Navigation Links
Substantial recovery rate with placebo effect in headache treatment
Date:5/22/2011

Lombard, IL, May 23, 2011 Headache is a very common complaint, with over 90% of all persons experiencing a headache at some time in their lives. Headaches commonly are tension-type (TTH) or migraine. They have high socioeconomic impact and can disturb most daily activities. Treatments range from pharmacologic to behavioral interventions. In a study published online today in the Journal of Manipulative and Physiological Therapeutics, a group of Dutch researchers analyzed 119 randomized controlled clinical trials (RCTs) and determined the magnitude of placebo effect and no treatment effect on headache recovery rate.

"Although the intention of control and placebo interventions in research studies is to be relatively ineffective, the question rises as to what factors might cause improvement seen in these groups," commented corresponding investigator Arianne P. Verhagen, PhD, Assistant Professor, Department of General Practice, Erasmus Medical Center, Rotterdam, The Netherlands. "The aim of this study was to analyze the observed effects in the 'no treatment' and placebo control groups in clinical trials with TTH and migraine patients."

In the headache clinical trials studied, the "no treatment" and placebo groups had a high overall recovery rate of 36%. Control groups in pharmacological trials showed a higher response rate than the behavioral (non-pharmacological) trials (38.5% vs. 15.0%). Patients had higher recovery rates in the acute treatments compared with the prophylactic treatments (39.6% vs. 32.8%). Knowing that a substantial portion of patients improve without treatment is important when considering the benefits and risks of daily headache treatment.

Pharmacological treatment typically starts when non-pharmacological treatments like lifestyle changes, relaxation therapy, cognitive therapy, and reassurance do not work. Many of the prescribed or over-the-counter medications, such as non-steroidal anti-inflammatory drugs (NSAIDs), may lead to adverse events and medication overuse headache. Considering the risks of adverse events, the authors recommend that "the prescription of medication needs to be carefully considered and evaluated with each individual patient. Because of the recovery results in 'no treatment' control groups in pharmacological trials, the question rises whether or not this way of prescription is always preferable over no treatment (wait and see) especially in the TTH population."


'/>"/>

Contact: Claire Johnson
jmptmedia@elsevier.com
630-297-3290
Elsevier Health Sciences
Source:Eurekalert

Related medicine news :

1. Emergency department CT exams of children have increased substantially
2. Influence of skin cancer on quality of life appears more substantial for women
3. Emergency departments see substantial increase in CT exams
4. Substantial consumption of fluoride increases chance of mild fluorosis
5. Legalizing marijuana in California would not substantially cut cartel revenues, study finds
6. Research Reveals Cancer Drug Effectiveness Substantially Advanced
7. MDS Announces Substantial Issuer Bid
8. Rep. Giffords to Get Skull Patch in Latest Step in Recovery
9. Hormone improves long-term recovery from stroke
10. Bringing Partner Into Anorexia Treatment May Aid Recovery
11. U. Iowa study suggests antidepressants aid physical recovery in stroke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... ... March 30, 2017 , ... ... eve of Autism Awareness Month, representatives from Organic Consumers Association, National Health Freedom ... For Health Foundation, A Voice for Choice, Moms Across America, Freedom and Ethics ...
(Date:3/30/2017)... ... March 30, 2017 , ... ... letter to President Trump expressing their support for an independent Vaccine Safety Commission. ... scientists and one medical journalist, will hold a press conference at 9:00 ...
(Date:3/29/2017)... NY (PRWEB) , ... March 29, 2017 , ... ... men’s and women’s professional squash, announced it has enlisted New York City-based sports ... The agency will develop and procure sponsorship opportunities for the Professional Squash Association ...
(Date:3/29/2017)... , ... March 30, 2017 , ... Youth Futures International ... success and feedback from high school and college students who have participated in the ... July 7-23 and YFI is now accepting applications for enrollment. Visit http://www.ghana.yfiexperience.org ...
(Date:3/29/2017)... Baton Rouge, Louisiana (PRWEB) , ... March 29, ... ... trademarked HeartBoost in three Hours at a Walgreens store in Mississippi. AngioGenesis Labs, ... campaign at Walgreens Stores in two southeastern states. Ingredients in HeartBoost, an over ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... Mar. 29, 2017 Research and Markets has announced ... Patients Treated at Proton Therapy Centers & Forecast" report to their ... The South Korean ... current market size in 2016. The Untapped Proton Therapy Market for ... USD in 2016. Proton Therapy plays an important role ...
(Date:3/29/2017)... 29, 2017  The leader in accelerated orthodontics, OrthoAccel ... Sam Daher , Manal Ibrahim , Kenji ... will be the featured microlecture presenters at the AcceleDent ... of Orthodontists (AAO) Annual Session, April 21-25, 2017. Orthodontists ... beginning daily at 11:20 a.m. On the opening morning ...
(Date:3/29/2017)... 2017  Maxor National Pharmacy Services, LLC ("Maxor"), a ... named Leah Bailey as General Counsel.  Bailey will ... company. With more than 13 years of ... focused on health care, Bailey joins the Maxor team ... Bailey advised the PBM, Specialty, and Mail Order business ...
Breaking Medicine Technology: