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Sudden decline in testosterone may cause Parkinson's disease symptoms in men
Date:7/26/2013

than we thought," said Pahan. "After castration, levels of inducible nitric oxide synthase (iNOS) and nitric oxide go up in the brain dramatically. Interestingly, castration does not cause Parkinson's like symptoms in male mice deficient in iNOS gene, indicating that loss of testosterone causes symptoms via increased nitric oxide production."

"Further research must be conducted to see how we could potentially target testosterone levels in human males in order to find a viable treatment," said Pahan.


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Contact: Deb Song
deb_song@rush.edu
312-942-0588
Rush University Medical Center
Source:Eurekalert

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