Navigation Links
Supply of Key Children's Vaccine Almost Back to Normal
Date:6/25/2009

CDC says production shortfalls that limited booster shots nearly over; Hib can cause bacterial meningitis

THURSDAY, June 25 (HealthDay News) -- A children's vaccine that's been in short supply for 18 months is now being produced at levels that allow its traditional widespread use, officials at the U.S. Centers for Disease Control and Prevention announced Thursday.

Beginning in December 2007, the agency recommended that parents forego booster shots for Haemophilus influenzae type B (Hib), an infection that can lead to bacterial meningitis. A booster shot of the vaccine was traditionally recommended for children at ages 12-15 months, but that was curtailed following a shortfall in supply from one of the two manufacturers of the vaccine, Merck & Co.

At the time, the CDC said the shortage meant that shots should be restricted to the initial series given to infants at 2, 4 and 6 months of age.

But as reported in the June 25 issue of the CDC journal Morbidity & Mortality Weekly Report, "the supply of Hib-containing vaccine is now sufficient to reinstate the on-time booster dose administration of Hib vaccine at 12-15 months for all children who completed the primary series."

While Merck continues to suspend its production of the Hib vaccine, another company, Sanofi Pasteur, plans to boost production of its two Hib vaccines, starting in July, to meet the demand, the CDC said.

However, supplies are still somewhat limited, and the CDC does not recommend that children who missed the booster shot during the past 18 months rush out now to get the vaccine. "Although supply is sufficient to reinstate the booster dose, there is currently only enough supply for limited catchup," the CDC noted. Parents of children who missed the booster shot at 12 to 15 months should wait until their "next routinely scheduled visit or medical encounter" and discuss the situation and their particular child's need for the shot with their doctor, the CDC said.

The CDC also noted that many children may have received Hib immunization through certain combination vaccines such as the DTaP-IPV/Hib (Pentacel), so physicians need to assess this carefully "to ensure appropriate coverage while minimizing extra doses of unneeded vaccine."

Last November, CDC officials said the Hib vaccine shortfall had caused them to monitor Hib infections. At the time, the agency said it had not yet seen any increase in cases. However, it said that stepped-up surveillance was important since the vaccine had virtually eliminated Hib infections in the United States since its introduction in 1988. Before the introduction of the vaccine, some 20,000 U.S. children would get serious and sometime fatal Hib infections each year, the CDC said.

Hib infection can cause a variety of illnesses, including meningitis (inflammation of the membranes covering the spinal column and brain), blood stream infections and pneumonia, according to the CDC. Hib is not a cause of the seasonal flu.

"The shortage is not serious but it is concerning," Michael Jackson, an epidemiologist with the CDC, said in November.

The shortfall was caused by Merck's recall of certain lots of Hib conjugate vaccine, followed by a suspension of production beginning in December 2007. At the time, Merck spokeswoman Amy Rose said that problems with the vaccine's sterilization process necessitated recalling the vaccine and then stopping production. The vaccines are marketed as PedvaxHIB and Comvax.

The fact that Sanofi-Pasteur makes the Hib vaccine rendered the shortfall less severe, Jackson said.

He noted that tracking Hib cases isn't easy. There are many different types of influenzae and there are many steps involved in testing and reporting the various types, so information often gets lost along the way, he said.

"The information we are getting at CDC is that we are missing about 40 percent of cases," Jackson said in November. "That's a little worrisome because that's 40 percent of people we don't know if they have type b, which is the vaccine-preventable one, the one we are really worried about, or if they have something else. It makes it harder for us to see changes in Hib if there really is something going on in the population."

Dr. Marc Siegel, an associate professor of medicine at New York University School of Medicine, said at the time that parents whose children missed the booster shot shouldn't panic.

"There used to be 20,000 cases a year, but the vaccine has brought it to less than 100," Siegel said. "The numbers remain small. We've almost stamped this thing out with the vaccine, so don't assume your kid is going to get it."

More information

For more on Hib disease, visit the CDC.



SOURCES: Michael Jackson, Ph.D., epidemiologist, U.S. Centers for Disease Control and Prevention, Atlanta; Amy Rose, spokeswoman, Merck & Co., Whitehouse Station, N.J.; Marc Siegel, M.D., associate professor, medicine, New York University School of Medicine, New York City; June 26, 2009, and Nov. 21, 2008, Morbidity and Mortality Weekly Report


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. AWWA, National Association of Water and Sanitation of Mexico, Agree to Share Expertise and Resources for Improved Water Supply
2. American Red Cross Issues Blood Supply Alert
3. Wedgewood Pharmacy and Midwest Veterinary Supply Sign New Agency Agreement
4. Martek Signs Multi-Year Infant Formula License and Supply Agreement with Alter Farmacia
5. Simplex Diabetic Supply, Inc. Secures $50 Million in Growth Equity from New Enterprise Associates
6. Dieticians & Nutritionists Report Decreased Confidence in Food Supply
7. Substantial costs and underreporting of dengue fever, concerns about blood supply face US
8. Osteotech Completes Tissue Supply Agreement With LifeNet Health
9. Pall launches new products to increase supply of safe blood
10. DoD and VA to Reduce Healthcare Supply Chain Costs
11. Novavax and Allergan Terminate Manufacturing Supply Agreement for Estrasorb
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Supply of Key Children's Vaccine Almost Back to Normal
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to ... of individuals in the United States and Canada wear eyeglasses. Once considered to be ... vision and make a fashion statement. Even celebrities use glasses as a way of ...
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media ... give their videos a whole new perspective by using the title layers in ... Studios. , ProSlice Levels contains over 30 Different presets to choose from. ...
(Date:6/26/2016)... Birmingham, Lake Orion, Clarkston, Michigan (PRWEB) , ... ... ... their direction with respect to fertility once they have been diagnosed with endometriosis. ... for tolerable intercourse but they also require a comprehensive approach that can help ...
(Date:6/25/2016)... ... ... Bruton Memorial Library on June 21 due to a possible lice infestation, as reported by ... lice: the parasite’s ability to live away from a human host, and to infest common ... the event that lice have simply gotten out of control. , As lice are a ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... As a ... Magna Cum Laude and his M.D from the David Geffen School of Medicine at ... returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 The Academy of Managed Care Pharmacy ... that would allow biopharmaceutical companies to more easily share ... formulary and coverage decisions, a move that addresses the ... The recommendations address restrictions in the sharing ... drug label, a prohibition that hinders decision makers from ...
(Date:6/24/2016)... Mass. and SAN CLEMENTE, Calif. , ... California -based mobile pulmonary function testing company, is now able ... PFT devices developed by ndd Medical Technologies , Inc. ... testing done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® ... , can get any needed testing done in the comfort ...
(Date:6/24/2016)... PUNE, India , June 24, 2016 ... "Pen Needles Market by Type (Standard Pen Needles, Safety ... 12mm), Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase ... published by MarketsandMarkets, This report studies the market for ... is expected to reach USD 2.81 Billion by 2021 ...
Breaking Medicine Technology: