Navigation Links
Surgical excision unnecessary in some patients with benign papillomas

Imaging surveillance is an acceptable alternative to surgical excision in patients with benign papilloma, diagnosed at breast core biopsy without cell abnormalities, a new study shows.

The study, conducted at the Breast Health Center of California Pacific Medical Center in San Francisco, included 119 papillomas diagnosed at core biopsy without abnormal cells. Imaging follow-up of a minimum of two years without surgical excision was performed on 66 lesions; no cancer was found in this group, said Jessica Leung, MD, FACR, lead author of the study. Surgical excision was done on the remaining 53 lesions, with 50 of those being benign. Ductal carcinoma in situ was diagnosed in the remaining three lesions, she said.

The "histological upgrade rate" (the core biopsy indicated the lesion was benign, but the surgical excision found cancer) was 2.5%, said Dr. Leung. This upgrade rate "approximates the 2% probability of malignancy that is widely accepted for these types of probably benign lesions," she said.

"Currently there is disagreement over whether cancer can be reliably excluded by breast core biopsy," said Dr. Leung. "The benefit of surgical excision is definitive tissue diagnosis and exclusion of cancer. The benefit of imaging surveillance is that it obviates unnecessary surgery, with its associated morbidity for nonmalignant lesions," Dr. Leung said. "This study provides evidence that imaging surveillance is appropriate for these patients," said Dr. Leung.

The incidence of benign papillomas without abnormal cells is uncommon --about 1.4% of imaging-guided core biopsies, noted Dr. Leung. Nevertheless, given the total number of core biopsies performed, the number of benign papillomas diagnosed is sufficiently high to warrant an evidence-based approach to their management. Papillomas are usually histologically complex lesions that are associated with a high degree of abnormal cells, she said.

The study is being presented May 3 at the American Roentgen Ray Society Annual Meeting in Vancouver, Canada.


Contact: Samantha Schmidt
American Roentgen Ray Society

Related medicine news :

1. New surgical technique for removing inoperable tumors of the abdomen
2. Study examines medicare use for Mohs micrographic surgery and surgical excision for skin cancer
3. Nonsurgical Method to Measure Brain Pressure Shows Promise
4. In children born with severe heart defect, surgical management has little effect on neuro outcomes
5. Does BMI affect post-surgical complications, survival in esophageal adenocarcinoma?
6. Pleurectomy/decortication proposed preferred surgical procedure
7. Drug Reduces Complications in Surgical Abortions: Study
8. Surgical breast biopsy not overused, study suggests
9. Regional surgical quality collaborative significantly improves surgical outcomes and reduces cost
10. Surgical robots to provide open-source platform for medical robotics research
11. University of Maryland Department of surgery continues to lead through surgical innovation
Post Your Comments:
(Date:10/13/2015)... , ... October 13, 2015 , ... ... a unique private messaging application, announced today a significant contract that will provide ... years. Independence plans to build on the growing success of its Relay program, ...
(Date:10/13/2015)... ... 2015 , ... A child without a healthy mouth is much more likely ... invisible aligner system, has joined with Global Dental Relief (GDR) to help ... treatment plan purchased, SmileCareClub will donate one clinic visit to a child in Kenya. ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... kind product that targets the unique health needs of new moms. Postnatal ... Pregnancy Association ( ), utilizes Nordic Naturals’ exclusive, new, ultra-concentrated omega-3 ...
(Date:10/13/2015)... ... , ... Tempe Dental Care, a leading Tempe dentists’ office, celebrates offering gentle, ... for more than 5 years. A leading cause of emergency room visits, school ... is not timely. , Sedation dentistry provides an anxiety-free dental experience ...
(Date:10/13/2015)... (PRWEB) , ... October 13, 2015 , ... According to ... Rose suffered an orbital fracture when a teammate accidentally elbowed him in the left ... Rose's recent eye injury is just one of a series of setbacks, including a ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... 2015 Attracting mid- to large-sized medical device companies ... Baltimore into a major medical device ... Maryland Technology Enterprise Institute (Mtech) . ... place to support innovation hubs and a thriving medical device ... "This study is important because we believe Baltimore ...
(Date:10/13/2015)... Fla. , Oct. 13, 2015   Vigilant ... of solutions that aid in the early detection and ... has awarded Vigilant,s founder and CEO, Matthew H.J. ... Year Award, which recognizes an entrepreneur who has made ... life sciences industry in the leadership of ...
(Date:10/13/2015)... DURHAM, N.C. , Oct. 13, 2015   ... from the DESSOLVE I and II trials of its ... MiStent SES ® ) were presented at the ... held in San Francisco , October ... in interventional cardiovascular medicine. MiStent SES was designed to ...
Breaking Medicine Technology: