Navigation Links
Surface bacteria maintain skin's healthy balance
Date:11/22/2009

On the skin's surface, bacteria are abundant, diverse and constant, but inflammation is undesirable. Research at the University of California, San Diego School of Medicine now shows that the normal bacteria living on the skin surface trigger a pathway that prevents excessive inflammation after injury.

"These germs are actually good for us," said Richard L. Gallo, MD, PhD, professor of medicine and pediatrics, chief of UCSD's Division of Dermatology and the Dermatology section of the Veterans Affairs San Diego Healthcare System.

The study, to be published in the advance on-line edition of Nature Medicine on November 22, was done in mice and in human cell cultures, primarily performed by post-doctoral fellow Yu Ping Lai .

"The exciting implications of Dr. Lai's work is that it provides a molecular basis to understand the 'hygiene hypothesis' and has uncovered elements of the wound repair response that were previously unknown. This may help us devise new therapeutic approaches for inflammatory skin diseases," said Gallo.

The so-called "hygiene hypothesis," first introduced in the late 1980s, suggests that a lack of early childhood exposure to infectious agents and microorganisms increases an individuals susceptibility to disease by changing how the immune system reacts to such "bacterial invaders." The hypothesis was first developed to explain why allergies like hay fever and eczema were less common in children from large families, who were presumably exposed to more infectious agents than others. It is also used to explain the higher incidence of allergic diseases in industrialized countries.

The skin's normal microflora the microscopic and usually harmless bacteria that live on the skin includes certain staphylococcal bacterial species that will induce an inflammatory response when they are introduced below the skin's surface, but do not initiate inflammation when present on the epidermis, or outer laye
'/>"/>

Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Diamond Honing Tool Technology: The New Standard in Surface Finishing of Hard Materials
2. Independent Study: OxiTitan VLR Antimicrobial Coating Kills Virus on Surfaces
3. Foldaway Pediatric Point of Care Table Provides Efficient Work Surface Without Compromising Space
4. EcoActive Surfaces Introduces OxiTitan VLR: New Light Powered Antimicrobial Coating Effective Against Viruses and Bacteria Indoors
5. Newly Patented Sterilization/Disinfection Method Reduces Risk of Microorganism Growth on Hard Surfaces
6. Harmful Bacteria May Hide on Soft Surfaces in Your Home
7. Oust(R) Surface Disinfectant & Air Sanitizer Effective Against H1N1
8. Nuvilex Advances Release of Citroxin(TM) Antiviral Surface Cleaner to Help Combat Swine Flu
9. Syracuse University researchers build a new surface material that resists biofilm growth
10. Surface Logix Raises $20 Million in Financing and Starts Phase 2b Clinical Trial of SLx-4090 in Dyslipidemia and Diabetes
11. FDA Clears New Skin and Surface Treatment Applicator for Use With Xofts Axxent(R) Electronic Brachytherapy (eBx) System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... B. E. Smith, the only full-service leadership ... retained to lead a national chief financial officer ... Park, Colo. The top executive search firm in the ... than 900 healthcare executives into organizations. , Estes ... access hospital and level IV trauma center, with a ...
(Date:12/19/2014)... 2014 Hands On Mobile Spa, has announced ... Spa On Wheels has been transformed into a utopia for ... world seems to disappear. The Virtual Tour showcases the beauty ... parties, corporate events and more. , The Virtual Tour shows ... which is actually an overhauled Winnebago. Marla Kaplan-Pelle, Director states ...
(Date:12/19/2014)... 2014 Slone Partners , ... medicine, healthcare information technology, and laboratory testing industries, ... Chief Operating Officer. The announcement comes after a ... a strengthened presence in Boston and several new ... and breathes the client experience," said Adam Slone, ...
(Date:12/19/2014)... The Hermitage Club at Haystack ... Vermont’s Deerfield Valley, announced today that it has unveiled ... songs. , Three time Grammy Award Winner Kenny ... followed by a trail naming ceremony. Hermitage Club Founder, ... “I’m Alright” the theme song for the movie soundtrack ...
(Date:12/19/2014)... Amy Norton HealthDay Reporter ... moms who were exposed to high levels of air pollution ... autism, a U.S. study suggests. Researchers found that of ... 2002, those exposed to the most air pollution during pregnancy ... developed autism. And exposure during the third trimester, specifically, showed ...
Breaking Medicine News(10 mins):Health News:Estes Park Medical Center Retains B. E. Smith to Recruit New Chief Financial Officer 2Health News:Estes Park Medical Center Retains B. E. Smith to Recruit New Chief Financial Officer 3Health News:A Virtual Tour Of Hands On Mobile Massage Spa Is Now Available 2Health News:A Virtual Tour Of Hands On Mobile Massage Spa Is Now Available 3Health News:Slone Partners Promotes Leslie Loveless to Chief Operating Officer 2Health News:The Hermitage Club Officially Names Four Ski Trails after Iconic Rock Songs by Grammy Award Winner Kenny Loggins 2Health News:Smog Exposure During Pregnancy Linked to Autism Risk 2Health News:Smog Exposure During Pregnancy Linked to Autism Risk 3
... , , ... provider of software and services to health plans and physician ... commitment to quality product development. DST Health Solutions received its ... for meeting the guidelines set forth by the International Organization ...
... , , , ... York State Department of Transportation announced that today, July 28, 2009, ... will be unhealthy, especially for sensitive individuals, such as children, seniors ... high levels of ground-level ozone pollution. The alert is issued for ...
... , ROCHESTER, N.Y., July 28 VirtualScopics, Inc. ... for clinical trials, today announced that on Wednesday, August 12, 2009 ... will host a conference call to discuss these results on Thursday, ... VirtualScopics, President and Chief Executive Officer, Jeff Markin, and ...
... , ANN ARBOR, Mich., July 28 ... as the vendor for the Treatment Cost Calculator, an application ... planned healthcare services. The Treatment Cost Calculator also shows consumers ... , Clear Choice is headquartered in Bend, ...
... , PITTSBURGH, July 28 Mylan Inc. (Nasdaq: ... release it issued on Sunday, the company proactively and as a ... the weekend to bring to its attention a recent news article. ... facility Monday morning and has determined that the baseless accusations in ...
... , BEDFORD, Mass., July 28 ... Company) (Nasdaq: HOLX ), a leading developer, manufacturer ... products dedicated to serving the healthcare needs of women, today ... treatment for women suffering from excessive menstrual bleeding--has passed the ...
Cached Medicine News:Health News:DST Health Solutions Achieves ISO 9001:2008 Certification 2Health News:Air Quality Action Day Declared for Today, July 28, 2009 2Health News:VirtualScopics Schedules Second Quarter 2009 Earnings Announcement 2Health News:Clear Choice Health Plans Selects Thomson Reuters to Deliver Healthcare Cost Information to Members - and Exceed State Transparency Requirements 2Health News:Clear Choice Health Plans Selects Thomson Reuters to Deliver Healthcare Cost Information to Members - and Exceed State Transparency Requirements 3Health News:Mylan Reports That the FDA Determined That All Accusations Were Unfounded 2Health News:Photos: One Million Patients Choose Hologic's NovaSure(R) System Over Hysterectomy 2Health News:Photos: One Million Patients Choose Hologic's NovaSure(R) System Over Hysterectomy 3Health News:Photos: One Million Patients Choose Hologic's NovaSure(R) System Over Hysterectomy 4Health News:Photos: One Million Patients Choose Hologic's NovaSure(R) System Over Hysterectomy 5
(Date:12/15/2014)... Research and Markets , ... has announced the addition of the "Cardiac Guidewires ... their offering. Global Guidewires sector is projected to ... America accounts for nearly 35% (2015) of ... claims approximately 25% (2018). Asia-Pacific ...
(Date:12/15/2014)... NEW YORK and HERZLIYA PITUACH, Israel ... the "Company") (NASDAQ: IMNP ) announced today that ... of the Board succeeding Dr. Daniel Teper who ... been a member of Immune,s Board of Directors since 2013. ... comments: "I am delighted to represent the interest of shareholders ...
(Date:12/15/2014)... N.Y. and BRIDGEWATER, N.J. ... (NASDAQ: REGN) and Sanofi US (EURONEXT: SAN and NYSE: ... disease organizations to launch Cholesterol Counts , an ... about cholesterol, their numbers, and the risks associated with ... visit www. CholesterolCounts .com to take a ...
Breaking Medicine Technology:Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 4Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 2Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 3Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 4Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 2Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 3Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 4Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 5Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 6
... Pharma ChemOutsourcing announced today that it is actively seeking VC,s to ... September 14-16, 2010 in NJ.   This is a brand new forum ... , , ... of so many successful biotech companies to attract VC,s," says Mark ...
... ,, BEIJING , July ... or the "Company") (NYSE: CCM ), operator of,the ... China ,today announced that it has filed its annual report ... Form 20-F with the U.S. Securities and Exchange,Commission on ...
Cached Medicine Technology:Pharma ChemOutsourcing Show Seeking VC's to Address 100 Biotech Companies at September Event in Long Branch, NJ 2Concord Medical Files 2009 Annual Report on Form 20-F 2