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'Superbug' breast infections controllable in nursing mothers, UT Southwestern researchers find
Date:8/30/2008

DALLAS Aug. 31, 2008 Many nursing mothers who have been hospitalized for breast abscesses are afflicted with the "superbug" methicillin-resistant Staphylococcus aureus, or MRSA, but according to new research by UT Southwestern Medical Center physicians, conservative treatment can deal with the problem.

The study focused on hospitalized women with mastitis, and showed that MRSA was much more likely to be found in those who had both mastitis (an inflammation of the milk glands) and abscesses (pockets of infection).

"The take-home message is that a patient with mastitis does not necessarily need an antibiotic against MRSA," said Dr. George Wendel, professor of obstetrics and gynecology and senior author of the study, which appears in the September issue of the journal Obstetrics and Gynecology. "She will improve with a less specific antibiotic as long as she also empties her breasts, either through feeding or pumping, and if there's an abscess, gets it treated."

The study also showed that if a nursing mother has an abscess, she does not immediately need antibiotics against MRSA, but can be switched to them if tests reveal she has MRSA.

The study was designed to determine which antibiotic treatment is best for severe cases of mastitis, which can be caused by clogged milk ducts with or without infection, and breast abscesses, which are caused by bacterial infections, generally by aureus. There are many strains of staph, one of which is MRSA.

Treating mastitis or breast abscesses immediately with powerful drugs that fight MRSA carries a risk of creating even more antibiotic-resistant strains of staph, Dr. Wendel said.

"The physician can take the time to test the patient to determine what kind of bacteria she has," Dr. Wendel said. "We found that you're not going to put the patient at a disadvantage if you start her on antibiotics while you wait for culture results, then switch her to more powe
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Contact: Aline McKenzie
aline.mckenzie@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

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