Navigation Links
Survival benefit with high-intensity end-of-life approaches

PITTSBURGH, Feb. 11 Patients admitted to hospitals with higher-intensity end-of-life care live longer than those admitted to hospitals with low-intensity approaches, according to a University of Pittsburgh study available online and published in the February issue of the journal Medical Care. Higher-intensity care refers to greater use of life-sustaining measures such as ICU admission, intubation or mechanical ventilation, kidney dialysis and feeding tubes.

The study, led by Amber E. Barnato, M.D., M.P.H., associate professor of medicine, clinical and translational science and health policy, University of Pittsburgh, examined admission records of more than one million patients 65 and older in Pennsylvania hospitals between 2001 and 2005.

The researchers found a survival benefit in hospitals with more intensive treatment styles, but this benefit lessened with time. After 30 days, patients treated at high-intensity hospitals had a 7 percent risk of dying compared to 9 percent at low-intensity hospitals. By six months post-admission, the risk of dying increased to 18 percent compared to 19.5 percent respectively. Risk of dying was the same for higher-intensity hospitals as average-intensity hospitals six months after admission.

Unlike previous studies that assessed records of people who died having received life-sustaining measures, Dr. Barnato and colleagues looked at all seniors admitted to hospitals to determine the impact of intensity style on survival.

"Looking solely at people who received life support and died will not give you a true indication of how these measures impact survival," said Dr. Barnato. "That's akin to being a Monday morning quarterback. Instead, we looked at a hospital's approach to people who were sick enough to die."

The study did not address questions about the cost effectiveness of greater end-of-life treatment intensity or the quality of life experienced by the patients who lived longer because they went to a more intensive hospital.

"Ongoing controversies about the utility and cost effectiveness of life-sustaining treatment for individual patients will not be solved by this study. However, our findings support the strategy of hospitals 'moving toward the middle,' when it comes to life-sustaining interventions," said Dr. Barnato.

Co-authors include Chung-Chou Chang, Ph.D., Max H. Farrell, S.B., Judith R. Lave, Ph.D., Mark S. Roberts, M.D., and Derek Angus, M.D., all with the University of Pittsburgh.

The study was funded by the National Institutes of Health's National Institute on Aging.

Contact: Clare Collins
University of Pittsburgh Schools of the Health Sciences

Related medicine news :

1. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
2. Paxil Blocks Tamoxifen, Lowers Survival Odds Against Breast Cancer
3. DBLG Announces Release 1.0 of the HITECH Act Survival Guide: an Open Source Law Initiative
4. Intensive Insulin Therapy Wont Boost Septic Shock Survival
5. Cancer survival disparities for most minority populations increase as cancers become more treatable
6. Physical Activity May Prolong Survival After Colon Cancer
7. Mayo Clinic Proceedings: Researchers find evidence of survival gains in bone marrow disease
8. Mayo Clinic researchers say breast cancer survival improves Herceptin used with chemotherapy
9. Vitamin D Linked to Survival in Lymphoma Patients
10. Sonic Hedgehog variations linked to recurrence, survival and response to therapy of bladder cancer
11. Pixantrone Produces 250% Relative Improvement in 1 Year Progression Free Survival for Patients With Relapsed/Refractory, Aggressive Non-Hodgkins Lymphoma Across All Measured Risk Factors - Updated Follow-Up Data
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... For the first time, Vitalalert ... Organizations, One Beat ” campaign. The partnership between the two groups began in 2014 ... MAP International’s cause. , MAP International was founded in 1954 and is an international ...
(Date:11/25/2015)... ... ... On November 25, 2015, officials of Narconon Arrowhead , the drug rehabilitation ... new cutting edge recovery program that has been 50 years in the making. ... with the purpose to free addicts from the symptoms and negative behaviors of addiction. ...
(Date:11/25/2015)... ... ... Smiles by Stevens is pleased to announce the addition of Botox® for ... aware of the benefits of Botox® in the treatment of moderate facial wrinkling, few ... and pain as a result of Jaw Tension, TMJ (temporo-mandibular joint) disorder, and Bruxism ...
(Date:11/25/2015)... ... November 25, 2015 , ... In an ongoing Clinical Study conducted by an ... IL, UV Angel is evaluating the efficacy of its product and its disinfection protocol. ... 30 beds) from May 2014 through October 2015 at a 360-bed, acute-care, academic medical ...
(Date:11/25/2015)... Spring, Md (PRWEB) , ... November 25, 2015 ... ... Pulmonary Hypertension Association (PHA) announces the nation’s Periwinkle Pioneers, individuals and groups responsible ... history of this disease. The Periwinkle Pioneers, nominated by the public, will receive ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 2015 Kitov Pharma ceuticals ... a biopharmaceutical company focused on the development of therapeutic ... today announced the closing of its previously announced underwritten ... ), each representing 20 ordinary shares of the Company, ... ADSs and warrants were issued in a fixed combination ...
(Date:11/25/2015)...  Today AVACEN Medical announced the issue of United States patent No. ... ". This patent shields the company,s AVACEN 100 dry heat therapy medical device and specific methods ... Photo - ... ... ...
(Date:11/25/2015)... , Nov. 25, 2015 USP 800 ... drug preparations (e.g. pharmacists, pharmacy technicians, nurses, physicians, ... technicians). The chapter also covers all entities which ... pharmacies, hospitals, other healthcare institutions, patient treatment clinics, ... --> --> What is ...
Breaking Medicine Technology: