Navigation Links
Surgery and radiation improve survival for metastatic gastric cancer patients, Moffitt study shows
Date:2/27/2013

Researchers at Moffitt Cancer Center studied patients with metastatic gastric cancer and found that those who have both surgery and radiation have better survival than those who receive one or no form of treatment.

The study appeared in an online issue of Cancer.

"There were an estimated 21,000 new cases of gastric cancer in the United States in 2010 and 11,000 deaths from the disease," said Ravi Shridhar, M.D., Ph.D., of the Radiation Oncology Department at Moffitt. "Most gastric cancers are diagnosed at advanced stages, when surgery may not be an option."

Until now, there has been no data to address which treatment options offered the best survival rates for metastatic gastric cancer patients. Moffitt researchers analyzed metastatic gastric cancer cases from the Surveillance, Epidemiology and End Results (SEER) database to help determine which treatments options offer the best survival possibilities. Using data from 2004 to 2008, they divided 5,072 patient cases into four groups: those receiving either surgery or radiation, those receiving both, and those receiving no treatment.

"This study was the first SEER database study to suggest a survival benefit for patients undergoing both surgery and radiation in the management of metastatic gastric cancer," Shridhar explained. "Even in the metastatic setting, patients undergoing surgery had better survival if they received radiation therapy and had more than 15 lymph nodes removed."

According to the researchers, radiation therapy has been shown to be effective at reducing pain, obstruction and bleeding from gastric tumors, but there have been no reports on a potential survival benefit of radiation in metastatic gastric cancer. Several clinical trials for metastatic cancer using various chemotherapy regimens have shown median survivals range between eight to 14 months.

The current standard of care for metastatic gastric cancer is systemic chemotherapy. The researchers noted that while their study results are provocative, they should not be used to make general recommendations about surgery and radiation. Their findings should be used to form the basis for conducting clinical trials to assess the role of surgery and radiation for patients who have responded to chemotherapy.

"Every patient is going to be different," Shridhar said. "If a patient with metastatic gastric cancer is in good health and responds to chemotherapy, a discussion with radiation and surgical oncologists should take place to determine the role and sequence of radiation and surgery. If the patient has not responded to chemotherapy, surgery and radiation will likely hold no benefit."


'/>"/>

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute
Source:Eurekalert

Related medicine news :

1. The Triangle’s First Orthopaedic Ambulatory Surgery Center Officially Opens in Brier Creek
2. Dr. Stephen C. Hale Now Offering LANAP Periodontal Surgery for Texas City Gum Disease
3. Cleveland Clinic study shows bariatric surgery restores pancreatic function by targeting belly fat
4. San Luis Obispo, CA Dentist, Dr. Michael Colleran, Joins One Percent Of Dental Professionals To Offer The FDA Cleared Laser Surgery For Gum Disease
5. Atlanta Opthalmologist Interviewed About LASIK Surgery’s Life-Changing Effects
6. Milford, Ohio: Periodontists of the Ohio Valley Center for Periodontics & Implants Now Bring a Modern Gum Surgery Alternative to their Local Gum Disease Patients
7. Beautologie Plastic Surgery Now Accepts Insurance Plans for Breast Reduction Surgery
8. Does bariatric surgery impact medical costs associated with obesity?
9. Weight-Loss Surgery Wont Cut Obesity-Related Medical Costs: Study
10. US Drug Watchdog Now Urges Victims Of A Transvaginal Mesh, Tape Or Sling Repair Surgery That Failed To Call Them For The Names Of The Best Possible Women Lawyers
11. Fluorescent Tracer Lights Up Brain Tumor for Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with ... for the primary prevention of cardiovascular diseases during the 15th Annual Women’s ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading ... to advocate for action towards gender equality at their inaugural Summit in New York ... globe, and reached a social audience of over 3 million. To watch the Mobilize ...
(Date:10/13/2017)... ... 2017 , ... “The Journey: From the Mountains to the Mission Field”: the ... in the Philippines. “The Journey: From the Mountains to the Mission Field” is the ... She has taught all ages and currently teaches a class of ladies at her ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed a ... and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been ... standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, ... a medical article to the newly revamped Cosmetic Town journal section, ... hair transplant procedure known as Follicular Unit Extraction (FUE). , Dr. ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)...  In response to the nationwide opioid epidemic, ... (AAOMS) released prescribing recommendations that urge ibuprofen – ... a first-line therapy to manage a patient,s acute ... Recognizing the value and importance of the ... Acute and Postoperative Pain Management" stresses that practitioners ...
(Date:10/4/2017)... , Oct. 4, 2017 OBP ... self-contained, illuminating medical devices, today announced regulatory approval ... Surveillance Agency (or Agência Nacional de Vigilância Sanitária ... single-use, cordless surgical retractor with integrated LED light ... access, illumination and exposure of a tissue pocket ...
(Date:10/2/2017)...  AllianceRx Walgreens Prime, the combined central specialty pharmacy ... benefit manager Prime Therapeutics LLC (Prime), today officially began ... unveiling of new signage at its headquarters in ... a few other company-owned facilities across the country. This ... of whom will begin to see the AllianceRx Walgreens ...
Breaking Medicine Technology: