Navigation Links
Successful results against human leishmaniasis with a more efficient and economic vaccine
Date:12/19/2012

A research coordinated by the UAB has succeeded in testing a vaccine against leishmaniasis. The vaccine was tested with the best animal model existing, the golden hamster, and can be produced at low costs by using insect larvae. The research, published in the latest edition of PLoS ONE, is an important step towards the fight against a disease which causes the death of 70,000 people each year in developing countries and of countless dogs, which also suffer from this disease and are its natural reservoir.

Leishmaniasis is one of the main health problems existing at global scale. It is produced by the protozoan Leishmania infantum, and canines, which can also be infected with the disease, are the main reservoirs of the organism. The disease is transmitted by insects from the Phlebotominae subfamily (sandflies), which are very similar to mosquitos. Clinical manifestations can go anywhere from minor skin sores to organ complications and, in the worst cases, death. The disease causes 70,000 deaths a year, mainly in developing countries, and affects over 12 million people around the world. Some 1.5 to 2 million new cases appear each year and an additional 350 million people are at risk of contracting the disease. Leishmaniasis is considered an endemic disease in parts of Asia, Africa, southern Europe, Mexico, Central America and South America. With the AIDS epidemic, leishmaniasis in humans has reactivated in many countries. Current treatments are unsatisfactory and, even though the most reasonable via to fight the disease would be to obtain an efficient vaccine, conventional vaccines until now have failed.

The research team led by the UAB compared the results of applying different vaccine strategies to the best animal model in which to study the human variant of the disease: the golden hamster. The results show that the most effective strategy is a combination of two vaccines created by the researchers: three doses of DNA with genes from the
'/>"/>

Contact: Maria Jesus Delgado
MariaJesus.Delgado@uab.cat
34-935-814-049
Universitat Autonoma de Barcelona
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Dr. Farshchian: Muscular Contusions are Now Being Treated Successfully at The Center for Regenerative Medicine in Miami
2. QuickMedical Announces Successful Sales and Marketing Results for 2012
3. Muscular Contusions Are Now Being Treated Successfully by Dr. Farshchian Using Cell Therapy
4. Barrow researchers successfully destroy brain tumor cells
5. Imaging facility develops successful radiation dose reduction program
6. Study IDs 4 Key Habits of Successful Aging
7. Study: Clot removal devices successful tools for acute ischemic stroke treatment
8. New drug successfully halts fibrosis in animal model of liver disease
9. Health coaches could be key to successful weight loss, study suggests
10. DermaShoppe.com Celebrates Its Second Successful Year in Online Skin Care
11. Online weight loss programs that feature successful dieters may help
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... (PRWEB) September 17, 2014 In Pretrial ... that “bi-weekly telephonic discovery conferences would be beneficial in ... conferences through mid-December. “At the end of December,” the ... the need for additional conferences. , “The plain ... that there is still much to be discussed as ...
(Date:9/17/2014)... 2014 (HealthDay News) -- Positive messages about the health ... the habit, a new study suggests. Although smokers ... "loss-framed" messages about the harmful effects of smoking, researchers ... want benefit more from "gain-framed," or positive, messages about ... concluded that using a mix of both types of ...
(Date:9/17/2014)... Many countries choose to kill all infected poultry ... number of poultry exceeds 10 billion in China. Epidemic ... huge losses. Therefore, it is quite necessary to immunize ... vaccines have been used for more than 10 years ... use H5N1 avian influenza vaccines voluntarily 10 years ago ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 StartX ... revealed 12 companies raising rounds of funding at its ... few hundred investors and media, was the first such ... located next to the university. The presentations were delivered ... adjacent to StartX-QB3 Labs, a 2,000 square foot life ...
(Date:9/17/2014)... The Delta Dental Community Care Foundation announced today ... Health Foundation: America’s ToothFairy (NCOHF) to support oral health ... Zone Program® in California. , The Orange County NCOHF ... local constituent groups and stakeholders in a comprehensive approach ... its devastating effects on local families. The support of ...
Breaking Medicine News(10 mins):Health News:Transvaginal Mesh Lawsuit News: New Order in C.R. Bard MDL Sets Schedule of Conferences for September to December, the Rottenstein Law Group LLP Reports 2Health News:More Than One Kind of Message May Convince Smokers to Quit, Study Says 2Health News:China Avian Influenza Vaccine Industry 2014-2018 Research Report Now Available at LifeScienceIndustryResearch.com 2Health News:China Avian Influenza Vaccine Industry 2014-2018 Research Report Now Available at LifeScienceIndustryResearch.com 3Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 2Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 3Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 4Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 5Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 6Health News:Delta Dental Community Care Foundation Donation to America's ToothFairy Helps Deliver Critical Services 2
... multi-center U.S. registry on the efficacy of carotid stenting ... are at high risk for standard surgical therapy.// ... CAPTURE (Carotid ACCULINK/ACCUNET Post Approval Trial to Uncover Rare ... Cardiology’s 55th Annual Session in Atlanta. The multi-center study ...
... with a friend will be more beneficial to health than ... Elizabeth Gould at Harvard University compared the costs and benefits ... and found that contrary to accepted wisdom, jogging was not ... Daily Mail. ,The researchers carried out series of ...
... Hopkins University School of Medicine said that genetic material in ... // , The researchers feel that it very ... of mutated human genes. ,Jef Boeke described about ... the yeast cells which is necessary for the stability of ...
... spells doom for global economic growth. According to bank economist ... a dent of two to six percentage out of global ... rate reductions and older populations, which will lead to continued ... Burns, has been getting Bay Street and investors to gear ...
... at the end of the tunnel. Those infected with human ... workplaces. // Employers will have to face legal charges if ... ,HIV causes acquired immune deficiency syndrome. The ministry of ... of HIV/AIDS, which will seek to protect the rights of ...
... and 170 suspected cases of meningococcimia or meningitis in New ... who are taking strict measures to check the spread of ... sure that family members and neighbors of infected persons are ... also distributing leaflets to educate people about the symptoms of ...
Cached Medicine News:Health News:Carotid Stenting Can Help Patients With Silent Disease 2Health News:Carotid Stenting Can Help Patients With Silent Disease 3Health News:Carotid Stenting Can Help Patients With Silent Disease 4
(Date:9/17/2014)... DALLAS , September 17, 2014 ... Electronics Market by Component (Sensor, Battery, Memory Device, Display, ... and Fitness & Wellness), and by Geography - Global ... of medical electronics market is expected to reach $56.50 ... from 2014 to 2020. Browse 235 market ...
(Date:9/17/2014)... 2014  NuView Life Sciences, Inc. (NuView) announced ... agreement with Otsuka Pharmaceutical Co., Ltd. (Otsuka) to ... biomarker to detect cancers of the breast and ... diagnostic-imaging applications. NuView retains all rights for the ... urine screen applications. Under the terms ...
(Date:9/17/2014)... Isis Pharmaceuticals, Inc. (NASDAQ: ... $4 million milestone payment from Achaogen, Inc. (NASDAQ: ... of a Phase 3 study of plazomicin in ... infections.  The Phase 3 study is designed as ... safety of plazomicin compared to colistin in patients ...
Breaking Medicine Technology:Medical Electronics Market Worth $56.50 Billion by 2020 2Medical Electronics Market Worth $56.50 Billion by 2020 3Medical Electronics Market Worth $56.50 Billion by 2020 4NuView Life Sciences Enters Global Licensing Agreement With Otsuka Pharmaceutical 2NuView Life Sciences Enters Global Licensing Agreement With Otsuka Pharmaceutical 3NuView Life Sciences Enters Global Licensing Agreement With Otsuka Pharmaceutical 4NuView Life Sciences Enters Global Licensing Agreement With Otsuka Pharmaceutical 5Isis Pharmaceuticals Earns $4 Million from Achaogen for the Initiation of a Phase 3 Study of Plazomicin 2Isis Pharmaceuticals Earns $4 Million from Achaogen for the Initiation of a Phase 3 Study of Plazomicin 3
... Belt Technologies, Inc., a Pittsburgh based medical device company ... use in orthopaedic and neurosurgery procedures, has closed on ... financing. The round was led by private investors ... Works (Pittsburgh) and consisted of both new investments and ...
... Sept. 30 Law firm Clifford Chance, as international counsel, ... with Wyeth under China,s Anti-Monopoly Law. The clearance was issued ... , Competition approval from the Chinese authorities was one of ... The EU has already approved the deal; decisions are awaited ...
Cached Medicine Technology:Blue Belt Technologies, Inc. Closes Series A Financing 2Blue Belt Technologies, Inc. Closes Series A Financing 3Clifford Chance Advises Pfizer on Conditional Clearance in China of Its Merger with Wyeth 2
... anesthesia workstation provides an intelligent approach ... to provide true clinical benefits to ... the art computer technology integrates hemodynamic ... color touchscreen display panel. The open ...
... Cost effective technology in anesthesia., ,Whether ... manual ventilation, the operating theater or as ... integrated monitoring, the Aliseo product family allows ... ,With three product models, you have ...
... in facilities where space is a premium ... gas delivery technologies with an ergonomic and ... functionality of the Draeger Infinity patient monitoring ... workplace environment that is a sound investment ...
... A new level of excellence and ... advanced anesthesia delivery system with basic ventilation ... industry leading excellence of the Aestiva/5 Anesthesia ... compact design - it features a configurable ...
Medicine Products: