Navigation Links
Suicidal Thoughts May Vary by Antidepressant
Date:10/15/2009

Men face higher risk when taking nortriptyline than escitalopram, study finds

THURSDAY, Oct. 15 (HealthDay News) -- Men who take the antidepressant nortriptyline (Aventyl) are nearly 10 times more likely to have suicidal thoughts than those who use the antidepressant escitalopram (Lexapro, Cipralex), a new study has found.

The study, published online Oct. 15 in BMC Medicine, included 811 people with moderate to severe unipolar depression. Though it found an overall reduction in suicidal thoughts, men who took nortriptyline were found to have a 9.8-fold increase in emerging suicidal thoughts and a 2.4-fold increase in worsening suicidal thoughts, compared with those who took escitalopram.

"Our findings that treatment-emerging and worsening suicidal thoughts may also be associated with psychomotor activation triggered by antidepressants need to be investigated in future studies," the study team's leader, Dr. Nader Perroud, from the Institute of Psychiatry at King's College London, said in a news release from the journal's publisher.

"The study also refutes the idea that newer antidepressants such as the SSRIs [selective serotonin reuptake inhibitors] are worse than older medications in terms of increasing suicidal thoughts," Perroud added.

Nortriptyline is a tricyclic antidepressant that inhibits the reuptake of noradrenaline and, to a lesser degree, that of serotonin, according to background information in the news release. Escitalopram is an SSRI.

More information

The U.S. Agency for Healthcare Research and Quality has more about antidepressants.



-- Robert Preidt



SOURCE: BioMed Central, news release, Oct. 15, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Victimization for sexual orientation increases suicidal behavior in college students
2. Doctors Often Fail to Spot Suicidal Patients
3. Genes Might Predispose Antidepressant Users to Suicidal Thoughts
4. Genetic test announced for suicidal ideation in patients using antidepressant drugs
5. Teens getting help for suicidal behavior from an online community
6. FDA Warning of Suicidal Risk Associated with Antidepressants in Juveniles and Young Adults Reviewed at Recent ISCTM Meeting
7. Asthma Associated With Suicidal Thoughts, Attempts
8. Poor sleep linked to suicidal behavior among children and adolescents with depressive episodes
9. Insomnia in parents can result in sleep problems, suicidal behavior among their offspring
10. Epilepsy Drugs Can Cause Suicidal Tendencies, FDA Panel Finds
11. Suicidal thoughts among college students more common than expected
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic ... Frederick area economy by obtaining investment capital for emerging technology companies. SCP ... that have already resulted in more than a million dollars of capital investment ...
(Date:6/24/2016)... ... June 24, 2016 , ... Finally, a bruise cream ... procedures, dermaka cream can be incorporated into the post-surgical treatment plans of a variety ... , dermaka cream is very effective for bruising and causes a rapid resolution ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Seema Daulat, a native Texan ... the South Lamar location as of July 13, 2016. , Dr. Daulat earned her ... medical student, she regularly volunteered at the Agape Clinic serving Dallas’ underprivileged community. , ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... FRANCISCO, Calif. , June 24, 2016 /PRNewswire/ ... ), a biopharmaceutical company developing novel therapeutics for ... unmet needs, today announced the closing of its ... of common stock, at the public offering price ... in the offering were offered by GBT. GBT ...
(Date:6/24/2016)... , June 24, 2016 The Academy ... of recommendations that would allow biopharmaceutical companies ... with entities that make formulary and coverage decisions, a ... "value" of new medicines. The recommendations address ... not appear on the drug label, a prohibition that ...
(Date:6/24/2016)... , June 24, 2016 According ... by Type (Standard Pen Needles, Safety Pen Needles), Needle ... GLP-1, Growth Hormone), Mode of Purchase (Retail, Non-Retail) - ... This report studies the market for the forecast period ... reach USD 2.81 Billion by 2021 from USD 1.65 ...
Breaking Medicine Technology: