Navigation Links
Surgery and radiation improve survival for metastatic gastric cancer patients, Moffitt study shows
Date:2/27/2013

Researchers at Moffitt Cancer Center studied patients with metastatic gastric cancer and found that those who have both surgery and radiation have better survival than those who receive one or no form of treatment.

The study appeared in an online issue of Cancer.

"There were an estimated 21,000 new cases of gastric cancer in the United States in 2010 and 11,000 deaths from the disease," said Ravi Shridhar, M.D., Ph.D., of the Radiation Oncology Department at Moffitt. "Most gastric cancers are diagnosed at advanced stages, when surgery may not be an option."

Until now, there has been no data to address which treatment options offered the best survival rates for metastatic gastric cancer patients. Moffitt researchers analyzed metastatic gastric cancer cases from the Surveillance, Epidemiology and End Results (SEER) database to help determine which treatments options offer the best survival possibilities. Using data from 2004 to 2008, they divided 5,072 patient cases into four groups: those receiving either surgery or radiation, those receiving both, and those receiving no treatment.

"This study was the first SEER database study to suggest a survival benefit for patients undergoing both surgery and radiation in the management of metastatic gastric cancer," Shridhar explained. "Even in the metastatic setting, patients undergoing surgery had better survival if they received radiation therapy and had more than 15 lymph nodes removed."

According to the researchers, radiation therapy has been shown to be effective at reducing pain, obstruction and bleeding from gastric tumors, but there have been no reports on a potential survival benefit of radiation in metastatic gastric cancer. Several clinical trials for metastatic cancer using various chemotherapy regimens have shown median survivals range between eight to 14 months.

The current standard of care for metastatic gastric cancer is systemic chemotherapy. The researchers noted that while their study results are provocative, they should not be used to make general recommendations about surgery and radiation. Their findings should be used to form the basis for conducting clinical trials to assess the role of surgery and radiation for patients who have responded to chemotherapy.

"Every patient is going to be different," Shridhar said. "If a patient with metastatic gastric cancer is in good health and responds to chemotherapy, a discussion with radiation and surgical oncologists should take place to determine the role and sequence of radiation and surgery. If the patient has not responded to chemotherapy, surgery and radiation will likely hold no benefit."


'/>"/>

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute
Source:Eurekalert

Related medicine news :

1. The Triangle’s First Orthopaedic Ambulatory Surgery Center Officially Opens in Brier Creek
2. Dr. Stephen C. Hale Now Offering LANAP Periodontal Surgery for Texas City Gum Disease
3. Cleveland Clinic study shows bariatric surgery restores pancreatic function by targeting belly fat
4. San Luis Obispo, CA Dentist, Dr. Michael Colleran, Joins One Percent Of Dental Professionals To Offer The FDA Cleared Laser Surgery For Gum Disease
5. Atlanta Opthalmologist Interviewed About LASIK Surgery’s Life-Changing Effects
6. Milford, Ohio: Periodontists of the Ohio Valley Center for Periodontics & Implants Now Bring a Modern Gum Surgery Alternative to their Local Gum Disease Patients
7. Beautologie Plastic Surgery Now Accepts Insurance Plans for Breast Reduction Surgery
8. Does bariatric surgery impact medical costs associated with obesity?
9. Weight-Loss Surgery Wont Cut Obesity-Related Medical Costs: Study
10. US Drug Watchdog Now Urges Victims Of A Transvaginal Mesh, Tape Or Sling Repair Surgery That Failed To Call Them For The Names Of The Best Possible Women Lawyers
11. Fluorescent Tracer Lights Up Brain Tumor for Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/31/2016)... ... ... Phynd Technologies, Inc. announced recently the signing of three new hospitals: Meadows Regional ... – Somers Point, NJ. The new clients range in bed size from 57 to ... solution and its interoperability. , Houston Methodist is a leading academic medical center comprised ...
(Date:5/31/2016)... (PRWEB) , ... May 31, 2016 , ... Dr. Charles ... and Dentistry of New Jersey in the class of 1986, where he graduated in ... dentistry at his current location in Livingston since 1989. He has been a member ...
(Date:5/31/2016)... ... May 31, 2016 , ... Super Powder, a supplement produced by Prox Formulas ... and dedicated athletes, continues to transform the nutritional supplement industry by providing a safe, ... protein, branched-chain amino acids (BCAA), alkaline minerals, wheat grass, digestive enzymes, Omega 3’s, Vit ...
(Date:5/30/2016)... ... May 30, 2016 , ... Shaolin Institute officially starts ... 8-night special intensive summer training camp starts on June 17th on Shaolin Institute ... and children a fun and unique experience with an opportunity to learn KungFu ...
(Date:5/29/2016)... ... ... "With 30 unique self-animating web themed intros and complete control over customization, ... Christina Austin - CEO of Pixel Film Studios. , ProIntro Web Volume 3 ... Cut Pro X. Pixel Film Studios’ minimalistic titles allow users to add a sleek ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... , Deutschland und GERMANTOWN, Maryland ... Zusammenarbeit mit Therawis bedient dringenden ... Brustkrebs   QIAGEN N.V. (NASDAQ: ... heute bekannt, eine Lizenz- und Entwicklungsvereinbarung mit Therawis ... für die Onkologie eingegangen zu sein. Ein erstes ...
(Date:5/25/2016)... May 25, 2016 As illustrated ... earlier this month, the numbers and momentum of cannabis ... climb into the billions, more research and development push ... Edition State of Legal Marijuana Markets Report  from from ... firm, much of the increase in sector is attributed ...
(Date:5/25/2016)... India , May 25, 2016 ... Review, H1 2016"market research report that provides an ... with comparative analysis at various stages, therapeutics assessment ... of administration (RoA) and molecule type, along with ... It also reviews key players involved in the ...
Breaking Medicine Technology: