Navigation Links
Sunlight exposure plus low antioxidant levels may place older adults at risk for eye disease
Date:10/13/2008

A European study suggests that the combination of low plasma levels of antioxidants and blue light exposure from the sun is associated with certain forms of the eye disease age-related macular degeneration (AMD), according to a report in the October issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

"The retina is vulnerable to the damaging effects of light," the authors write as background information in the article. "While wavelengths in the UV radiation range are largely absorbed by the cornea and lens, the retina is exposed to visible light, including blue light." Animal and laboratory studies suggest blue light may damage the retina and contribute to the development of AMD, which occurs when the area of the retina (macula) responsible for sharp vision deteriorates.

Antioxidant enzymesincluding vitamins C and E, the carotenoids (lutein and zeaxanthin) and zincmay protect against the harmful effects of blue light on the retina. Astrid E. Fletcher, Ph.D., of the London School of Hygiene & Tropical Medicine, and colleagues measured levels of these nutrients in the blood of 4,753 older adults (average age 73.2) who were part of the European Eye Study. Participants also were interviewed about their lifetime sunlight exposure and had photographs taken of their retinas to detect AMD.

Of the 4,400 participants with complete information available, 2,117 did not have AMD, 101 had neovascular (advanced, involving the formation of new blood vessels) AMD and 2,182 had early-stage AMD. Overall, there was no association between blue light exposure and neovascular or early AMD. However, blue light exposure was associated with neovascular AMD in the one-fourth of individuals with lowest antioxidant levels. "In particular, the combination of blue light exposure in the presence of low levels of zeaxanthin, alpha-tocopherol [vitamin E] and vitamin C was associated with a nearly four-fold odds ratio of neovascular AMD," the authors write.

Key recommendations from the results include ensuring the intake of key antioxidants, which can be accomplished by consuming recommended dietary intake levels of vitamin C and zinc and increasing consumption of carotenoid-rich fruits and vegetables, the authors note. In addition, individuals should take steps to reduce the exposure of the retina to blue light, such as wearing broad-brimmed hats and sunglasses when outdoors.

"In the absence of cost-effective screening methods to identify people in the population with early AMD, we suggest that recommendations on ocular protection and diet target the general population, especially middle-aged people," they conclude.


'/>"/>

Contact: Astrid E. Fletcher, Ph.D.
astrid.fletcher@lshtm.ac.uk
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Sunlight, Vitamin D May Cut Kids Diabetes Risk
2. Sunlight Helps Put Lung Cancer in the Shade
3. A Little Wine, Sunlight Help Boost Womens Health
4. Exposure to sunlight may decrease risk of advanced breast cancer by half
5. As Sunlight Fades, Look Out for SAD
6. Cadmium Exposure Tied to Lung Disease
7. Heat Exposure a Dangerous Summer Threat
8. Prenatal drug exposure linked to sleep problems in children
9. UC research shows risk of ALS exposure in Gulf War veterans is time limited
10. Long-term pesticide exposure may increase risk of diabetes
11. Exposure Therapy Effective in Preventing Post-Traumatic Stress
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2017)... ... ... In any business, follow up is critical to success. It is the ... treatment, there will always be some patients who can’t or won’t make a immediate ... when it comes to presenting treatment. After the patient leaves, most practices end ...
(Date:5/26/2017)... NEW YORK, NY (PRWEB) , ... May 26, ... ... Advisory Board (SAB) met this week to review more than eighty-nine grant ... both experienced and emerging young scientists in the Parkinson’s field.     , The American ...
(Date:5/26/2017)... ... May 26, 2017 , ... Somnoware, a leading ... sleep monitor with its Somnoware Sleep Device Interface (SDI). Somnoware SDI is a ... operations. With this platform, initializing devices and importing studies are just one-click operations. ...
(Date:5/26/2017)... ... ... On May 24, the Congressional Budget Office (CBO) projected that the amended ... would result in 23 million Americans losing their health insurance by 2026 as compared ... Affordable Care Act (ACA). , “It is clear from the CBO analysis that ...
(Date:5/26/2017)... ... ... Lowe acts as host and helps educate and inform the public using the “Informed” ... reconnect with America as it explores some of the best places to hike and ... inventive new place for a family vacation, and have discovered hiking. Many will agree ...
Breaking Medicine News(10 mins):
(Date:5/18/2017)... -- Bayer announced today that the latest research from across ... 53 rd Annual Meeting of the American Society ... Chicago . The ... and thyroid cancers, as well as lymphomas, and includes ... of copanlisib in patients with relapsed or refractory follicular ...
(Date:5/11/2017)... -- Thornhill Research Inc. ( Toronto, Ontario, Canada ... five-year, firm-fixed-priced, indefinite-quantity/indefinite-delivery contract by the U.S. Department ... ( Ottawa, Ontario, Canada ) to ... to patients requiring emergency medical procedures in a ... have been a longtime partner with Thornhill Research ...
(Date:5/10/2017)... 10, 2017 Radiology has become the number ... have also spiraled to the number one ranking as ... than ever before as the most complete and reliable ... with lower back pain an MRI may confirm a ... pain, resulting in entirely different treatment protocols.  In these ...
Breaking Medicine Technology: