Navigation Links
Sugar Substitutes May Contribute to Weight Gain
Date:2/11/2008

Saccharin tricked body, slowed down metabolism in rats

MONDAY, Feb. 11 (HealthDay News) -- Surprising research suggests a popular artificial sweetener has the unexpected and unwelcome effect of packing on the pounds.

Purdue researchers report that saccharin altered the ability of rats to control their appetites. However, the head of an artificial sweetener trade group scoffed at the findings, saying they don't necessarily translate to humans.

"We found that the rats that were getting artificially sweetened yogurt gained more weight and ate more food," said study author Susan Swithers, an associate professor of psychological sciences at the Ingestive Behavior Research Institute at Purdue University. "The take-home message is that consumption of artificially sweetened products may interfere with an automatic process."

That process, she said, involves the body's ability to detect that it will soon be full. "We often will stop eating before we've been able to absorb all of the calories that come from a meal. One of the reasons we might stop eating is that our experience has taught in the past that, 'After I eat this food, I'll feel this full for this long,' " she explained.

It seems to be a subconscious process based on automatic estimations of how much energy certain foods will provide, she said. For example, a sweet taste might be a sign that "calories are coming, and I should prepare my body for the arrival of those calories." However, when the sweetness is not followed by a lot of calories, the body's digestive system gets confused, and the metabolism rate does not gear up as much the next time sweetness is tasted.

To test this theory, the researchers fed two different types of plain Dannon yogurt to male rats. Some received yogurt sweetened with glucose, a form of sugar, while others ate saccharin-sweetened yogurt. All also ate unsweetened yogurt.

The rats who ate artificially sweetened yogurt consumed more food overall and gained more weight. The body temperatures of those rats also didn't rise as high as the others. "That might be a kind of measure of energy expenditure, suggesting not only are the animals eating more calories, they may be expending or burning up fewer calories," Swithers said.

The findings were published in the February issue of Behavioral Neuroscience.

Essentially, she said, it appears that the bodies of the rats are learning to not expect much in the way of calories from sweet foods. "The artificial sweetener provides the signal that not as many calories are going to come, and the animal responds by consuming more calories."

As for humans, she said, previous research has provided conflicting indications about whether obesity is a bigger problem among people who use artificial sweeteners.

According to her, launching a similar study among people would be difficult, because few have never encountered artificial sweeteners before. The next step, she said, is to do more research in rats.

Lyn Nabors, president of the Calorie Control Council trade group, lambasted the study, saying it has "no basis in science" and "no relation to the human experience whatsoever."

Artificial sweeteners can help people lose weight, she said. "The scientific community firmly believes that calories in, calories out is what makes a difference. The recommendation is that you reduce calories and exercise if you want to lose weight."

More information

Learn about cancer and artificial sweeteners from the National Cancer Institute.



SOURCES: Susan Swithers, Ph.D., associate professor, psychological sciences, Ingestive Behavior Research Center, Purdue University, West Lafayette, Ind.; Lyn Nabors, president, Calorie Control Council, Atlanta; February 2008, Behavioral Neuroscience


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Discovery of sugar sensor in intestine could benefit diabetes
2. Sugary Sodas High in Diabetes-Linked Compound
3. Cell-surface sugar defects may trigger nerve damage in multiple sclerosis patients
4. Right breakfast bread keeps blood sugar in check all day
5. Wrigleys Orbit(R), Extra(R) and Eclipse(R) Sugar-Free Chewing Gums Awarded American Dental Associations Seal of Acceptance
6. New Nutraceutical That Stabilizes Blood Sugar Naturally is Introduced
7. China Kangtai Participates in 2007 China National Sugar and Wine Products Trade Fair
8. Got sugar? Glucose affects our ability to resist temptation
9. Federal Judge Says Sugar Association Suit Accusing Johnson & Johnson of False Advertising to Go Forward
10. Carrot cake study on sugar in type 2 diabetes
11. Keep a Watchful Eye on Sugary Beverage Consumption
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sugar Substitutes May Contribute to Weight Gain
(Date:8/18/2017)... ... ... Pastor and Overseer at The House of Yahweh in Abilene, Texas, has released a new ... the mother of the Savior whom the world calls “Mother Mary”. Yisrayl says when compared ... of this historical woman. , “The world bows, kisses the feet of, cries out ...
(Date:8/18/2017)... CARMEL, IN (PRWEB) , ... August 18, 2017 , ... ... 36th annual list, the most prestigious ranking of the nation's fastest-growing private companies. This ... in the exclusive Inc. 5000 ranking . This year’s ranking reflects ASH’s 76 ...
(Date:8/18/2017)... ... 18, 2017 , ... “Our Mountains to Climb: A Journey of Love and ... stronger together through the faith they shared to overcome struggles in life. “Our Mountains ... published author, Barbara J. Corcoran, a retired teacher and happily married since 1999; the ...
(Date:8/18/2017)... ... ... “Three Narrow Roads”: a vivid and provocative look into the narrow path toward ... Sr., is currently the pastor-teacher-visionary at Simply the WORD Church, a global prayer ministry ... program geared towards youth. , King shares, “When I take time to think about ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Depressed: Super Heroes of the Bible”: ... reflect upon the stories and the relevance these tales may have on the reader’s ... Linhart, a former special education teacher, Jessica spends much of her time enjoying nature ...
Breaking Medicine News(10 mins):
(Date:7/31/2017)... July 31, 2017 7D Surgical, developer of ground ... purchased the 7D Surgical System to support its strategic sales ... D.C. and Virginia.  7D Surgical has entered into ... of the premier medical facilities within those markets. ... ...
(Date:7/28/2017)... --EnvoyHealth, a Diplomat company, has partnered with Compliance Meds ... a technology designed to improve patient medication adherence. ... solutions and services that help track and improve patients, ... LITE offers medication monitoring and control for patients and ... Records date and time of bottle ...
(Date:7/27/2017)... Pa., July 27, 2017  West Pharmaceutical Services, Inc. ... results for the second-quarter 2017 and updated financial guidance ... Second-Quarter 2017 Highlights Reported net ... over the prior-year quarter. Net sales at constant currency ... reported-diluted EPS was $0.51, compared to $0.60 in the ...
Breaking Medicine Technology: