Navigation Links
'Suicide' Genes Help Slow Ovarian Tumor Growth in Mice
Date:7/30/2009

Treatment could be tested in women within 18 to 24 months, expert suggests

THURSDAY, July 30 (HealthDay News) -- Treatment with "suicide" genes slowed ovarian tumor growth in mice and may one day offer a way to treat late-stage ovarian cancer in women, U.S. scientists say.

Currently, there is no effective treatment for advanced ovarian cancer that has recurred after surgery and primary chemotherapy, according to a news release from the American Association for Cancer Research.

In the laboratory experiments on mice, the researchers found that nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells significantly slowed the growth of ovarian tumors. The findings appear online in the journal Cancer Research.

"This report is definitely a reason to hope," lead researcher Janet Sawicki, a professor at the Lankenau Institute for Medical Research, said in the news release. "We now have a potential new therapy for the treatment of advanced ovarian cancer that has promise for targeting tumor cells and leaving healthy cells healthy."

The new treatment, which could be tested on humans within 18 to 24 months, could prove to be a significant advance in targeted therapy for cancer, according to Dr. Edward Sausville, an associate editor of Cancer Research and associate director for clinical research at the Greenebaum Cancer Center at the University of Maryland.

"In oncology we have been studying ways to kill tumors for a long time, but much of this has run up against the real estate principle of location, location, location. In other words, an effective therapy is not effective if it cannot get to the target," Sausville said in the news release.

He noted that the approach described in this study offers multiple ways to target ovarian cancer cells.

More information

The American Cancer Society has more about ovarian cancer.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, July 30, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth
2. Feeling Blue Suicide Prevention Council Partners With the National Institute of Mental Health
3. Financial crisis increases suicides and homicides
4. VAs Suicide Prevention Message Carried on 21,000 Buses
5. Almost Quarter of Suicides Involve Intoxication
6. Sedatives Increase Suicide Risk Among Elderly
7. Fred A. Baughman Jr., MD Announces: Vets Sudden Cardiac Deaths Are Not Suicides or Overdoses
8. Worries About Weight Are Tied to Teen Suicide Tries
9. Americans United for Life Represents 28 Bipartisan Montana Legislators Arguing Assisted Suicide Not a Right
10. Team Uncovers Discrepancy in Death Certificates Listing Suicide
11. Death Certificates Incomplete for Suicide Victims
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Suicide' Genes Help Slow Ovarian Tumor Growth in Mice
(Date:3/28/2017)... , ... March 28, 2017 , ... ... by physicians, announced today the launch of a free, public-facing tool for analyzing ... Analyzer (VCA) was developed to provide comparative information to patients, providers, insurers and ...
(Date:3/28/2017)... ... , ... Usually, the impending arrival of warmer weather means the gleeful banishment ... double chin, this means more anxiety than elation. The cosmetic dermatology experts at Cosmetic ... double chin is undesirable,” Dr. Goldman said, “but it seems doubly so when the ...
(Date:3/28/2017)... Conn. (PRWEB) , ... March 28, 2017 , ... ... based in Wethersfield, Conn., has relocated its corporate headquarters to a new, more ... clients. , In October 2016, Qualidigm purchased a distressed office building in ...
(Date:3/28/2017)... , ... March 28, 2017 , ... ... plans work, the Self-Funding Success website has recently developed and published an informational ... Plans ” was created based on common inquiries the site’s team of third ...
(Date:3/28/2017)... ... March 28, 2017 , ... AutismOne announced the ... Association of Integrative Medicine and available for application on Saturday, May 27, 2017, ... Conference in Colorado Springs. , Ed Arranga, president of AutismOne, stated: "Many of ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... 27, 2017 Summary This ... Bayer and its partnering interests and activities since 2010. ... an in-depth insight into the partnering activity of one of ... company reports are prepared upon purchase to ensure inclusion of ... The report will be delivered in PDF format within ...
(Date:3/27/2017)... -- ImMAGE Biotherapeutics (OTCMKTS: IMMG), an early-stage biotechnology company, announced ... efficacy studies. The company is harnessing the power of ... A, in an effort to find a better treatment ... 4 weeks of treatment in transgenic mice, the lead ... a full toxicology report of various organs. Cytotoxic T-cells ...
(Date:3/27/2017)... 2017 To mark the end of Save Your ... leader in digital imaging solutions, will showcase Canon eye care ... New York,s Jacob Javits Center from ... sponsored by the American Optometric Association, is observed annually in ... comprehensive eye exams. In recognition of this observance, Canon ...
Breaking Medicine Technology: