Navigation Links
Surgery complications linked to chemotherapy delay, U-M study finds
Date:12/8/2010

ANN ARBOR, Mich. Patients who have complications after colorectal cancer surgery are less likely to get chemotherapy, even when it is clearly recommended for their diagnosis, a new study from the University of Michigan Comprehensive Cancer Center finds.

In addition, patients with complications were more than twice as likely to have their chemotherapy delayed for more than 120 days after diagnosis or two months after surgery, which is considered the appropriate timeframe for receiving chemotherapy.

"Surgical complications are typically thought to be short-term problems, but our study suggests there is a clear link between downstream cancer care and complications that occur during surgery. This is critical because chemotherapy in this subset of colorectal cancer patients has clear lifesaving benefit," says lead study author Samantha Hendren, M.D., M.P.H., assistant professor of surgery at the U-M Medical School.

The study looked at data from 17,108 patients who had surgery for stage III colorectal cancer. Chemotherapy is recommended for all stage III colorectal cancer patients and has been shown to improve survival as much as 16 percent after five years. Patients were identified for the study from the Surveillance, Epidemiology and End Results-Medicare database, a large population-based registry.

Results of the study appear in the December issue of the journal Diseases of the Colon & Rectum.

Because chemotherapy stresses the body and slows healing, medical oncologists are generally reluctant to give chemotherapy to patients who are frail or unwell because of complications from surgery. Hendren also suggests that some patients may opt out of chemotherapy after experiencing surgical complications.

Complications include pneumonia, urinary tract infections, heart attack, wound infections, need for additional surgery or abscess drainage. Researchers believe that some of these complications can be prevented.

Nationally, variations exist among hospitals in use of chemotherapy for stage III colorectal cancer, and national quality guidelines focus on encouraging chemotherapy use. The researchers believe that surgical complications could be one factor that explains this disparity and urge hospitals to adopt quality measures to reduce complications.

"If we're going to try to improve compliance with chemotherapy guidelines, we need to be aware why patients are not getting it. Surgical complications could be part of that picture," says Hendren, noting that this will be the topic of her next study.


'/>"/>

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related medicine news :

1. Radiation After Surgery Lowers Chances of Breast Cancers Return
2. AAO-HNSF partners with SAGE to publish Otolaryngology-Head and Neck Surgery
3. Peripheral Arterial Surgery Outcomes Worse for Women: Study
4. Mayo Clinic study finds aggressive surgery is best for children with brain tumors
5. Assessment tool predicts blood clot risk after plastic surgery
6. Adding Surgery to Meds May Help Diabetics With Heart Disease
7. Hospital for Special Surgery scientists share advances in lupus and related conditions
8. 5-year results show keyhole bowel cancer surgery is safe and effective
9. Experts issue recommendations for treatment of post-bariatric surgery patients
10. Prognostic markers for prostate cancer patients who receive radiation after surgery
11. Lombardi research: Robotic radiosurgery offers palliative care for hilar lung tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... ... May 05, 2016 , ... An essential tool for researching ... certain Canadian provinces is now available from the International Association of Industrial Accident ... The report, Workers’ Compensation Laws as of January 1, 2016, is ...
(Date:5/5/2016)... (PRWEB) , ... May 05, 2016 , ... A recent ... continue to face challenges in getting employees to understand and use the free preventive ... of the nation’s leading non-profit business groups of large, self-insured public and private employers, ...
(Date:5/5/2016)... , ... May 05, 2016 , ... Vitenas Cosmetic Surgery ... Design Awards, presented by the American Institute of Architects and the Academy of Architecture ... the renowned Perkins+Will and Harrell Architects, opened to patients in October of 2014. ...
(Date:5/5/2016)... , ... May 05, 2016 , ... TIME for Kids ... – today announced a new partnership to reach nearly 1 million children with important ... an instant and is the leading cause of accidental death in children one to ...
(Date:5/5/2016)... ... 2016 , ... In order to increase comfort, convenience and ... Seattle-based steam bath and sauna manufacturer recently launched amerecConnect™ , a new ... app, developed for both smartphones and personal computers perfectly emulates that of the ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... -- Research and Markets has announced the ... Market Outlook 2020" report to their offering. ... technology has improved significantly in past years due to ... coming years. Many cancer drugs have been developed by ... also expected to be developed with its help. They ...
(Date:5/3/2016)... 3, 2016   BIOTRONIK , a leader ... Food and Drug Administration (FDA) approval of Iperia ... heart failure patients with access to diagnostic magnetic ... remote monitoring with daily automatic transmission and closed ... in response to physiological demands. ...
(Date:5/3/2016)... -- Pharmaceutical giant Johnson & Johnson has ... who says its talc-based powder products caused ovarian cancer. ... $5 million in compensatory damages and $50 million in ... ) , This is the second in ... the same court awarded $72 million to the family ...
Breaking Medicine Technology: