Sunesis Pharmaceuticals' SNS-595 Shows Clinical Activity in Patients With Relapsed or Refractory Acute Leukemias; Data Presented in Oral Session at 49th Annual Meeting of the American Society of ...( Conference Call Scheduled for 4:00 ...),Health

Conference Call Scheduled for 4:00 p.m. Eastern Time to Review Clinical Trial Results for SNS-595 and Non-clinical Data for SNS-032 Presented at

the ASH Meeting

ATLANTA, Dec. 10 /PRNewswire-FirstCall/ -- Sunesis Pharmaceuticals, Inc. (Nasdaq: SNSS), a clinical-stage biopharmaceutical company developing novel anticancer therapeutics, presented positive results for SNS-595 in relapsed or refractory acute leukemia patients in an oral session by Jeffrey Lancet, M.D, Assistant Professor, Division of Hematologic Malignancies at the H. Lee Moffitt Cancer Center & Research Institute, at the 49th Annual Meeting of the American Society of Hematology (ASH) in Atlanta, Georgia. In a Phase 1 clinical trial, SNS-595 was generally well tolerated with anti-leukemic clinical activity when administered either once- or twice-weekly at biologically active doses.

In addition, non-clinical data showing that SNS-032 induces apoptosis in chronic lymphocytic leukemia (CLL) cells are being presented by William Plunkett, Ph.D., Professor and Chief, Section of Molecular and Cellular Oncology at the University of Texas M. D. Anderson, in a poster session. SNS-032 is currently in a Phase 1 clinical trial in patients with CLL or multiple myeloma.

Sunesis management will host a conference call today at 4:00 p.m. Eastern time to review the SNS-595 and SNS-032 data presented at the ASH meeting. Drs. Lancet and Plunkett will join management on the call.

Oral Presentation: A Phase 1b Open-Label Study of the Novel DNA Replication Inhibitor SNS-595 in Refractory Acute Leukemia (Abstract #442)

SNS-595, a first-in-class naphthyridine analog that intercalates DNA and poisons topoisomerase II causing selective DNA
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