Navigation Links
Sunlight exposure plus low antioxidant levels may place older adults at risk for eye disease
Date:10/13/2008

A European study suggests that the combination of low plasma levels of antioxidants and blue light exposure from the sun is associated with certain forms of the eye disease age-related macular degeneration (AMD), according to a report in the October issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

"The retina is vulnerable to the damaging effects of light," the authors write as background information in the article. "While wavelengths in the UV radiation range are largely absorbed by the cornea and lens, the retina is exposed to visible light, including blue light." Animal and laboratory studies suggest blue light may damage the retina and contribute to the development of AMD, which occurs when the area of the retina (macula) responsible for sharp vision deteriorates.

Antioxidant enzymesincluding vitamins C and E, the carotenoids (lutein and zeaxanthin) and zincmay protect against the harmful effects of blue light on the retina. Astrid E. Fletcher, Ph.D., of the London School of Hygiene & Tropical Medicine, and colleagues measured levels of these nutrients in the blood of 4,753 older adults (average age 73.2) who were part of the European Eye Study. Participants also were interviewed about their lifetime sunlight exposure and had photographs taken of their retinas to detect AMD.

Of the 4,400 participants with complete information available, 2,117 did not have AMD, 101 had neovascular (advanced, involving the formation of new blood vessels) AMD and 2,182 had early-stage AMD. Overall, there was no association between blue light exposure and neovascular or early AMD. However, blue light exposure was associated with neovascular AMD in the one-fourth of individuals with lowest antioxidant levels. "In particular, the combination of blue light exposure in the presence of low levels of zeaxanthin, alpha-tocopherol [vitamin E] and vitamin C was associated with a nearly four-fold odds ratio of neovascular AMD," the authors write.

Key recommendations from the results include ensuring the intake of key antioxidants, which can be accomplished by consuming recommended dietary intake levels of vitamin C and zinc and increasing consumption of carotenoid-rich fruits and vegetables, the authors note. In addition, individuals should take steps to reduce the exposure of the retina to blue light, such as wearing broad-brimmed hats and sunglasses when outdoors.

"In the absence of cost-effective screening methods to identify people in the population with early AMD, we suggest that recommendations on ocular protection and diet target the general population, especially middle-aged people," they conclude.


'/>"/>

Contact: Astrid E. Fletcher, Ph.D.
astrid.fletcher@lshtm.ac.uk
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Sunlight, Vitamin D May Cut Kids Diabetes Risk
2. Sunlight Helps Put Lung Cancer in the Shade
3. A Little Wine, Sunlight Help Boost Womens Health
4. Exposure to sunlight may decrease risk of advanced breast cancer by half
5. As Sunlight Fades, Look Out for SAD
6. Cadmium Exposure Tied to Lung Disease
7. Heat Exposure a Dangerous Summer Threat
8. Prenatal drug exposure linked to sleep problems in children
9. UC research shows risk of ALS exposure in Gulf War veterans is time limited
10. Long-term pesticide exposure may increase risk of diabetes
11. Exposure Therapy Effective in Preventing Post-Traumatic Stress
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida ... their peers for this recognition are considered among the top 2 percent of lawyers ... as members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, ... journal articles published in Emergency Medicine Practice and Pediatric Emergency Medicine ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) ... held on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, ... dedicated to helping service members that have been wounded in battle and their families. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Southern Illinois University School ... for the Illinois State Dental Society (ISDS) Foundation’s Mission of Mercy (MOM). They ... Center in Collinsville. , They expect to treat approximately 2,000 patients ...
(Date:6/23/2016)... ... June 23, 2016 , ... An article ... a possible link between head and neck cancer in individuals with unhealthy oral hygiene ... were evaluated based on whether they had gum disease, brushed their teeth on a ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 , , , ... 7, 2016 , , , , LOCATION: , , , ... , , , EXPERT PANELISTS:  , , , Frost & Sullivan,s ... Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program ... global pharmaceutical industry is witnessing an exceptional era. Several new demand ...
(Date:6/23/2016)... 2016 The vast majority of dialysis patients ... Treatments are usually 3 times a week, with treatment ... travel time, equipment preparation and wait time.  This regimen ... for patients who are elderly and frail.  Many elderly ... rehabilitation centers for some duration of time. ...
(Date:6/23/2016)... 23, 2016 Leading BioSciences Inc., a ... conditions resulting from a breakdown of the mucosal ... Greg Doyle as chief executive officer. Mr. ... management team and board of directors, previously served ... He will provide continued leadership and strategic direction ...
Breaking Medicine Technology: