novel, oral, multi-targeted tyrosine kinase inhibitor (TKI). The
study is also open to accrual at South Texas Accelerated Research
Therapeutics (START) in San Antonio, Texas. The trial is expected to
enroll up to 30 patients at the two study centers. The Phase I trial
is an accelerated titration dose-escalation study designed to assess
the safety and tolerability of MP470, and to determine the maximum
tolerated dose of the compound in patients with advanced-stage solid
tumors. Additionally, the Company will assess pharmacokinetic and
biomarker data from the study to assist in designing follow-on
clinical studies for the use of MP470 as a single agent and in
combination treatment modalities.
August 2007:
-- The Company announced the retirement of Audrey F. Jakubowski, Ph.D.,
Chief Regulatory and Quality Officer. Dr. Jakubowski's primary
responsibilities were transitioned to David S. Smith, Ph.D., who
joined SuperGen in March 2007 as Vice President, Regulatory and
Quality Affairs. Most recently, Dr. Smith was Senior Director,
Regulatory Strategy at Wyeth Consumer Healthcare.
Conference Call Information
SuperGen will host a conference call to discuss the results of the 2007 third quarter today at 1:30 p.m. PT / 4:30 p.m. ET. A live webcast of the conference call is accessible via the investor relations section of the Company's Web site at http://ir.supergen.com. A webcast replay of the conference call will be available for 90 days.
About SuperGen
Based in Dublin, Calif., SuperGen Inc. is a pharmaceutical company
dedicated to the discovery, rapid development and commercialization of
therapies for solid tumors and hematological malignancies. SuperGen is
developing a
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