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Surprise in Lab Helps ID Drug to Fight ALS
Date:1/24/2008

rials must be conducted to determine if apocynin is effective in people.

The discovery of the interaction between SOD1 and Rac1 may prove to have widespread importance.

"It is exciting not only from the standpoint of ALS, but also because of its implications for understanding basic cell biology. Rac1 is implicated in many cellular processes including cellular migration, proliferation and differentiation, and is an important component of inflammatory disease processes," team leader John Engelhardt, head of anatomy and cell biology at UI's Roy J. and Lucille A. Carver College of Medicine, said in a prepared statement.

More information

The Muscular Dystrophy Association has more about ALS.



-- Robert Preidt



SOURCE: University of Iowa, news release, Jan. 24, 2008


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