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Surveyed Experts Indicate That the Combination of Sutent and Taxol Has Advantages Over the Combination of Avastin and Taxol in the Treatment of Metastatic Triple-Negative Breast Cancer
Date:4/22/2009

Sutent/Taxol Will Earn Decision Resources' Clinical Gold Standard Status for the Indication by 2012, According to a New Report from Decision Resources

WALTHAM, Mass., April 22 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed oncologists identify a therapy's effect on overall survival as the attribute that most influences their prescribing decisions in metastatic triple-negative breast cancer. Clinical data and the opinions of interviewed thought leaders indicate that Pfizer's Sutent, in combination with Bristol-Myers Squibb's Taxol, has advantages in this attribute over sales-leading Roche/Chugai's Avastin and Taxol.

The new report entitled Metastatic Triple-Negative Breast Cancer: Physicians Want More-Efficacious Therapies for This Niche CaB Population finds that a therapy that improves progression-free survival for patients would earn a 65 percent patient share in metastatic triple-negative breast cancer in the United States and a 30 percent patient share in Europe, according to surveyed U.S. and European oncologists.

In 2008, Decision Resources' proprietary clinical gold standard for metastatic triple-negative breast cancer was the combination of Avastin and Taxol. Based on available data and expert opinion, the combination of Sutent and Taxol will earn gold-standard status for metastatic triple-negative breast cancer in 2012, following Sutent's approval for the indication in 2010 in the U.S. and Europe.

"Physicians anticipate that the combination of Sutent and Taxol will be more effective than currently available therapies in improving progression-free survival," said Decision Resources Analyst Niamh Murphy, Ph.D. "Interviewed thought leaders indicate that Sutent has shown compelling preclinical data and they are encouraged by clinical trial results of Sutent monotherapy."


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