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Successful neurosurgery with transcranial MR-guided high-intensity focused ultrasound
Date:6/22/2009

treated at the Children's Hospital Zurich with this new neurosurgical procedure in the context of a clinical study. All interventions were completed successfully and without complications. This novel technology now opens up new horizons allowing to develop non-invasive intervention procedures for a variety of brain diseases including brain tumors.

The whole surgical procedure is planned and monitored in real time by magnetic resonance imaging (MRI). The HIFU beams produced by 1024 transducers are transferred through the intact skull of the patient into the brain and concentrated onto a focus of 3 to 4 millimeters in diameter. Thus, sharply defined targets deep inside the brain are coagulated by heating them up to a focal temperature of 60 degrees Celsius. The temperature increase during the sequential sonications", each lasting 10 to 20 seconds, is continuously displayed and controlled on precise MR-temperature distribution maps. The whole surgical procedure lasts several hours and is performed without anaesthesia. Patients are awake and fully conscious during the intervention.

A project of the National Centre of Competence in Research (NCCR) Co-Me

In the context of the Swiss National Research Program NCCR Co-Me (computer aided and image guided medical interventions), the potential of non-invasive, transcranial MR-guided high-intensity focused ultrasound (tcMRgHIFU) is investigated in clinical studies at the University Children's Hospital Zurich. Scientists working in the Co-Me program pursue the goal of establishing and developing surgical interventions by means of tcMRgHIFU, in order to broaden the spectrum of completely non-invasive interventions for functional neurosurgery and for the treatment of brain tumors, stroke and various neurological brain disorders by targeted drug delivery.

The research project represents a co-operation between the University of Zurich and the ETH Zurich, through (A) the Magnetic Resonance
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Contact: Beat Werner
beat.werner@kispi.uzh.ch
41-442-668-123
University of Zurich
Source:Eurekalert  

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