advanced stages of bre...(n with breast cancer (21861 African Amer...),Health

Date:8/13/2007

n with breast cancer (21,861 African American and 234,313 white) diagnosed from 1988-2003 showed that African American women were more likely than white women to be diagnosed with tumors greater than 2.0-cm and to have at least one lymph node with disease. However, racial differences in lymph node involvement were apparent only in tumors smaller than 3.0 cm.

After adjusting for tumor size and lymph node status as well as other known factors, such as age, African American women were still more likely to die from their disease. The mortality rate among African American women was calculated to be up to 56 percent higher than whites.

This study confirms statistically significant differences within stage between black and white women in tumor size and nodal involvement. However, the authors conclude, these differences are not clinically important with respect to survival over and above the standard AJCC stage categories.

The study also found that as stage of disease at diagnosis increases, so too does the gap in mortality between African American and white women. The authors postulate that the factors that prevent black women from receiving the same quality of care as white women may be exacerbated by the more complex treatment regimens used for more advanced breast cancer.

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Contact: Amy Molnar amolnar@wiley.com John Wiley & Sons, Inc. Source:Eurekalert

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