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Surgery found effective for patients with aggressive prostate cancer
Date:9/27/2010

ROCHESTER, Minn. -- In one of the first studies to focus exclusively on the outcomes after treatment for patients with high-risk prostate cancer,(http://www.mayoclinic.org/prostate-cancer/) researchers have found that surgery provides high survival rates. Collaborating researchers at Mayo Clinic and Fox Chase Cancer Center (http://www.fccc.edu/) in Philadelphia discovered that patients with the most aggressive forms of prostate cancer who had radical prostatectomy procedures had a 10-year cancer-specific survival rate of 92 percent and an overall survival rate of 77 percent.

The cancer-specific survival rate for patients who had radiation therapy alone was 88 percent and the overall survival rate was 52 percent. The findings were presented today at the North Central Section of the American Urological Association's 84th Annual Meeting held in Chicago (http://www.ncsaua.org/).

"It's long been believed that patients with aggressive prostate cancer are not candidates for surgery," says Stephen Boorjian, M.D., (http://www.mayoclinic.org/bio/14373041.html) a Mayo Clinic urologist. "We found that surgery does provide excellent long-term cancer control for this type of prostate cancer. In addition, by allowing the targeted use of secondary therapies such as androgen deprivation, surgery offers the opportunity to avoid or at least delay the potentially adverse health consequences of these treatments."

Of the 1,847 patients with aggressive prostate cancer (as defined by the National Comprehensive Cancer Network) included in the study from 1988 to 2004, 1,238 underwent surgery at Mayo Clinic and 609 were treated with radiation therapy at Fox Chase Cancer Center. Of the 609 receiving radiation therapy, 344 also received androgen deprivation therapy.

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Contact: Amy Tieder
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

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