Navigation Links
Suppressing activity of common intestinal bacteria reduces tumor growth
Date:5/9/2010

t essentially consists of prophylactic surgery -- removal of the polyps before they turn cancerous.

"Right now, people with FAP don't have many options," said Raz. "They develop the cancer relatively early in life and the only treatment is surgery, often a total colectomy the removal of the entire colon. And that still doesn't preclude the possibility of developing tumors elsewhere in the body."

That's why the second part of the study was especially encouraging, Raz said. When researchers administered a protein enzyme called extracellular signal-related kinase or ERK, it appeared to suppress intestinal turmorigenesis in the mice, causing cancer proteins to degrade more rapidly and increasing the survival time of the mice. If the inhibiting enzyme, which is currently undergoing clinical trials elsewhere, proves to be safe and effective, researchers say it eventually could provide FAP patients with another option other than surgery.

"This is a clear case of nature and nurture in molecular biology," said Raz. "Nature is the host, who in some cases is going to be genetically predisposed to develop certain diseases. Nurture is the environment, which in this case is bacterial activity and its effects. The mechanism for what's happening here with these mice and tumor growth is very clear. We know what we want and need to do."


'/>"/>

Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Brooke Burke Named Spokeswoman for underWAY(TM), Americas First All Natural Appetite Suppressing Beverage & Thirst Quencher
2. Physical activity reduces the effect of the obesity gene in adolescents
3. IHRSA Expresses Its Ardent Support of America's First-Ever National Physical Activity Plan and Accepts Role as Co-Chair of Implementation Sub-Committee
4. Physical Activity Guidelines for Americans interpreted for practical use
5. Two New Phytochemicals with Anti-Inflammatory Activity Found in Noni Fruit
6. Language dysfunction in children may be due to epileptic brain activity
7. Pollen.com Reports Five U.S. Cities with Highest Pollen Activity -- Total Prescriptions for Allergy Medications 3.7% Higher than Last Year
8. Optovue Announces Formation of the EYE-GIVE Foundation for World-Wide Eye Care Philanthropy Activity
9. Siblings of Kids With Autism May Be Prone to Hyperactivity
10. Why do sexually experienced girls resume sexual activity after abstinence?
11. After a fight with a partner, brain activity predicts emotional resiliency
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... Columbus, Ohio (PRWEB) , ... August 28, 2015 ... ... Saturday’s Imagine No Malaria Day at the Zoo to celebrate children helping children, ... people and their congregations throughout West Ohio have contributed to the United Methodist ...
(Date:8/28/2015)... ... , ... For Dallas, the time is nearing for the annual Heart Walk, ... , The American Heart Association hosts their well-known Heart Walk to raise money in ... difference can be made. Walkers can participate in the cause and someone can also ...
(Date:8/28/2015)... ... August 28, 2015 , ... On May 30th, 2015, Best Drug Rehabilitation, ... the “Music With A Mission” benefit concert in Mendon, IL. Held in the Show ... money to support music education programs in the underfunded local school districts of Mendon ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... documenting and diagramming network and data center assets and audio-video devices, recently released ... Cisco Nexus 5000 Series, HP ProLiant Gen9, EMC VNX Series , Super Micro ...
(Date:8/28/2015)... Utah (PRWEB) , ... August 28, 2015 , ... ... awarded a three-year accreditation for its adolescent residential, counseling, day treatment and intensive ... that it meets international standards for quality and its pursuit of excellence. As ...
Breaking Medicine News(10 mins):Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2Health News:New Video Released on "Music With A Mission" Benefit Concert Headlining Artist Cadillac Three & Best Drug Rehabilitation 2Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 2Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 3Health News:West Ridge Academy Awarded CARF Three-Year Accrediation 2
... for tuberculosis has revealed that nearly 40% of the doctors ... levels// in those who work in TB clinics. The research ... is a growing problem worldwide. Russia is one country where ... the world's population are infected with the bacterium that causes ...
... breast cancer therapy drug tamoxifen, to another one exemestane//, could ... their findings in the online version of The Lancet, researchers ... and team, stood for changing treatments tracks to exemestane after ... reduced deaths by 17 percent. ,Their findings stem ...
... drug that aids patients who suffer from persistent iron overload ... ,Patients suffering from a rare genetic condition or ... transfusions. Generally these people are given a painful infusion at ... hours. ,But the new drug Exjade is an ...
... Carnegie Institution's Department of Plant Biology have discovered ... regulation—neighboring pore-like structures at the cell's surface physically ... nutrient, nitrogen. It is the first time scientists ... is essential to this regulation. Since plants, animals, ...
... new technique that uses ozone to preserve grapes could help ... reports Jennifer Rohn in Chemistry & Industry, the magazine of ... wine-making process to produce healthier wines without the added sulphites ... ,Mass-marketed grapes can remain in storage for months ...
... research currently underway brings hope of dramatic advances ... review//. The review reveals that new approaches in ... chemotherapy, and research on breast cancer vaccines may ... physician treating breast cancer patients. These new tools ...
Cached Medicine News:Health News:New Drug Therapy for Breast Cancer Offers Hope 2Health News:New Mechanism for Nutrient Uptake Discovered 2Health News:New Mechanism for Nutrient Uptake Discovered 3Health News:Grape Expectations for Healthier Wine 2Health News:Emerging Research Heralds New Era of Breast Cancer Management 2
(Date:8/28/2015)... , Aug. 28, 2015 ... addition of the "Investigation Report on China,s Tobramycin ... Tobramycin is a traditional antibiotic whose eye drop and ... treatment of potential infection or inflammation caused by eye ... are able to produce tobramycin, among which ...
(Date:8/28/2015)... , Aug. 28, 2015 Patterson Medical, ... (Nasdaq: PDCO ), is now an independent ... acquisition of Patterson Medical by Madison Dearborn Partners ... its name for a transition period before rebranding ... and sports medicine products.  With the focused resources ...
(Date:8/28/2015)... , Aug. 28, 2015 ... announced the addition of the "Investigation Report ... to their offering. Developed by Novo ... Novolog) is an important drug for the treatment ... as a fast- acting insulin analog, starts working ...
Breaking Medicine Technology:Investigation Report on China's Tobramycin Market, 2015-2019 2Patterson Medical Positioned for Continued Growth as a Newly Independent Company 2Patterson Medical Positioned for Continued Growth as a Newly Independent Company 3China Insulin Aspart Market Report 2010-2019 - Developed by Novo Nordisk 2
... , MT. LAUREL, N.J., Dec. 1 ... of technology-enabled clinical documentation services, today announced that the radiology ... SpeechQ for Radiology(TM), MedQuist,s real-time speech recognition system. The solution ... (RSNA) convention November 29 through December 2. ...
... , PISCATAWAY, N.J., Dec. 1 Siemens ... hearing instruments, announced its third annual partnership with Quota International,s ... 2010. , As part of the renewed partnership, Siemens is ... instruments to both children and young adults, age 23 years ...
Cached Medicine Technology:MedQuist Integrates Search Engine from Primordial with SpeechQ(TM) for Radiology 2Siemens Hearing Instruments Renews Quota Partnership to Give the Gift of Hearing to Children and Young Adults in Need 2Siemens Hearing Instruments Renews Quota Partnership to Give the Gift of Hearing to Children and Young Adults in Need 3
Welch Allyn introduced halogen HPX lamp technology to provide 30% more light output than previous halogen lamps. The mix of halogen and xenon gases provide whiter, longer lasting light - making your ...
RT-600 Refractor...
... Ultramatic Rx Master is designed ... of reliable service and give ... measurably improve procedures. It embodies ... and want most, including accuracy, ...
Occluder and Maddox Rod...
Medicine Products: