Navigation Links
Supercomputer reveals new details behind drug-processing protein model
Date:12/6/2011

ted a higher number of water molecules would be present in the enzyme.

"We found that even though there can be many water molecules -- up to 12 at a given time that get in and out very quickly -- if you look at the average, those water molecules prefer to be at a certain location that corresponds to what you see in the crystal structure," Miao said. "It's a very dynamic hydration process that we are exploring with a combination of neutron scattering experiments and simulation."

The simulation research is published in Biophysical Journal as "Active-Site Hydration and Water Diffusion in Cytochrome P450cam: A Highly Dynamic Process."


'/>"/>
Contact: Morgan McCorkle
mccorkleml@ornl.gov
865-574-7308
DOE/Oak Ridge National Laboratory
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Harnessing the Web and supercomputers to track pathogens as they evolve
2. First large-scale study of pain reveals risk factors
3. Landmark survey reveals that most women who are done having children do not discuss their options with their OB/GYNs
4. Combined arterial imaging technology reveals both structural and metabolic details
5. Modern Technology Reveals Clues From Egyptian Mummy
6. Analysis reveals malaria, other diseases as ancient, adaptive and persistent foes
7. Study reveals details of alternative splicing circuitry that promotes cancers Warburg effect
8. The freshman 15 is just a myth, nationwide study reveals
9. Dopamine release in human brain tracked at microsecond timescale reveals decision-making
10. Blood vessel mapping reveals 4 new ZIP codes
11. Gene Mapping Reveals Clues to Bedbugs Pesticide Resistance
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Supercomputer reveals new details behind drug-processing protein model
(Date:8/22/2014)... A national leader in home delivery of medical ... to grow. , Headquarters for the provider of sterile-use catheters ... at 8516 N.W. Expressway in Oklahoma City. , Rapid ... best places to work by OKCBiz magazine – demanded more ... in the past two years, and staff count grew 30 ...
(Date:8/22/2014)... 22, 2014 Menstrual leaks risk stains ... Sunrise, Fla., decided that there needed to be a ... use and producible in design variations, the Safety Net ... leaks, which avoids embarrassment and promotes peace of mind. ... pads. , The original design was submitted to the ...
(Date:8/22/2014)... FRIDAY, Aug. 22, 2014 (HealthDay News) -- Counseling may ... a large-scale review finds. Researchers analyzed 66 studies ... of whom were at high risk for drinking problems. ... session, while participants in the rest of the studies ... individual sessions. A counseling technique called motivational interviewing ...
(Date:8/22/2014)... Aug. 22, 2014 (HealthDay News) -- College can be a ... of things they can do to make the most of ... time to adjust, explore, meet new people and learn to ... of student wellness and assessment at St. John,s University in ... "Not all learning takes place in the classroom. College is ...
(Date:8/22/2014)... TORONTO, Aug. 22, 2014 Women with severe disabilities ... less often than women with no disabilities or no ... are also screened less often than women with moderate ... to Dr. Sara Guilcher, an affiliate scientist with the ... , Dr. Guilcher said women with disabilities often have ...
Breaking Medicine News(10 mins):Health News:Fast-growing 180 Medical Moves Into New 60,000-square-foot Office in Oklahoma City 2Health News:Counseling Does Little to Deter Youth Drinking, Review Finds 2Health News:College Prep 101 2Health News:Women with severe, chronic health issues are screened for breast cancer less often 2
... greater bronchial responsiveness (BR) in people with certain common ... to cats. This suggests that reduced exposure to cats ... specific allergies. ,This was an unexpected finding, ... We presupposed that we would find increased responsiveness only ...
... dice and hope they come up seven: on Saturday thousands of ... the lucky number holds the key to marital bliss. ... to get married on Saturday, July 7, 2007 -- 7/7/7 -- ... ,In small chapels that have hosted weddings for decades and at ...
... influenza virus has been a pursuit of both historical and ... devastating single disease outbreak in modern history, and examining the ... prevent, future pandemics. ,When the complete sequence ... a watershed event for influenza researchers worldwide. ,In ...
... research from British Columbia found that aboriginal people who ... to use methadone maintenance therapy for treatment of ... colleagues evaluated factors associated with use of methadone maintenance ... to November 2005. At enrolment, 12.4% of Aboriginal participants ...
... Albert Einstein College of Medicine of Yeshiva University concluded ... likely to suffer from migraine headaches than teens from ... the July 3rd issue of Neurology, suggest that factors ... access to medical care, for example increase the prevalence ...
... Glasgow University and Baylor College of Medicine uncover 2 ... into the development of this potentially lethal disease. ... nonmelanoma skin cancer, which is the most common type ... in the USA each year. ,Mutations in ...
Cached Medicine News:Health News:Cat Exposure Increases Bronchial Responsiveness 2Health News:Will Seven Be the Lucky Number for Las Vegas Newlyweds? 2Health News:Influenza Virus Samples of 1918 2Health News:Low Income Family Adolescents Suffer Migraine 2Health News:Skin Cancer can Be Triggered by P53 Mutation 2
(Date:8/21/2014)... Aug. 21, 2014 /CNW/ - Eisai Limited is pleased to ... the first-of-its-kind comic book available in Canada ... designed specifically to educate children and their parents about epilepsy, ... affecting more than 300,000 Canadians. Eisai is guided by ... , in which the patient is central – there was ...
(Date:8/21/2014)... CHARLOTTE, N.C. , Aug. 21, 2014 /PRNewswire-iReach/ ... Home Medical Equipment, Inc. for the third straight ... annual Inc. 500|5000, an exclusive ranking of the ... most comprehensive look at the most important segment ... Yelp, Pandora, Timberland, Dell, Domino,s Pizza, LinkedIn, Zillow, ...
(Date:8/21/2014)...  Seventy-one percent of Americans believe the abuse of strong ... health and safety issue in the United States ... by Repass & Partners, a Cincinnati ... severity of the prescription medication abuse problem and the need ... health situation facing our country," Rex Repass , CEO ...
Breaking Medicine Technology:Eisai Pleased to Support Canadian Epilepsy Alliance Comic Book that Teaches Children About Epilepsy 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3Consumers Desperate For Measures To Curb Prescription Drug Abuse 2Consumers Desperate For Measures To Curb Prescription Drug Abuse 3
... Graham-Field has been developing ... than 58 years. Our medical-surgical ... reputation for innovation, quality and ... brands include the Labtron® line ...
... Air Entrainment Nebulizers deliver particulate humidity in ... your chronic secretion patients. For your convenience, ... existing supply of sterile water., ,The ... FiO2's of 20-50% with a total flow ...
... metered dose inhalers., ,ACE ensures prompt, ... canisters. Its versatile design allows it to ... conjunction with an endotracheal airway or resuscitation ... may also be used in conjunction with ...
... Airial Handheld Ultrasonic Nebulizer has ... This compact, portable, and lightweight ... fast & quite treatments operating ... or DC auto adapter. , ...
Medicine Products: