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Surgical technique halts cell loss, Parkinson's researchers find
Date:9/2/2008

While the control group's loss of dopamine neurons increased to 75 percent after two weeks, the rats implanted with active stimulators experienced no further loss of cells during that time.

Subsequent tissue analysis revealed that in rats implanted with active stimulators the trophic factor BDNF had tripled in the striatum, a part of the brain that houses dopamine terminals and "receives" the dopamine neurotransmitters that are produced in the substantia nigra.


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Contact: Cindy Starr
cstarr@mayfieldclinic.com
513-569-5321
University of Cincinnati
Source:Eurekalert

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