Navigation Links
Successful results against human leishmaniasis with a more efficient and economic vaccine
Date:12/19/2012

A research coordinated by the UAB has succeeded in testing a vaccine against leishmaniasis. The vaccine was tested with the best animal model existing, the golden hamster, and can be produced at low costs by using insect larvae. The research, published in the latest edition of PLoS ONE, is an important step towards the fight against a disease which causes the death of 70,000 people each year in developing countries and of countless dogs, which also suffer from this disease and are its natural reservoir.

Leishmaniasis is one of the main health problems existing at global scale. It is produced by the protozoan Leishmania infantum, and canines, which can also be infected with the disease, are the main reservoirs of the organism. The disease is transmitted by insects from the Phlebotominae subfamily (sandflies), which are very similar to mosquitos. Clinical manifestations can go anywhere from minor skin sores to organ complications and, in the worst cases, death. The disease causes 70,000 deaths a year, mainly in developing countries, and affects over 12 million people around the world. Some 1.5 to 2 million new cases appear each year and an additional 350 million people are at risk of contracting the disease. Leishmaniasis is considered an endemic disease in parts of Asia, Africa, southern Europe, Mexico, Central America and South America. With the AIDS epidemic, leishmaniasis in humans has reactivated in many countries. Current treatments are unsatisfactory and, even though the most reasonable via to fight the disease would be to obtain an efficient vaccine, conventional vaccines until now have failed.

The research team led by the UAB compared the results of applying different vaccine strategies to the best animal model in which to study the human variant of the disease: the golden hamster. The results show that the most effective strategy is a combination of two vaccines created by the researchers: three doses of DNA with genes from the
'/>"/>

Contact: Maria Jesus Delgado
MariaJesus.Delgado@uab.cat
34-935-814-049
Universitat Autonoma de Barcelona
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Dr. Farshchian: Muscular Contusions are Now Being Treated Successfully at The Center for Regenerative Medicine in Miami
2. QuickMedical Announces Successful Sales and Marketing Results for 2012
3. Muscular Contusions Are Now Being Treated Successfully by Dr. Farshchian Using Cell Therapy
4. Barrow researchers successfully destroy brain tumor cells
5. Imaging facility develops successful radiation dose reduction program
6. Study IDs 4 Key Habits of Successful Aging
7. Study: Clot removal devices successful tools for acute ischemic stroke treatment
8. New drug successfully halts fibrosis in animal model of liver disease
9. Health coaches could be key to successful weight loss, study suggests
10. DermaShoppe.com Celebrates Its Second Successful Year in Online Skin Care
11. Online weight loss programs that feature successful dieters may help
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... 17, 2014) Doctors who treat patients with ... (LAM) can face an agonizing treatment decision. , ... disease and help relieve shortness of breath. But ... sirolimus can cause potentially fatal complications following transplantation. ... Daniel Dilling, medical director of Loyola University Medical ...
(Date:4/17/2014)... affects about one in five infants in the United ... the first several months after birth. Research into probiotic ... however, the April 1, 2014 issue of the ... a study, "Probiotics and Infant Colic," concluding that the ... infant colic did not reduce crying or fussing ...
(Date:4/17/2014)... April 17, 2014 EcoHealth Alliance, a nonprofit ... issues, published a comprehensive review today examining the current ... virus. The review calls for improved global surveillance strategies ... the recent outbreak of Ebola in West Africa that ... countries of Guinea and Liberia. According to the ...
(Date:4/17/2014)... An international research team led by Cesar A. Arias, ... Center at Houston (UTHealth) has identified a new superbug ... The report appeared in the April 17 issue of ... The new superbug is part of a class of ... or MRSA, which is a major cause of hospital ...
(Date:4/17/2014)... Meaningful long-term survival is possible for selected patients ... treated with cytoreductive surgery with Hyperthermic IntraPeritoneal Chemotherapy, ... physicians at Wake Forest Baptist Medical Center. , ... experience with cytoreductive surgery and HIPEC, said lead ... 20 years, worth of patient data shows that ...
Breaking Medicine News(10 mins):Health News:Patients with rare lung disease face agonizing treatment dilemma 2Health News:Patients with rare lung disease face agonizing treatment dilemma 3Health News:New study says probiotic use for infant colic is not effective in reducing symptoms 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 3Health News:New MRSA superbug emerges in Brazil 2Health News:20 years of data shows treatment technique improvement for advanced abdominal cancer 2
... , SATURDAY, July 30 (HealthDay News) -- A new study ... users obsessively check their devices for e-mails, social media and ... the United States and Finland, and found that they checked ... less than 30 seconds and involves opening the screen lock ...
... , Alexandria, VA Tobacco related disease is a ... studies suggest that "alternative" tobacco products may have supplanted ... African Americans, according to new research published in the ... Neck Surgery. While the tobacco-related disease ...
... In an effort to reduce the radiation dose delivered by ... a comprehensive CT radiation dose reduction program which has allowed ... at their facility, according to an article in the August ... Radiology . CT is an essential tool ...
... approaches to dietary counseling for obesity are heavily rooted ... the ability to choose healthy foods and portion ... comfort foods. According to preventive medicine ... supports a new counseling approach that views obesity as ...
... FRIDAY, July 29 (HealthDay News) -- Any time there,s a ... at a youth camp in Norway, the shootings of a ... -- one question seems to ring clearer than others: Why ... disturbed and capable of committing deadly violence? Psychiatrists and ...
... , SATURDAY, July 30 (HealthDay News) -- Daughters have ... mothers, but there is no similar effect the other ... that teens may have more impact on their parents ... The study included 343 mother-daughter pairs who completed ...
Cached Medicine News:Health News:Smartphones Really Are Habit-Forming: Study 2Health News:Effects of tobacco use among rural African American young adult males 2Health News:Community hospital implements successful CT radiation dose reduction program 2Health News:Obesity counseling should focus on neurobehavioral processes, not personal choice, researchers say 2Health News:Obesity counseling should focus on neurobehavioral processes, not personal choice, researchers say 3Health News:Shootings Spark Interest in Spotting the Violence-Prone 2Health News:Shootings Spark Interest in Spotting the Violence-Prone 3
(Date:1/14/2014)... Minn. , Jan. 14, 2014   NuAire , a manufacturer ... to agreement with Hitachi Koki of Japan ... in North America . NuAire will utilize its ... and Canada to offer assistance in ...
(Date:1/14/2014)... Inc. , a privately held company pioneering the development ... related neurodegenerative disorders, announced today the relocation of its ... as of January 15, 2014 and expanded lease agreement ... Oligomerix, which is focused on the development ...
(Date:1/14/2014)... 14, 2014   Evidera , a leading provider of ... Center for Drug Evaluation and Research (CDER), U.S. Food ... guidance document for a patient-reported outcome (PRO) measure in ... Disease Tool [EXACT] for Measurement of Symptoms of Acute ...
Breaking Medicine Technology:NuAire announces sales and service of Hitachi Koki centrifuges in North America 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 2Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 3Evidera Announces Release of FDA Draft Guidance on Use of the "EXACT" to Measure Symptoms of COPD Exacerbations 4
... and BEDMINSTER, N.J., Aug. 31 QRxPharma (ASX: QRX ... symposium at the 13th World Congress of Pain on ...  The symposium, titled "Dual Opioid Therapy: Changing the Paradigm" ... an immediate-release Dual Opioid product for moderate to severe ...
... plc (LSE: SHP, NASDAQ: SHPGY ), ... for inflammatory bowel disease (IBD) fellowships at leading medical ... in 2011 and will provide a year of training ... completed a fellowship in gastroenterology. "We are ...
Cached Medicine Technology:QRxPharma to Sponsor Symposium at 13th World Congress on Pain Meeting 2QRxPharma to Sponsor Symposium at 13th World Congress on Pain Meeting 3Shire Announces Support for Inflammatory Bowel Disease (IBD) Fellowships at Leading Medical Institutions Nationwide 2Shire Announces Support for Inflammatory Bowel Disease (IBD) Fellowships at Leading Medical Institutions Nationwide 3
ApolipoproteinA-1 & B Calibrator...
CRP Calibrator...
Fructosamine controls level 3...
Drug controls sera available in three levels for the control of accuracy and percision for up to 18 analytes...
Medicine Products: