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Surgery Effective for Tough-to-Treat Epilepsy
Date:2/7/2012

TUESDAY, Feb. 7 (HealthDay News) -- Surgery can significantly improve seizure control and quality of life among people with epilepsy, according to a study stretching over 26 years.

"This study may be the longest follow-up of epilepsy surgery patients in that it spans three decades, during which there were several eras of neuroimaging [brain-scanning] techniques," said Dr. Cynthia Harden, chief of the division of epilepsy and electroencephalography at the Cushing Neuroscience Institute, part of North Shore-LIJ Health System in Great Neck, N.Y. She was not involved in the study.

The research team, led by Dr. Matthew Smyth with Washington University School of Medicine in St. Louis, argued that the findings could have an impact on the way the disease is treated.

As reported Feb. 7 in the journal Epilepsia, they followed 361 patients who had epilepsy surgery over the course of 26 years to determine how the operation affected their condition.

Although drug therapy remains the primary treatment option for people with epilepsy, the study's authors found that surgery stopped 48 percent of the patients from having seizures and improved the quality of life of 80 percent of those studied.

"In cases where medical [drug] therapy fails to control seizures, epilepsy surgery is a safe and effective treatment option," explained Smyth in a journal news release. "Despite the increase in the number of epilepsy surgeries performed, and reports in the medical literature of the success of surgery relative to medication, it remains an underutilized therapy for seizure control."

Smyth's team noted that surgical complications and death following epilepsy surgery decreased over the course of the study.

"Our findings demonstrate that the benefits of epilepsy surgery are sustained over long time periods," Smyth concluded. "Increased use of surgical intervention offers patients with epilepsy the possibility of long-t
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